Zobrazeno 1 - 10
of 17
pro vyhledávání: '"K V, Laughlin"'
Autor:
K. V. Laughlin, James M. Mullin, Alejandro Peralta Soler, C. W. Marano, Hilary Clarke, Nicole Ginanni
Publikováno v:
Annals of the New York Academy of Sciences. 915:231-236
Exposure of LLC-PK1 epithelial cell cultures to phorbol ester tumor promoters causes immediate translocation of protein kinase C-alpha (PKC-alpha) from cytosolic to membrane-associated compartments. With a very similar time course, a dramatic and sus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f10351e0838e758838c5c207399d31
https://doi.org/10.1111/j.1749-6632.2000.tb05246.x
https://doi.org/10.1111/j.1749-6632.2000.tb05246.x
Autor:
James M. Mullin, Alejandro Peralta Soler, Bechara Kachar, Zoltan Szallasi, K. V. Laughlin, Cheryl E. K. Clarkin, Dan Rosson, R. Daniel Miller, J.A. Kampherstein
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
The Ca2+-independent δ-isoform of protein kinase C (PKC-δ) was overexpressed in LLC-PK1epithelia and placed under control of a tetracycline-responsive expression system. In the absence of tetracycline, the exogenous PKC-δ is expressed. Western imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba259d5f652b9c610ab7fd842f2e74d
https://doi.org/10.1152/ajpcell.1998.275.2.c544
https://doi.org/10.1152/ajpcell.1998.275.2.c544
Publikováno v:
Digestive Diseases and Sciences. 43:632-640
For rat distal colon, the transepithelialelectrical parameters, short circuit current(Iscc) and transepithelial electricalresistance (TER), respectively, measure nettransepithelial electrolyte transport activity and the barrier function of theepithel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a91285e4a50eca083a9f2f8e90b47ed
https://doi.org/10.1023/a:1018883712805
https://doi.org/10.1023/a:1018883712805
Autor:
A. Peralta Soler, K. V. Laughlin, James M. Mullin, R.D. Shurina, L. M. Russo, K. George, J.A. Kampherstein, Thomas G. O'Brien, Douglas Saladik
Publikováno v:
Experimental Cell Research. 227:12-22
Acute exposure (up to 4 h) of LLC-PK1 epithelial cell sheets to the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) causes a rapid decrease of transepithelial electrical resistance (TER) to less than 15% of initial value. As the TPA exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c4adfcdfee125bde64a276226f0c18
https://doi.org/10.1006/excr.1996.0244
https://doi.org/10.1006/excr.1996.0244
Autor:
James M. Mullin, L. M. Russo, Mary M Hagee, C. W. Marano, K. V. Laughlin, Suzanne Varimbi, Anne Guy
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1236(1):15-22
In addition to the concentrative, Na + -dependent inositol transport system demonstrated in many cell types, carrier-mediated, Na + -independent inositol transport is also shown to exist in LLC-PK 1 renal epithelia. Inhibition of inositol uptake in N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5454c648e923cf92ab41b29d400f74
Autor:
Jeffrey Bingham Smith, H. Clarke, K. V. Laughlin, George R. Pettit, N. Ginanni, James M. Mullin
Publikováno v:
Experimental cell research. 261(1)
The role of PKC-alpha in altered epithelial barrier permeability following the activation of PKC by TPA (12-O-tetradecanoyl phorbol 13-acetate) and bryostatin 1 in LLC-PK1 cells was investigated in this study. Like TPA, bryostatin 1 binds to and acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9c82f15cdc76d00bc7599e67c52cef
https://pubmed.ncbi.nlm.nih.gov/11082294
https://pubmed.ncbi.nlm.nih.gov/11082294
Autor:
James M. Mullin, Scott M. Goldman, Candace L. Trace, C. W. Marano, Lisa Igidbashian, Leah Ann Garulacan, George A Reichard, K. V. Laughlin, Francis P. Sutter
Publikováno v:
The Annals of thoracic surgery. 70(4)
Background. Tumor necrosis factor-a (TNF) has been implicated in the development of postoperative morbidity after cardiopulmonary bypass for myocardial revascularization. Despite their postulated roles as modulators of TNF bioavailability, soluble TN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9cdd9bc4eb9001da70faa3202433c8
https://pubmed.ncbi.nlm.nih.gov/11081891
https://pubmed.ncbi.nlm.nih.gov/11081891
Autor:
James M. Mullin, Alejandro Peralta Soler, R D Miller, K. V. Laughlin, David M. Klurfeld, N Z Carp
Publikováno v:
Carcinogenesis. 20(8)
Epithelial tissues act as barriers between two fluid compartments, and the epithelial barrier function is provided by the epithelial cells and the tight junctions (TJs) that connect them. We have shown previously that chronic treatment of a cultured
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c8de466a6324189498ff20acf34337
https://pubmed.ncbi.nlm.nih.gov/10426787
https://pubmed.ncbi.nlm.nih.gov/10426787
Publikováno v:
Cancer research. 58(8)
Protein kinase C activation leads to tight junctional leakiness and, consequently, to increased transepithelial (paracellular) solute flux across epithelial barriers. This leakiness is shown here to result in as much as a 20-fold increase in the tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fcbaf805c84c9e8f37259f8aceee17ee
https://pubmed.ncbi.nlm.nih.gov/9563475
https://pubmed.ncbi.nlm.nih.gov/9563475
Publikováno v:
Digestive diseases and sciences. 43(3)
For rat distal colon, the transepithelial electrical parameters, short circuit current (Iscc) and transepithelial electrical resistance (TER), respectively, measure net transepithelial electrolyte transport activity and the barrier function of the ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f082b3f3fbd2da1c44fe15c895c3aae3
https://pubmed.ncbi.nlm.nih.gov/9539661
https://pubmed.ncbi.nlm.nih.gov/9539661