Zobrazeno 1 - 10
of 35
pro vyhledávání: '"K Shanebeck"'
Autor:
L S Park, D. J. Friend, R. DuBose, Dirk M. Anderson, K. Shanebeck, J. G. Giri, M Ahdieh, A. Loomis, David Cosman, S Kumaki
Publikováno v:
The EMBO Journal. 14:3654-3663
Interleukin-15 (IL-15) is a novel cytokine of the four-helix bundle family which shares many biological activities with IL-2, probably due to its interaction with the IL-2 receptor beta and gamma (IL-2R beta and gamma c) chains. We report here the ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e0a17cf3352f5d18ca759faed36e0b
https://doi.org/10.1002/j.1460-2075.1995.tb00035.x
https://doi.org/10.1002/j.1460-2075.1995.tb00035.x
Autor:
J G Giri, J Wells, S K Dower, C E McCall, R N Guzman, J Slack, T A Bird, K Shanebeck, K H Grabstein, J E Sims
Publikováno v:
The Journal of Immunology. 153:5802-5809
Two types of cellular IL-1Rs have been characterized and cloned from both human and murine sources. The type II IL-1R has a very short cytoplasmic domain and does not seem to participate in IL-1 signaling. We demonstrate that type II IL-1Rs are relea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::152e718ee5a733425125233e6b832c4c
https://doi.org/10.4049/jimmunol.153.12.5802
https://doi.org/10.4049/jimmunol.153.12.5802
Autor:
K H Grabstein, C R Maliszewski, K Shanebeck, T A Sato, M K Spriggs, W C Fanslow, R J Armitage
Publikováno v:
The Journal of Immunology. 150:3141-3147
Our study demonstrates the central role for the murine CD40 ligand and IL-2 in contact-dependent T cell help for Ag-specific primary antibody responses in vitro. Helper T cell clones were found to express CD40 ligand after activation with CD3 mAb. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fd7872986e53e581e7018283036dd5a
https://doi.org/10.4049/jimmunol.150.8.3141
https://doi.org/10.4049/jimmunol.150.8.3141
Publikováno v:
The Journal of Immunology. 144:3015-3020
The regulation of murine T cell proliferation by IL-7 was investigated. Highly purified resting splenic T cells were induced to proliferate in a short term assay by IL-7 in the presence of the comitogen, Con A. The proliferation of these resting T ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c6c188abd4d803a2cc1eed41fcfc780
https://doi.org/10.4049/jimmunol.144.8.3015
https://doi.org/10.4049/jimmunol.144.8.3015
Autor:
J Eisenman, L S Park, Dirk M. Anderson, David Cosman, K H Grabstein, S Kumaki, A Namen, M Ahdieh, K. Shanebeck, J. G. Giri
Publikováno v:
The EMBO journal. 13(12)
We have recently cloned a novel cytokine, IL-15, with shared bioactivities but no sequence homology with IL-2. We found high affinity IL-15 binding to many cell types, including cells of non-lymphoid origin. Analysis of IL-15 interaction with subunit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f1a7ef608cf4ce49523fc33ae3d822
https://pubmed.ncbi.nlm.nih.gov/8026467
https://pubmed.ncbi.nlm.nih.gov/8026467
Autor:
J G Giri, T A Bird, Mark R. Alderson, K Shanebeck, Alberto Mantovani, Francesco Colotta, Jennifer L. Slack, John E. Sims, Fabio Re, M A Gayle
Two receptors for the proinflammatory cytokine interleukin 1 (IL-1) have been cloned and characterized biochemically. While it has been well established that the type I (80-kDa) IL-1 receptor can mediate responses to IL-1, the function of the type II
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b63904a117ece7d0b8e7f974bfe6837
https://europepmc.org/articles/PMC46886/
https://europepmc.org/articles/PMC46886/
Akademický článek
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Publikováno v:
The Journal of Experimental Medicine
Recombinant granulocyte/macrophage colony-stimulating factors (rGM-CSF) of mouse and human origins activated macrophages of the homologous species to inhibit the replication of the protozoan parasite T. cruzi. Activation could be induced with 10-100
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad88864471caffcef02de82883ee4f8
https://doi.org/10.1084/jem.166.6.1734
https://doi.org/10.1084/jem.166.6.1734
Akademický článek
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Akademický článek
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