Výsledky vyhledávání

The Effects of Synthetic Conjugated Estrogens, A (Cenestin) on Trabecular Bone Structure and Strength in the Ovariectomized Rat Model

Autor: M. Khan, S. Majumdar, Jeffrey C. Lotz, Nancy E Lane, R. E. Stevens, J. L. Kumer, R. Klein, K. V. Phelps

Publikováno v: Osteoporosis International. 13:816-823

This study evaluated the effect of Cenestin, a synthetic conjugated estrogens product, on the maintenance of trabecular bone microarchitecture, bone strength, and of bone turnover in the ovariectomized (ovx) rat model. Two doses of Cenestin were chos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b8857f345ead21cb27311f4f23776e
https://doi.org/10.1007/s001980200113

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Evaluation of Single- and Multiple-Dose Pharmacokinetics of Synthetic Conjugated Estrogens, A (Cenestin®) Tablets: A Slow-Release Estrogen Replacement Product

Autor: Ruth E. Stevens, K. V. Phelps, P. Roy

Publikováno v: The Journal of Clinical Pharmacology. 42:332-341

A multiple-dose, placebo-controlled, randomized pharmacokinetic study was performed in 15 early (i.e., 1-3 years) postmenopausal women to evaluate the single and steady-state pharmacokinetics of 0.625 mg Cenestin (Synthetic Conjugated Estrogens, A) t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63ff7074aaaf4d3ecefb82e65fd9df3
https://doi.org/10.1177/00912700222011256

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Perimenopausal women in estrogen vasomotor trials: contribution to placebo effect and efficacy outcome

Autor: K. V. Phelps, James A. Simon, R. E. Stevens, Stacey A. Ayres

Publikováno v: Climacteric. 4:19-27

Objective: To determine the difference, if any, in the placebo response when both perimenopausal and postmenopausal women are enrolled, compared with postmenopausal women alone, in a study assessing the efficacy of synthetic conjugated estrogen table

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29131165a0dd1d75d89c15431d83a0b8
https://doi.org/10.1080/cmt.4.1.19.27

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A 12-week clinical trial determining the efficacy of synthetic conjugated estrogens, A (SCE), in the treatment of vasomotor symptoms in menopausal women

Autor: R E, Stevens, K, Hanford, S, Wason, S L, Cusack, K V, Phelps

Publikováno v: International journal of fertility and women's medicine. 45(4)

To compare the clinical effects of a new oral synthetic conjugated estrogens, A (SCE), versus placebo in a clinically relevant population on the reduction in the mean number of moderate to severe vasomotor symptoms.A total of 120 healthy pre- and pos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5553a10ecd513f3ac416df1c59c05355
https://pubmed.ncbi.nlm.nih.gov/10997482

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