Zobrazeno 1 - 10
of 14
pro vyhledávání: '"K T Miyasaki"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:2710-2715
Actinobacillus actinomycetemcomitans and Capnocytophaga spp. are gram-negative bacteria implicated in the etiology of periodontal disease (particularly in individuals with neutrophil defects) and life-threatening systemic infections. They are resista
Publikováno v:
The Journal of Immunology. 151:6291-6301
Microbiostatic mechanisms may contribute substantially to host defense against infection by certain microbes. We studied the candidastatic activity of human neutrophils, neutrophil cytosol, and neutrophil-derived "calprotectin," a cytosolic protein c
Publikováno v:
Journal of leukocyte biology. 70(1)
Calprotectin is an abundant cytosolic protein complex of human neutrophils with in vitro extracellular antimicrobial activity. Studies suggest that calprotectin may be actively secreted from intact HL-60 cells and that it can be translocated to polym
Publikováno v:
Oral microbiology and immunology. 15(4)
The bactericidal activity of synthetic LL-37, a cathelicidin, was assessed against Actinobacillus actinomycetemcomitans (three strains) and Capnocytophaga spp. (three strains). All strains were sensitive to LL-37, and exhibited 99% effective dose of
Autor:
K T, Miyasaki, R I, Lehrer
Publikováno v:
International journal of antimicrobial agents. 9(4)
Small, cysteine-rich, beta-sheet peptide antibiotics are found throughout the Animalia. Though broad spectrum in potential, they may exert selective antimicrobial effects under certain conditions. We have explored the antimicrobial properties of two
Publikováno v:
Advances in dental research. 9(1)
Cathepsin G is a neutral serine protease of the granzyme B family which is found in human PMN, cells known to be important in the defense of the periodontium against periodontal bacteria. We propose that cathepsin G serves as a "pro-antibiotic" conta
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 151(11)
Microbiostatic mechanisms may contribute substantially to host defense against infection by certain microbes. We studied the candidastatic activity of human neutrophils, neutrophil cytosol, and neutrophil-derived "calprotectin," a cytosolic protein c
Autor:
A L Bodeau, K T Miyasaki
The Capnocytophaga are inhabitants of the hypoxic human gingival crevice that are normally prevented by neutrophils from causing periodontal and systemic infection. To identify potential nonoxidative bactericidal mechanisms against Capnocytophaga wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e5f0ef432d514a66ba9ae87dcfef84f
https://europepmc.org/articles/PMC295241/
https://europepmc.org/articles/PMC295241/
Publikováno v:
Infection and Immunity. 53:161-165
Actinobacillus actinomycetemcomitans is a facultative gram-negative coccobacillus associated with periodontal disease and nonoral infections. This organism is resistant to serum bactericidal mechanisms but is nevertheless killed by human neutrophils
Publikováno v:
Archives of Biochemistry and Biophysics. 246:751-764
Myeloperoxidase (MPO) is an enzyme found in the azurophil granules of neutrophils. Cation-exchange chromatography on carboxymethyl-cellulose previously has been used to demonstrate the heterogeneity of the peroxidase enzymes isolated from human neutr