Zobrazeno 1 - 10
of 464
pro vyhledávání: '"K Tamm"'
Autor:
Catherine A. Doyle, Gregory W. Busey, Wesley H. Iobst, Volker Kiessling, Chloe Renken, Hansa Doppalapudi, Marta E. Stremska, Mohan C. Manjegowda, Mohd Arish, Weiming Wang, Shardul Naphade, Joel Kennedy, Louis-Marie Bloyet, Cassandra E. Thompson, Paul W. Rothlauf, Eric J. Stipes, Sean P. J. Whelan, Lukas K. Tamm, Alex J. B. Kreutzberger, Jie Sun, Bimal N. Desai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The majority of viruses classified as pandemic threats are enveloped viruses which enter the cell through receptor-mediated endocytosis and take advantage of endosomal acidification to activate their fusion machinery. Here we report that the
Externí odkaz:
https://doaj.org/article/dee6605d5bdc48a684b5ee4df122fe09
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Ebola virus (EBOV) causes a hemorrhagic fever with fatality rates up to 90%. The EBOV entry process is complex and incompletely understood. Following attachment to host cells, EBOV is trafficked to late endosomes/lysosomes where its glycopro
Externí odkaz:
https://doaj.org/article/520065fb1dde4d3982eafd6a4d0f4c31
Autor:
Robert E. Coffman, Katelyn N. Kraichely, Alex J. B. Kreutzberger, Volker Kiessling, Lukas K. Tamm, Dixon J. Woodbury
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Alcohol affects many neuronal proteins that are upstream or down-stream of synaptic vesicle fusion and neurotransmitter release. Less well studied is alcohol’s effect on the fusion machinery including SNARE proteins and lipid membranes. Using a SNA
Externí odkaz:
https://doaj.org/article/362d209278d941b8b9d3d30b5a4cda24
Autor:
Sarah B. Nyenhuis, Nakul Karandikar, Volker Kiessling, Alex J. B. Kreutzberger, Anusa Thapa, Binyong Liang, Lukas K. Tamm, David S. Cafiso
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Synaptotagmin 1 (Syt1) is the calcium sensor for fast synchronous neurotransmitter release but the mechanism by which it functions is still under debate. Here, the authors combine EPR measurements and functional studies and observe that different fac
Externí odkaz:
https://doaj.org/article/81777fc5abd14f21a6ee0ae5308e9f0f
Publikováno v:
Acta Agriculturae Scandinavica. Section B, Soil and Plant Science, Vol 70, Iss 1, Pp 31-38 (2020)
Acidification is one of the recommended treatments to reduce NH3 emissions from animal slurry. Economically, the sulphuric acid is the most feasible agent to lower slurry pH. This study explains the impact of acidified slurry on soil and crop in a le
Externí odkaz:
https://doaj.org/article/d578b8be381b4cf3b2837681b4f80d9a
Publikováno v:
Сельскохозяйственные машины и технологии, Vol 13, Iss 5, Pp 4-10 (2019)
Ammonia emissions are a worldwide major environmental concern. In 2017, ammonia emissions in the European part of Russia amounted to 80.9 thousand tons, of which up to 56.9 thousand tons came from agriculture. The main source of ammonia in this secto
Externí odkaz:
https://doaj.org/article/bec104d83f2645cab9a8646e3745012b
Autor:
Alex J. B. Kreutzberger, Volker Kiessling, Christopher Stroupe, Binyong Liang, Julia Preobraschenski, Marcelo Ganzella, Mark A. B. Kreutzberger, Robert Nakamoto, Reinhard Jahn, J. David Castle, Lukas K. Tamm
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Regulated exocytosis of neuronal synaptic vesicles is substantially faster than that of endocrine dense core vesicles despite similar molecular machineries. Here authors compare SNARE-mediated fusion of purified synaptic vesicles with insulin vesicle
Externí odkaz:
https://doaj.org/article/4a79a606ae254e35b295a19f8e1dafc2
Autor:
Amanda E. Ward, Daria Sokovikova, M. Neal Waxham, Frederick A. Heberle, Ilya Levental, Kandice R. Levental, Volker Kiessling, Judith M. White, Lukas K. Tamm
Publikováno v:
ACS Infectious Diseases. 9:773-784
The host restriction factor, Serinc5, incorporates into budding HIV particles and inhibits their infection by an incompletely understood mechanism. We have previously reported that Serinc5 but not its paralogue, Serinc2, blocks HIV cell entry by memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379eb6b725c39b57432eb376bdd1a0d6
https://doi.org/10.1021/acsinfecdis.2c00478
https://doi.org/10.1021/acsinfecdis.2c00478
Autor:
Adishesh K Narahari, Alex JB Kreutzberger, Pablo S Gaete, Yu-Hsin Chiu, Susan A Leonhardt, Christopher B Medina, Xueyao Jin, Patrycja W Oleniacz, Volker Kiessling, Paula Q Barrett, Kodi S Ravichandran, Mark Yeager, Jorge E Contreras, Lukas K Tamm, Douglas A Bayliss
Publikováno v:
eLife, Vol 10 (2021)
Pannexin 1 (Panx1) is a membrane channel implicated in numerous physiological and pathophysiological processes via its ability to support release of ATP and other cellular metabolites for local intercellular signaling. However, to date, there has bee
Externí odkaz:
https://doaj.org/article/c4cc7f86651745e69bab242b4d3678d0
Autor:
Laura Odongo, Kaneil K. Zadrozny, William E. Diehl, Jeremy Luban, Judith M. White, Barbie K. Ganser-Pornillos, Lukas K. Tamm, Owen Pornillos
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 79:45-50
Niemann–Pick C1 protein (NPC1) is a membrane protein that primarily resides in late endosomes and lysosomes, and plays an important role in cholesterol homeostasis in the cell. The second luminal domain of NPC1 (NPC1-C) serves as the intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::093c95ddf74108bee21047c87723fb60
https://doi.org/10.1107/s2053230x23000705
https://doi.org/10.1107/s2053230x23000705