Zobrazeno 1 - 10
of 28
pro vyhledávání: '"K T, Bunce"'
Autor:
Patrick P.A. Humphrey, C. J. Grossman, J. W. F. Whitehead, Jeremy D. Gale, A.W. Oxford, K. T. Bunce
Publikováno v:
British Journal of Pharmacology. 111:332-338
1. The 5-HT4 receptor has only recently been identified but has yet to be cloned. This paper describes the pharmacology of a potent and selective 5-HT4 receptor antagonist, GR113808, which will be useful in the further characterization of this recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3facd9eedb4984787207d1f05633f02
https://doi.org/10.1111/j.1476-5381.1994.tb14064.x
https://doi.org/10.1111/j.1476-5381.1994.tb14064.x
Autor:
C.F. Spraggs, K. T. Bunce
Publikováno v:
British Journal of Pharmacology. 101:889-895
1. The receptors that mediate stimulation of anion secretion by prostanoids in isolated preparations of guinea-pig gastric and ileal mucosa have been compared by use of selective prostanoid agonists and antagonists. 2. In gastric mucosa, the relative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f699aa12bfa258ccf0a360ac2d641ebb
https://doi.org/10.1111/j.1476-5381.1990.tb14176.x
https://doi.org/10.1111/j.1476-5381.1990.tb14176.x
Autor:
J. Burridge, A. Butler, C.J. Elswood, K. T. Bunce, M.B. Tyers, Gavin J. Kilpatrick, S.J. Ireland
Publikováno v:
British Journal of Pharmacology. 101:591-598
1. The pharmacological characterization of the 5-HT3 receptors in guinea-pig isolated tissues is described. The tissues used were ileum (longitudinal muscle-myenteric plexus), colon and vagus nerve. The guinea-pig isolated colon is a novel preparatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9681dc5963ff31d1676170c598ac13f5
https://doi.org/10.1111/j.1476-5381.1990.tb14126.x
https://doi.org/10.1111/j.1476-5381.1990.tb14126.x
Autor:
C J Elswood, K T Bunce
Publikováno v:
Journal of Pharmacy and Pharmacology. 44:264-266
5-Hydroxytryptamine (5-HT) induced concentration-related relaxations (EC50 = 9·1 μm) of guinea-pig proximal colon pretreated with ketanserin (1 μm) and ondansetron (10 μm). This 5-HT-induced effect was neuronally mediated since it was blocked by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91eed013a928b286b94dbd3154a4475
https://doi.org/10.1111/j.2042-7158.1992.tb03597.x
https://doi.org/10.1111/j.2042-7158.1992.tb03597.x
Autor:
P. P. Humphrey, K. T. Bunce
Publikováno v:
BMJ (Clinical research ed.). 305(6860)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1fc2571af297359c38720c3096c9df
https://pubmed.ncbi.nlm.nih.gov/1458130
https://pubmed.ncbi.nlm.nih.gov/1458130
Autor:
K T, Bunce, N M, Clayton, R A, Coleman, E W, Collington, H, Finch, J M, Humphray, P P, Humphrey, J J, Reeves, R L, Sheldrick, R, Stables
Publikováno v:
Advances in prostaglandin, thromboxane, and leukotriene research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1854871fb1ce8d8d8932dc298c766ffc
https://pubmed.ncbi.nlm.nih.gov/1825574
https://pubmed.ncbi.nlm.nih.gov/1825574
Publikováno v:
Agents and Actions. 11:167-170
Gastric mucosal lesions were produced in rats by dosing orally with aspirin, 300 mg/kg. Predosing orally with either ranitidine or cimetidine inhibited this lesion formation; the respective ED50 values were 0.8 and 3.9 mg/kg p.o. Oral ranitidine also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44d44862b851dcc082f5dbd34bfd32d
https://doi.org/10.1007/bf01991491
https://doi.org/10.1007/bf01991491
Autor:
K. T. Bunce, C.F. Spraggs
Publikováno v:
British Journal of Pharmacology. 77:469-475
1 The effect of chlorpromazine (Cpz) on the net fluxes of water and sodium in the ileum and colon has been studied in the anaesthetized rat. 2 Under control conditions both the ileum and colon absorbed water and sodium. Cpz (100 mumol/kg, s.c.) had n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6846481ede4dd2f7cd245caa0399bbcc
https://doi.org/10.1111/j.1476-5381.1982.tb09320.x
https://doi.org/10.1111/j.1476-5381.1982.tb09320.x
Publikováno v:
Agents and Actions. 11:160-164
The H2-receptor antagonists ranitidine and cimetidine were tested against gastric secretory dose-response curves to histamine, pentagastrin and bethanechol in the Heidenhain-pouch dog. Histamine-induced gastric secretion was antagonized in a competit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3474d8a426072f70ab12d0f9ad9a637
https://doi.org/10.1007/bf01991489
https://doi.org/10.1007/bf01991489
Autor:
M E Parsons, K T Bunce
Publikováno v:
The Journal of Physiology. 258:453-465
1. An isolated whole stomach preparation from immature rats is described. The lumen of the stomach was perfused and the hydrogen ion activity of the perfusate recorded continuously. 2. The mean basal acid secretion before stimulation was 4-19 +/- 0-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e7764bcfe8c9cf140faf571817a19c
https://doi.org/10.1113/jphysiol.1976.sp011430
https://doi.org/10.1113/jphysiol.1976.sp011430