Zobrazeno 1 - 10
of 67
pro vyhledávání: '"K U Malik"'
Publikováno v:
Journal of Lipid Research, Vol 27, Iss 5, Pp 517-522 (1988)
The objectives of this study were to characterize the effects of plasma lipoproteins on prostacyclin (PGI2) production by the Langendorff-perfused rabbit heart, and to determine the mechanism of lipoprotein-induced cardiac PGI2 production. PGI2 produ
Externí odkaz:
https://doaj.org/article/7f1e261765ab419b8a30926a235dc602
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 298(1)
SB203580 [4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole] is widely used as a specific inhibitor of p38 mitogen-activated protein kinase (MAPK). Here we report that SB203580, which blocked p38 kinase activation elicited by an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ab63c3e375c915f1818aed9c88834aac
https://pubmed.ncbi.nlm.nih.gov/11408559
https://pubmed.ncbi.nlm.nih.gov/11408559
Publikováno v:
The Journal of biological chemistry. 276(19)
Norepinephrine (NE) stimulates phospholipase D (PLD) through a Ras/MAPK pathway in rabbit vascular smooth muscle cells (VSMC). NE also activates calcium influx and calmodulin (CaM)-dependent protein kinase II-dependent cytosolic phospholipase A(2) (c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::61b6d12773ca3c1b09500929a2c3081a
https://pubmed.ncbi.nlm.nih.gov/11278912
https://pubmed.ncbi.nlm.nih.gov/11278912
Autor:
M M, Muthalif, J H, Parmentier, I F, Benter, N, Karzoun, A, Ahmed, Z, Khandekar, M Z, Adl, S, Bourgoin, K U, Malik
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 293(1)
Phospholipase D (PLD) activity is regulated by phosphatidylinositol 4,5-biphosphate, protein kinase C (PKC), ADP-ribosylation factor, and Rho. The present study was designed to investigate the mechanism of norepinephrine (NE)-mediated PLD activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3872ff9c0f6672501db06518ef2ec0a
https://pubmed.ncbi.nlm.nih.gov/10734178
https://pubmed.ncbi.nlm.nih.gov/10734178
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 284(2)
This study was conducted to determine the mechanism of arachidonic acid (AA) release elicited by phenylephrine (PHE) stimulation of alpha adrenergic receptor (AR), and its modulation by cyclic adenosine 3',5'-monophosphate (cAMP) in Rat-1 fibroblasts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d78d0bbf173754ee87310bc35ec38f03
https://pubmed.ncbi.nlm.nih.gov/9454800
https://pubmed.ncbi.nlm.nih.gov/9454800
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 284(1)
This study investigated the signal transduction mechanisms of angiotensin-(1-7) [Ang-(1-7)]- and Ang II-stimulated arachidonic acid (AA) release for prostaglandin (PG) production in rabbit aortic vascular smooth muscle cells. Ang II and Ang-(1-7) enh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b29aabf2fa7b037b3d7a757c99ef242
https://pubmed.ncbi.nlm.nih.gov/9435202
https://pubmed.ncbi.nlm.nih.gov/9435202
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 282(1)
The purpose of this study was to elucidate the mechanism by which acetylcholine (ACh) promotes prostacyclin (PGI2) production in cultured coronary endothelial cells (CEC) of the rabbit heart. ACh-induced production of PGI2, measured as immunoreactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b2b955a1e1367b1e2fa55cfe581fd9e
https://pubmed.ncbi.nlm.nih.gov/9223547
https://pubmed.ncbi.nlm.nih.gov/9223547
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(3)
Activation of beta adrenergic receptors in the isolated rabbit heart by catecholamines stimulates prostacyclin (PGI2) synthesis, which is inhibited by adenosine 3'5'-cyclic monophosphate (cAMP). The purpose of this study was to determine if activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b969b0930e4caa4245c72cbd6bc4dff
https://pubmed.ncbi.nlm.nih.gov/9190834
https://pubmed.ncbi.nlm.nih.gov/9190834
Publikováno v:
Molecular pharmacology. 50(5)
We previously showed that acetylcholine (ACh) stimulates production of prostacyclin, measured as immunoreactive 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha), in coronary endothelial cells (CEC) of rabbit heart by increasing influx of extracellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c72fc762e9f04e3ca827b0c5575c0d6
https://pubmed.ncbi.nlm.nih.gov/8913345
https://pubmed.ncbi.nlm.nih.gov/8913345
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 278(2)
The purpose of the present study was to determine the possible interaction of cyclic AMP (cAMP) and the synthesis of prostacyclin [measured as immunoreactive 6-keto-prostaglandin (PG)F1 alpha] elicited by the beta adrenergic receptor agonist isoprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68a3460281a22bac3c9e6127ca17a3db
https://pubmed.ncbi.nlm.nih.gov/8768695
https://pubmed.ncbi.nlm.nih.gov/8768695