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pro vyhledávání: '"K W, Peden"'
Autor:
K W, Peden, J M, Farber
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 48
Publikováno v:
Virus genes. 16(2)
The simian virus 40 (SV40) large T antigen is a 708 amino-acid protein possessing multiple biochemical activities that play distinct roles in productive infection or virus-induced cell transformation. The carboxy-terminal portion of T antigen include
Publikováno v:
AIDS research and human retroviruses. 12(3)
Autor:
K W, Peden
Publikováno v:
Journal of acquired immune deficiency syndromes. 5(3)
Plasmid proviral molecular clones of the LAI isolate of HIV-1 and the ROD isolate of HIV-2 were originally prepared in moderate copy number plasmids derived from pBR322, which contains the colE1 origin of replication. In these plasmid vectors, the HI
Publikováno v:
Molecular and Cellular Biology. 6:1117-1128
To define the sequence elements involved in initiation of DNA synthesis at the simian virus 40 origin of replication, we determined the relative replication efficiencies in vitro and in vivo of templates containing a variety of mutations within the o
Publikováno v:
Journal of Virology. 61:436-445
We constructed a collection of linker insertion mutants in the simian virus 40 (SV40) genome and studied several of these with changes limited to a part of the large T antigen gene corresponding to an amino acid sequence shared with other ATPases. Tw
Autor:
Kenneth J. Soprano, Renato Baserga, Norbel Galanti, Gerald J. Jonak, J M Pipas, S McKercher, K W Peden
Publikováno v:
Molecular and Cellular Biology. 3:214-219
The biological activity of several deletion mutants of simian virus 40, cloned in pBR322, was determined. Three functions of the simian virus 40 A gene were studied: (i) the ability to express T antigen; (ii) the ability to induce cell DNA replicatio