Zobrazeno 1 - 10
of 14
pro vyhledávání: '"K V Lisovskaya"'
Autor:
V. Yu. Kost, O. A. Sukhova, I. I. Akopova, E. O. Gorbacheva, K. V. Lisovskaya, A. A. Rtishchev, S. G. Markushin
Publikováno v:
Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 0, Iss 6, Pp 21-29 (2019)
Aim. Study of changes in the phenotypic characteristics of the virulent A/WSN/33 (H1N1) strain of influenza A virus under the influence of the inclusion of site-specific mutations in the PB1-gene of this strain.Materials and methods. Using a two-step
Externí odkaz:
https://doaj.org/article/7762455f28054d108140b6358d496b16
Publikováno v:
Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 0, Iss 2, Pp 68-76 (2019)
Aim. Study of biological properties of attenuated variants of the virulent A/WSN/33 strain of influenza virus, obtained by the site-specific mutagenesis of PB2-gene. Materials and methods. Site-specific mutants of A/WSN/33 of influenza virus, having
Externí odkaz:
https://doaj.org/article/76ab6fd5ad0c4a2ba9e1de153c1f52e7
Autor:
A. A. Rtischev, R. R. Mintaev, V. Yu. Kost, I. B. Koptyaeva, I. I. Akopova, K. V. Lisovskaya, S. G. Markushin
Publikováno v:
Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 0, Iss 2, Pp 45-53 (2017)
Aim. Study the possibility of obtaining attenuated variants of influenza virus by including specially selected site-specific mutations into a conservative sequence of PA-gene (terminal segment of COOH-domain of the PA-gene) of a virulent strain. Mate
Externí odkaz:
https://doaj.org/article/baff44e378524d9ab29e8b874d9e4f1d
Publikováno v:
Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 0, Iss 2, Pp 49-56 (2016)
Aim. Study of mechanisms of attenuation of cold-adapted (ca) influenza virus strain A/ Krasnodar/101/35/59 (H2N2), associated with disruption of NS1 protein functions. Materials and methods. Study of interferonogenic activity of ca strain A/Krasnodar
Externí odkaz:
https://doaj.org/article/485fca7ec6fc4b978483a89942aefbbb
Publikováno v:
Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 92, Iss 5, Pp 27-32 (2015)
Aim. Study of ts, ca, att phenotype, immunogenicity and protective effectiveness of reas-sortants, obtained by a way of recombination of a new influenza cold-adapted (ca) strain donor of attenuation A/Krasnodar/101/35/59 (H2N2) and virulent strain of
Externí odkaz:
https://doaj.org/article/bb04b7e363fe47c686a1dbc23b735d5f
Autor:
R R Mintaev, L B Koptyaeva, V Yu Kost, A A Rtischev, I I Akopova, K V Lisovskaya, S.G. Markushin
Publikováno v:
Журнал микробиологии, эпидемиологии и иммунобиологии, Vol 0, Iss 2, Pp 45-53 (2017)
Aim. Study the possibility of obtaining attenuated variants of influenza virus by including specially selected site-specific mutations into a conservative sequence of PA-gene (terminal segment of COOH-domain of the PA-gene) of a virulent strain. Mate
Autor:
A A, Rtischev, R R, Mintaev, V Yu, Kost, L B, Koptyaeva, I I, Akopova, K V, Lisovskaya, S G, Markushin
Publikováno v:
Zhurnal mikrobiologii, epidemiologii i immunobiologii. (2)
Study the possibility of obtaining attenuated variants of influenza virus by including specially selected site-specific mutations into a conservative sequence of PA-gene (terminal segment of COOH-domain of the PA-gene) of a virulent strain.A/ WSN/33
Publikováno v:
Zhurnal mikrobiologii, epidemiologii i immunobiologii. (2)
Study of mechanisms of attenuation of cold-adapted (ca) influenza virus strain A/ Krasnodar/101/35/59 (H2N2), associated with disruption of NS1 protein functions.Study of interferonogenic activity of ca strain A/Krasnodar/101/35/59 (H2N2), its parent
Autor:
T E, Medvedeva, K V, Lisovskaya, F I, Polezhaev, L M, Garmashova, G I, Alexandrova, Y Z, Ghendon
Publikováno v:
Acta virologica. 28(3)
The ts phenotype and location of ts mutations were studied in the genome of parent viruses and those obtained by recombination of cold-adapted strains A/Leningrad/134/17/57 or A/Leningrad/134/47/57 with epidemic H1N1 and H3N2 influenza A virus strain
Autor:
T E Medvedeva, Alexander Klimov, K V Lisovskaya, F.I. Polezhaev, Y Z Ghendon, G I Alexandrova
Publikováno v:
Infection and immunity. 44(3)
A previously described cold-adapted attenuated virus, A/Leningrad/134/17/57 (H2N2), was further modified by 30 additional passages in chicken embryos at 25 degrees C. This virus had a distinct temperature-sensitive (ts) phenotype, grew well in chicke