Zobrazeno 1 - 10
of 29
pro vyhledávání: '"K W, Moore"'
Publikováno v:
The Journal of Immunology. 152:1821-1829
cDNA clones encoding a human IL-10R (hIL-10R) from a Burkitt lymphoma cell line, BJAB, express a 90 to 110 kDa polypeptide in COS7 cells that binds hIL-10 specifically. The predicted amino acid sequence of hIL-10R is 60% identical and 73% similar to
Publikováno v:
Proceedings of the National Academy of Sciences. 90:11267-11271
We isolated cDNAs encoding a mouse interleukin 10 receptor (mIL-10R) from mouse mast cell and macrophage cell lines. The two cDNAs are substantially identical and express an approximately 110-kDa polypeptide in COS7 cells, which binds mIL-10 specific
Publikováno v:
The Journal of Immunology. 148:3618-3623
The nucleotide sequence of a 7.2-kb segment containing the mouse IL-10 (mIL-10) gene was determined. Comparison to the mIL-10 cDNA sequence (Moore, K. W., et al. 1990. Science 248:1230; 250:494) revealed the presence of five exons that span approxima
Autor:
A, Zlotnik, K W, Moore
Publikováno v:
Cytokine. 3:366-371
Publikováno v:
The Journal of Immunology. 145:4167-4173
We identified a new cytokine, B cell-derived T cell growth factor (B-TCGF), that is produced by a murine B cell lymphoma and induces proliferation of mature and immature thymocytes in the presence of IL-2 and IL-4. Both adult and day 15 fetal thymocy
Publikováno v:
The Journal of Immunology. 144:1974-1982
We have isolated cDNA clones encoding a mouse low affinity receptor for IgE (Fc epsilon RII) from a cDNA library of BALB/c splenic B cells activated with LPS and IL-4. The 2.2-kb cDNA clone encodes a 331 amino acid membrane glycoprotein that is homol
Autor:
K W, Moore, R L, Stepien
Publikováno v:
Journal of veterinary internal medicine. 15(4)
Four adult dogs with polycythemia secondary to reversed patent ductus arteriosus (rPDA) were treated with hydroxyurea, a myelosuppressive agent, for 6-22 months. Regardless of initial hematocrit, clinical signs attributed to the presence of polycythe
Publikováno v:
Journal of molecular biology. 268(2)
The crystal structure of Epstein-Barr virus protein BCRF1, an analog of cellular interleukin-10 (IL-10), has been determined at the resolution of 1.9 A and refined to an R-factor 0.191. The structure of this cytokine is similar to that of human IL-10
Autor:
Y, Liu, R, de Waal Malefyt, F, Briere, C, Parham, J M, Bridon, J, Banchereau, K W, Moore, J, Xu
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(2)
BCRF1 is an EBV homologue of human IL-10 (hIL-10) and is known as viral IL-10 (vIL-10). As found earlier for the effects of vIL-10 on mouse mast cells and CD4+ T cells, the efficiency of inhibition by vIL-10 of IL-2 production by human CD4+ T cell cl
Autor:
A S, Ho, K W, Moore
Publikováno v:
Therapeutic immunology. 1(3)
The cytokine interleukin-10 (IL-10) has several important activities on cells of the immune system. IL-10 profoundly suppresses activation of macrophages, inhibiting their ability to secrete cytokines and serve as accessory cells for stimulation of T