Výsledky vyhledávání

INDUCTION OF CHRONIC AUTOIMMUNE ARTHRITIS IN DBA/1 MICE BY ORAL ADMINISTRATION OF TYPE II COLLAGEN AND ESCHERICHIA COLl LIPOPOLYSACCHARIDE

Autor: M. A. Cremer, H. Miyahara, K Terato, X J Ye, Marie M. Griffiths

Publikováno v: Rheumatology. 35:828-838

We have developed a new model of autoimmune arthritis in DBA/1 mice by feeding chick type II collagen (CII) for 2-3 week intervals over a 15 week period. Clinically evident arthritis occurred in 8/10 mice receiving native CII (nCII; 100 micrograms/mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589a781e6fc662f6e354fa2ca07f9f76
https://doi.org/10.1093/rheumatology/35.9.828

Zobrazit plný text záznamu

Type XI collagen-induced arthritis in the Lewis rat. Characterization of cellular and humoral immune responses to native types XI, V, and II collagen and constituent alpha-chains

Autor: M A Cremer, X J Ye, K Terato, S W Owens, J M Seyer, A H Kang

Publikováno v: The Journal of Immunology. 153:824-832

Autoimmune arthritis can be induced in rats by immunization with cartilage-specific types II and XI collagen. Type XI collagen is composed of alpha 1(XI), alpha 2(XI), and alpha 3(XI) chains, in which alpha 3(XI) is essentially identical to alpha 1(I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ac10b4e62623d492a1cf94af2a3b2f6
https://doi.org/10.4049/jimmunol.153.2.824

Zobrazit plný text záznamu

Characterization of the T cell determinants in the induction of autoimmune arthritis by bovine alpha 1(II)-CB11 in H-2q mice

Autor: D D Brand, L K Myers, K Terato, K B Whittington, J M Stuart, A H Kang, E F Rosloniec

Publikováno v: The Journal of Immunology. 152:3088-3097

Collagen-induced arthritis (CIA) is an experimental autoimmune disease elicited in genetically susceptible strains of mice by immunization with heterologous type II collagen. This experimental disease is mediated by the immune response of both T and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b79afe7c57cd6d4bbc01205642c06114
https://doi.org/10.4049/jimmunol.152.6.3088

Zobrazit plný text záznamu

T cell epitopes of type II collagen that regulate murine collagen-induced arthritis

Autor: L K Myers, J M Seyer, J M Stuart, K Terato, C S David, A H Kang

Publikováno v: The Journal of Immunology. 151:500-505

Chick type II collagen (CII), a protein commonly found in joint cartilage, induces an autoimmune arthritis when administered to susceptible strains of mice. A cyanogen bromide fragment of CII, CB11, contains the requisite epitopes critical for induci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39952d05c6f9e324810ff21fb4f82054
https://doi.org/10.4049/jimmunol.151.1.500

Zobrazit plný text záznamu

Characterization of a tolerogenic T cell epitope of type II collagen and its relevance to collagen-induced arthritis

Autor: L K Myers, K Terato, J M Seyer, J M Stuart, A H Kang

Publikováno v: The Journal of Immunology. 149:1439-1443

A synthetic peptide representing sequences of type II collagen, (CII 245-270), has previously been used to induce tolerance and suppress arthritis in DBA/1 mice. To determine important residues, a series of peptides, each containing one or two site-d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d4c114a32ad7017ef7677712c16f1ec6
https://doi.org/10.4049/jimmunol.149.4.1439

Zobrazit plný text záznamu

Collagen-induced arthritis in rats. Examination of the epitope specificities of circulating and cartilage-bound antibodies produced by outbred and inbred rats using cyanogen bromide-derived peptides purified from heterologous and homologous type II collagens

Autor: M A Cremer, K Terato, W C Watson, M M Griffiths, A S Townes, A H Kang

Publikováno v: The Journal of Immunology. 149:1045-1053

To determine the number and location of antibody binding epitopes on type II collagen, outbred and inbred rats were immunized with chick, bovine, human, and rat type II collagen (CII, BII, HII, and RII); all sera were assayed for reaction with a pane

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f12b397890f92640254bf7a452c899fd
https://doi.org/10.4049/jimmunol.149.3.1045

Zobrazit plný text záznamu

Induction of arthritis with monoclonal antibodies to collagen

Autor: K Terato, K A Hasty, R A Reife, M A Cremer, A H Kang, J M Stuart

Publikováno v: The Journal of Immunology. 148:2103-2108

mAb were developed from DBA/1 mice immunized with chick type II collagen. A total of 69 IgG antibodies was isolated and characterized. The majority (36%) reacted with a CNBr-derived peptide CB11 previously identified as containing a major immunogenic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::103bc85259ae4db4e778a5b5181f70eb
https://doi.org/10.4049/jimmunol.148.7.2103

Zobrazit plný text záznamu

Immunity to type XI collagen in mice. Evidence that the alpha 3(XI) chain of type XI collagen and the alpha 1(II) chain of type II collagen share arthritogenic determinants and induce arthritis in DBA/1 mice

Autor: M A Cremer, K Terato, J M Seyer, W C Watson, G O O'Hagan, A S Townes, A H Kang

Publikováno v: The Journal of Immunology. 146:4130-4137

To determine whether native bovine type XI collagen (BXI) is arthritogenic, five strains of inbred mice were immunized with BXI/CFA. Arthritis was not observed in any of these strains, though it was prevalent in DBA/1 and B10.RIII controls immunized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dcbcb613ed30a60ea8d7a490d8dbb256
https://doi.org/10.4049/jimmunol.146.12.4130

Zobrazit plný text záznamu

Analysis of Type II Collagen Reactive T Cells in the Mouse

Autor: K. Terato, M. A. Cremer, Harald Burkhardt, M. Andersson, Rikard Holmdahl

Publikováno v: Scandinavian Journal of Immunology. 33:505-510

The specificity of the recognition of type II collagen (CII) by T cells in the DBA/l mouse was analysed using fragments of chick and rat CII obtained by cyanogen bromide (CB) cleavage. Firstly, DBA/l mice were immunized with chick CB fragments 5, 8,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ac32fa9d2142b93b167f917d8fca67
https://doi.org/10.1111/j.1365-3083.1991.tb02520.x

Zobrazit plný text záznamu

Human HLA-DR beta gene hypervariable region homology in the biobreeding BB rat: selection of the diabetic-resistant subline as a rheumatoid arthritis research tool to characterize the immunopathologic response to human type II collagen

Autor: W C Watson, J P Thompson, K Terato, Andrew H. Kang, M A Cremer

Publikováno v: The Journal of Experimental Medicine

Collagen arthritis (CA), an autoimmune model of rheumatoid arthritis (RA), has been studied in various animals. However, it has not been studied in an animal with a genetic background relevant to RA. We selected rats from a diabetic-resistant (DR) su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265c229e898f670f70dcfe3bc9928652
https://doi.org/10.1084/jem.172.5.1331

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání