Zobrazeno 1 - 10
of 458
pro vyhledávání: '"K Uyemura"'
Autor:
V E García, P A Sieling, J Gong, P F Barnes, K Uyemura, Y Tanaka, B R Bloom, C T Morita, R L Modlin
Publikováno v:
The Journal of Immunology. 159:1328-1335
TCR gamma delta T cells are considered important in the rapid immune response to intracellular infection. We investigated the early response of peripheral blood gamma delta T cells to the nonpeptide Ag isopentenyl pyrophosphate and to its synthetic a
Publikováno v:
The Journal of Immunology. 158:800-806
IL-15 is a novel cytokine with potent T cell growth factor activity. Here, we investigated the role of IL-15 in the human immune response to intracellular infection by studying patients leprosy. We found that IL-15 mRNA and protein were more strongly
Publikováno v:
Journal of Neuroscience Research. 45:571-587
We purified and characterized a novel axonal growth-related molecule, neurin-1, which is anchored to the surface membrane via a phosphatidylinositol (PI) linkage. This molecule was detected by a combination of phosphatidylinositol-specific phospholip
Publikováno v:
The Journal of Immunology. 155:2240-2247
Cytokines play a vital role in the host immune response by regulating the development and function of immunocompetent cells. To explore the possibility that tumors may alter the host response via release of immunomodulatory cytokines, we studied two
Autor:
P A Sieling, L Sakimura, K Uyemura, M Yamamura, J Oliveros, B J Nickoloff, T H Rea, R L Modlin
Publikováno v:
The Journal of Immunology. 154:2775-2783
The goal of the present study was to investigate the role of IL-7 in regulating immune responses to infection. Leprosy provides a model for understanding human immune responses to infection; the disease presents as a spectrum in which the clinical ma
Publikováno v:
The Journal of Immunology. 151:7095-7104
The mechanism of protective immunity and immunologic resistance against intracellular pathogens is believed to involve the activation of Ag-specific T cells. The T cells involved in protection/resistance to Leishmania can be studied using localized A
Publikováno v:
The Journal of Immunology. 149:1470-1475
Reactional states in leprosy are produced by different immunologic mechanisms and are responsible for a major component of tissue damage of the disease. Reversal reactions exhibit increased CD4 T cell infiltration in lesions and augmented cell-mediat
Publikováno v:
FEBS Letters. 307:361-366
Expression of major myelin glycoprotein P0 by PO cDNA transfection into C6 glioma cells promoted homophilic cell adhesion of the cells. After the dissociated cells were incubated for various times, the number of particles at each time point was measu
Publikováno v:
The Journal of Immunology. 148:1205-1211
T cells bearing gamma delta Ag receptors accumulate in the lesions of patients with localized American cutaneous leishmaniasis (LCL), and are thought to be involved in immunity to the parasite. To obtain clues as to the nature of the Ag recognized by
Autor:
M K, Song, M J, Rosenthal, A M, Song, K, Uyemura, H, Yang, M E, Ament, D T, Yamaguchi, E M, Cornford
Publikováno v:
British journal of pharmacology. 158(2)
We have previously shown that treatment with zinc plus cyclo-(His-Pro) (CHP) significantly stimulated synthesis of the insulin degrading enzyme and lowered plasma insulin and blood glucose levels, alongside improving oral glucose tolerance in genetic