Výsledky vyhledávání - "K T, Goldsmith"

E1A RNA transcripts amplify adenovirus-mediated tumor reduction

Autor: L D, Dion, K T, Goldsmith, T V, Strong, G, Bilbao, D T, Curiel, R I, Garver

Publikováno v: Gene therapy. 3(11)

Previous work by this group has established that E1-defective, recombinant adenoviruses can be replication-enabled by the codelivery of a plasmid encoding the deleted E1 functions, a strategy now designated conditional replication-enablement system f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::68b1f8ab38bf736076ea94396e5fc770
https://pubmed.ncbi.nlm.nih.gov/9044743

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Quantitative and in vivo activity of adenoviral-producing cells made by cotransduction of a replication-defective adenovirus and a replication-enabling plasmid

Autor: L D, Dion, K T, Goldsmith, R I, Garver

Publikováno v: Cancer gene therapy. 3(4)

Achieving limited recombinant viral replication may provide a means of amplifying viral-mediated gene transfer in vivo. We have previously shown that cotransduction of an E1-defective adenovirus with a plasmid containing the deleted E1 functions into

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c7e1ab74e534f089ccfd97c73b392cde
https://pubmed.ncbi.nlm.nih.gov/8853547

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Strategy for achieving selective killing of carcinomas

Autor: R I, Garver, K T, Goldsmith, B, Rodu, P C, Hu, E J, Sorscher, D T, Curiel

Publikováno v: Gene therapy. 1(1)

Carcinomas are malignancies derived from epithelial cells that frequently respond poorly to conventional chemotherapy. Selective expression or transduction of toxin genes to carcinomas, i.e. molecular chemotherapy, may offer important advantages over

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::53a55ebf6e3faff8f455889b145ddee7
https://pubmed.ncbi.nlm.nih.gov/7584059

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Action of a phorbol ester on B-cells: potentiation of stimulant-induced electrical activity

Autor: K. T. Goldsmith, C. S. Pace

Publikováno v: American Journal of Physiology-Cell Physiology. 248:C527-C534

The possible role of protein kinase c in regulating the electrical events in the B-cell plasma membrane was examined by using the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA), a known activator of this enzyme. TPA has been found to enhan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1accf63090f5f741741c8a39679c2f
https://doi.org/10.1152/ajpcell.1985.248.5.c527

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