Zobrazeno 1 - 10
of 35
pro vyhledávání: '"K U, Schallreuter"'
Autor:
K U Schallreuter, M M A E L Salem
Publikováno v:
Der Hautarzt. 61:578-585
Vitiligo occurs in Northern Europe in one of 200 people. The disease can cause significant psychological stress for the affected individual. These patients generate and accumulate massive amounts of H(2)O(2)- and peroxynitrite in the epidermal compar
Autor:
K U Schallreuter, K R Lemke
Publikováno v:
Der Hautarzt. 45:783-786
A 19-year-old male patient with chronic cutaneous leishmania is was treated topically with paromomycin sulphate (15%) and methylbenzethonium chloride (12%) in petrolatum album. After application twice daily for two periods of 32 and 44 days the lesio
Autor:
K U, Schallreuter, M M A E L, Salem
Publikováno v:
Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete. 61(7)
Vitiligo occurs in Northern Europe in one of 200 people. The disease can cause significant psychological stress for the affected individual. These patients generate and accumulate massive amounts of H(2)O(2)- and peroxynitrite in the epidermal compar
Publikováno v:
Journal of inherited metabolic disease. 32(1)
Patients with vitiligo accumulate up to 10(-3) mol/L concentrations of H(2)O(2) in their epidermis, which in turn affects many metabolic pathways in this compartment, including the synthesis and recycling of the cofactor (6R)-L-erythro-5,6,7,8-tetrah
Autor:
Lübeck Ralf Paus, K. U. Schallreuter, P. Bahadoran, M. Picardo, A. Slominski, Y. E. Elassiuty, E. H. Kemp, C. Giachino, J. B. Liu, R. M. Luiten, T. Lambe, I. C. Le Poole, I. Dammak, H. Onay, M. A. Zmijewski, M. L. Dell’Anna, M. P. Zeegers, R. J. Cornall, R. Paus, J. P. Ortonne, W. Westerhof
Publikováno v:
Experimental dermatology, 17(2). Wiley-Blackwell
Experimental Dermatology, 17(2). Wiley
Experimental Dermatology, 17(2). Wiley
The pathobiology of vitiligo has been hotly disputed for as long as one remembers, and has been a magnet for endless speculation. Evidently, the different schools of thought--ranging, e.g. from the concept that vitiligo essentially is a free-radical
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 52(2)
Human epidermal keratinocytes and melanocytes express proopiomelanocortins (POMC) and all of the enzymes for POMC processing, i.e. prohormone convertases PC-1 and PC-2 including the regulatory protein 7B2. In melanocytes POMC processing also occurs i
Autor:
H Rokos, K U Schallreuter
Publikováno v:
Chemistry and Biology of Pteridines and Folates ISBN: 9781461353171
In Vitiligo the epidermal pteridine metabolism is perturbed concomitantly with a mM build-up of H2O2 in the epidermis of patients. The epidermal de novo and recycling biosynthetic pathway of tetrahydrobiopterin shows increased GTP-CH I activity, redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ba57bc7fbc689870b932ab89592bdbd
https://doi.org/10.1007/978-1-4615-0945-5_9
https://doi.org/10.1007/978-1-4615-0945-5_9
Publikováno v:
The Journal of pathology. 191(4)
This paper provides evidence that melanocytes are still present in the depigmented epidermis of patients with vitiligo even after stable disease of 25 years' duration. Melanocyte cultures were successfully established from depigmented epidermal sucti
Autor:
K U, Schallreuter
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 45(7)
It has been recognised that the active transport of L-phenylalanine and its autocrine turnover to L-tyrosine via phenylalanine hydroxylase in the cytosol of epidermal melanocytes provides the majority of the L-tyrosine pool for melanogenesis. In this
Publikováno v:
The British journal of dermatology. 141(2)
It has recently been shown that patients with vitiligo can accumulate epidermal hydrogen peroxide (H2O2) in association with low catalase levels. This study examined serum selenium levels and blood glutathione peroxidase activities in 61 patients and