Zobrazeno 1 - 2
of 2
pro vyhledávání: '"K V, Gleixner"'
Publikováno v:
European journal of clinical investigation. 38(11)
Systemic mastocytosis (SM) is a mast cell neoplasm in which neoplastic cells usually display the D816V-mutated variant of KIT. Cladribine (2CdA) and dasatinib are two drugs that counteract the in vitro growth of neoplastic mast cells in SM. However,
Autor:
K V, Gleixner, M, Mayerhofer, A, Vales, A, Gruze, G, Hörmann, S, Cerny-Reiterer, E, Lackner, E, Hadzijusufovic, H, Herrmann, A K, Iyer, M-T, Krauth, W F, Pickl, B, Marian, R, Panzer-Grümayer, C, Sillaber, H, Maeda, C, Zielinski, P, Valent
Publikováno v:
Current cancer drug targets. 9(5)
Heat shock protein 32 (Hsp32), also known as heme oxygenase-1 (HO-1), is a stress-related anti-apoptotic molecule, that has been implicated in enhanced survival of neoplastic cells and in drug-resistance. We here show that Hsp32 is expressed in most