Zobrazeno 1 - 10
of 108
pro vyhledávání: '"K Shanebeck"'
Autor:
L S Park, D. J. Friend, R. DuBose, Dirk M. Anderson, K. Shanebeck, J. G. Giri, M Ahdieh, A. Loomis, David Cosman, S Kumaki
Publikováno v:
The EMBO Journal. 14:3654-3663
Interleukin-15 (IL-15) is a novel cytokine of the four-helix bundle family which shares many biological activities with IL-2, probably due to its interaction with the IL-2 receptor beta and gamma (IL-2R beta and gamma c) chains. We report here the ch
Autor:
J G Giri, J Wells, S K Dower, C E McCall, R N Guzman, J Slack, T A Bird, K Shanebeck, K H Grabstein, J E Sims
Publikováno v:
The Journal of Immunology. 153:5802-5809
Two types of cellular IL-1Rs have been characterized and cloned from both human and murine sources. The type II IL-1R has a very short cytoplasmic domain and does not seem to participate in IL-1 signaling. We demonstrate that type II IL-1Rs are relea
Autor:
K H Grabstein, C R Maliszewski, K Shanebeck, T A Sato, M K Spriggs, W C Fanslow, R J Armitage
Publikováno v:
The Journal of Immunology. 150:3141-3147
Our study demonstrates the central role for the murine CD40 ligand and IL-2 in contact-dependent T cell help for Ag-specific primary antibody responses in vitro. Helper T cell clones were found to express CD40 ligand after activation with CD3 mAb. Me
Publikováno v:
The Journal of Immunology. 144:3015-3020
The regulation of murine T cell proliferation by IL-7 was investigated. Highly purified resting splenic T cells were induced to proliferate in a short term assay by IL-7 in the presence of the comitogen, Con A. The proliferation of these resting T ce
Autor:
J Eisenman, L S Park, Dirk M. Anderson, David Cosman, K H Grabstein, S Kumaki, A Namen, M Ahdieh, K. Shanebeck, J. G. Giri
Publikováno v:
The EMBO journal. 13(12)
We have recently cloned a novel cytokine, IL-15, with shared bioactivities but no sequence homology with IL-2. We found high affinity IL-15 binding to many cell types, including cells of non-lymphoid origin. Analysis of IL-15 interaction with subunit
Autor:
J G Giri, T A Bird, Mark R. Alderson, K Shanebeck, Alberto Mantovani, Francesco Colotta, Jennifer L. Slack, John E. Sims, Fabio Re, M A Gayle
Two receptors for the proinflammatory cytokine interleukin 1 (IL-1) have been cloned and characterized biochemically. While it has been well established that the type I (80-kDa) IL-1 receptor can mediate responses to IL-1, the function of the type II
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b63904a117ece7d0b8e7f974bfe6837
https://europepmc.org/articles/PMC46886/
https://europepmc.org/articles/PMC46886/
Akademický článek
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Publikováno v:
The Journal of Experimental Medicine
Recombinant granulocyte/macrophage colony-stimulating factors (rGM-CSF) of mouse and human origins activated macrophages of the homologous species to inhibit the replication of the protozoan parasite T. cruzi. Activation could be induced with 10-100
Autor:
Yang, Jing1 (AUTHOR), Wang, Kefan2 (AUTHOR), Zhang, Shanyu2 (AUTHOR), Zheng, Xiaocui1 (AUTHOR), Cui, Tongxiao1 (AUTHOR), Yang, Xian2 (AUTHOR), Liu, Yao2 (AUTHOR), Lu, Di1 (AUTHOR), Wang, Yuqin2 (AUTHOR), Tian, Xiao1 (AUTHOR), Zhang, Panke2 (AUTHOR), Huang, Shuo2,3 (AUTHOR) shuo.huang@nju.edu.cn, Xie, Ran1,3 (AUTHOR) ranxie@nju.edu.cn
Publikováno v:
Angewandte Chemie. 5/15/2023, Vol. 135 Issue 21, p1-10. 10p.
Akademický článek
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