Zobrazeno 1 - 10
of 78
pro vyhledávání: '"K V Chin"'
Autor:
M. A. Beaven, Y. S. Cho-Chung, Jacques Emile Dumont, T. T. Puck, L. S. Weistein, Jérôme Bertherat, S. M. Jan de Beur, Charis Eng, G. Tortora, W. R. Miller, K. V. Chin, Constantine A. Stratakis, E. Severin, G. M. Kammer, P. S. Amieux
Publikováno v:
Hormone and Metabolic Research. 34:169-175
This report summarizes several aspects of protein kinase A (PKA) signaling and its involvement in health and disease. It follows the discovery that PRKAR1A, the gene that codes for the relatively abundant regulatory subunit type 1A of protein kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a85a0bbc7032c973651be0440d8b2c3d
https://doi.org/10.1055/s-2002-26710
https://doi.org/10.1055/s-2002-26710
Akademický článek
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Autor:
K, Kudoh, M, Ramanna, R, Ravatn, A G, Elkahloun, M L, Bittner, P S, Meltzer, J M, Trent, W S, Dalton, K V, Chin
Publikováno v:
Cancer research. 60(15)
Drug resistance in cancer is a major obstacle to successful chemotherapy. Cancer cells exposed to antitumor drugs may be directly induced to express a subset of genes that could confer resistance, thus allowing some cells to escape killing and form t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aca26950fdb3677307305696bad5f069
https://pubmed.ncbi.nlm.nih.gov/10945624
https://pubmed.ncbi.nlm.nih.gov/10945624
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(6)
The role of cAMP in cell growth and differentiation, gene expression, and neuronal function is mediated by the cAMP-dependent protein kinase (PKA). Differential expression of type I and type II PKA has been correlated with neoplastic transformation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27bf062c5102d2aef2b9b5a15309a384
https://pubmed.ncbi.nlm.nih.gov/10873081
https://pubmed.ncbi.nlm.nih.gov/10873081
Publikováno v:
Anticancer research. 18(5A)
The emergence of cisplatin resistance poses a significant problem to the treatment of a variety of human malignancies. Therefore, understanding the molecular basis of cisplatin resistance could improve the clinical effectiveness of this anticancer ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ace3a324ce4ce674170a5aa661d8c50
https://pubmed.ncbi.nlm.nih.gov/9858882
https://pubmed.ncbi.nlm.nih.gov/9858882
Autor:
M E, Cvijic, K V, Chin
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 8(12)
Multidrug resistance (MDR) in cancer poses a major obstacle to the success of chemotherapy. We previously reported that cyclic AMP (cAMP)-resistant mutants of the Chinese hamster ovary and the mouse adrenal cortical carcinoma cells harboring defectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42b028274d10d8970048a25e201339a2
https://pubmed.ncbi.nlm.nih.gov/9419412
https://pubmed.ncbi.nlm.nih.gov/9419412
Autor:
M E, Cvijic, K V, Chin
Publikováno v:
International journal of cancer. 72(2)
The signal transduction pathway of cAMP, mediated by the cAMP-dependent protein kinase (PKA), is involved in the regulation of metabolisms, cell growth and differentiation and gene expression. Isolated PKA mutants from Chinese hamster ovary (CHO) cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f3ff7c4d16e3a1a7d9d5016d5991d066
https://pubmed.ncbi.nlm.nih.gov/9219844
https://pubmed.ncbi.nlm.nih.gov/9219844
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 7(8)
Drug resistance in cancer poses a major problem to the success of chemotherapy. Increased resistance to the DNA-damaging chemotherapeutic drug cisplatin may be associated with a variety of factors including decreased drug accumulation, increased intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31fc626be09c5835037f4dd2e6f11f11
https://pubmed.ncbi.nlm.nih.gov/8853907
https://pubmed.ncbi.nlm.nih.gov/8853907
Publikováno v:
Cancer research. 56(15)
Indirect evidence has suggested that P-glycoprotein (P-gp), the multidrug transporter, is phosphorylated by protein kinase C (PKC) and that phosphorylation modulates its transport function. To address the first premise more directly, ie., that P-gp i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39ef97253a7e226eac01b3cd94f4da38
https://pubmed.ncbi.nlm.nih.gov/8758935
https://pubmed.ncbi.nlm.nih.gov/8758935
Publikováno v:
Oncogene. 12(3)
We have explored the relationship between DNA repair and transcription in vivo. A gene-specific repair assay has been employed to study removal of ultraviolet light-induced cyclobutane pyrimidine dimers in the MDR1 gene at different levels of MDR1 mR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::924ceb36afb76b71c7efe0f7bf8aad48
https://pubmed.ncbi.nlm.nih.gov/8637722
https://pubmed.ncbi.nlm.nih.gov/8637722