Výsledky vyhledávání - "K Shailubhai"

Immunotherapy with oral administration of humanized anti-CD3 monoclonal antibody: a novel gut-immune system-based therapy for metaflammation and NASH

Autor: K Shailubhai, A Sanyal, Yaron Ilan

Publikováno v: Clinical and experimental immunology. 193(3)

Summary The immune system plays a role in the pathogenesis of non-alcoholic steatohepatitis (NASH) underlying hepatocyte injury and fibrosis progression at all disease stages. Oral administration of anti-CD3 monoclonal antibody (mAb) has been shown i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518172097952829890b943526189b275
https://pubmed.ncbi.nlm.nih.gov/29920654

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Autor: Q K Huynh, G S Jacob, K O Broschat, H Boddupalli, H H Yu, K Shailubhai

Publikováno v: Glycoconjugate Journal. 16:357-363

A soluble sulfotransferase from porcine serum which catalyzes the transfer of sulfate from adenosine 3'-phosphate 5'-phosphosulphate (PAPS) to 2'-fucosyllactose (2'-FL) was purified 36,333-fold using a combination of conventional and affinity chromat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::325b99cb641883ea5501fefc0e5b2377
https://doi.org/10.1023/a:1007052228230

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An Enzymatic Procedure for the Preparation and Purification of 3′-Phosphoadenosine 5′-Phospho- [35S]Sulfate ([35S]PAPS): Applications in Syntheses of 8-Azido and 8-Bromo Derivatives of [35S]PAPS

Autor: K. Shailubhai, J.J. Schmuke, R.K. Singh, G.S. Jacob

Publikováno v: Analytical Biochemistry. 243:165-170

This paper describes a rapid and an efficient procedure for the enzymatic synthesis of 3′-phosphoadenosine 5′-phospho[35S]sulfate ([35S]PAPS). [35S]PAPS was synthesized by incubating ATP and a carrier-free [35S]Na235SO4with ATP sulfurylase, a rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d415e1ab1dbb430e61506d0258f92e18
https://doi.org/10.1006/abio.1996.0496

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Glucosidase I, a transmembrane endoplasmic reticular glycoprotein with a luminal catalytic domain

Autor: Inder K. Vijay, Ela S. Saxena, Gayatri M. Varma, K Shailubhai, Budhan S. Pukazhenthi

Publikováno v: Journal of Biological Chemistry. 266:16587-16593

We have analyzed the functional domain structure of rat mammary glucosidase I, an enzyme involved in N-linked glycoprotein processing, using biochemical and immunological approaches. The enzyme contains a high mannose type sugar chain that can be cle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c1cd76f32ef12cd2e60ba53ec3570c0
https://doi.org/10.1016/s0021-9258(18)55341-2

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Photoaffinity labeling of glucosyltransferase of the dolichol cycle from rat mammary gland

Autor: Inder K. Vijay, K Shailubhai, C Illeperuma, M Tayal

Publikováno v: Journal of Biological Chemistry. 265:14105-14108

UDP-Glc:dolichol phosphate glucosyltransferase from lactating rat mammary gland has been partially purified by a combination of (NH4)2SO4 fractionation, gel filtration, ion-exchange chromatography on DEAE-TSK, and affinity chromatography. The partial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::973d77158a57612edbfa0f159ae05a05
https://doi.org/10.1016/s0021-9258(18)77274-8

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Developmental regulation of glucosidase I, an enzyme involved in the processing of asparagine-linked glycoproteins in rat mammary gland

Autor: Inder K. Vijay, K Shailubhai, A K Balapure, E. S. Saxena

Publikováno v: Journal of Biological Chemistry. 265:9701-9706

Glucosidase I involved in the processing of N-linked glycoproteins was purified to homogeneity from the lactating rat mammary gland. The purified enzyme exhibited a single band at 85 kDa on 10% sodium dodecyl sulfate-polyacrylamide gel electrophoresi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c891df530633ae4357165c6a2e0c5a1
https://doi.org/10.1016/s0021-9258(19)38727-7

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Uroguanylin treatment suppresses polyp formation in the Apc(Min/+) mouse and induces apoptosis in human colon adenocarcinoma cells via cyclic GMP

Autor: K, Shailubhai, H H, Yu, K, Karunanandaa, J Y, Wang, S L, Eber, Y, Wang, N S, Joo, H D, Kim, B W, Miedema, S Z, Abbas, S S, Boddupalli, M G, Currie, L R, Forte

Publikováno v: Cancer research. 60(18)

The enteric peptides, guanylin and uroguanylin, are local regulators of intestinal secretion by activation of receptor-guanylate cyclase (R-GC) signaling molecules that produce cyclic GMP (cGMP) and stimulate the cystic fibrosis transmembrane conduct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::da58a14ed3cc8f98471234d59ced13fb
https://pubmed.ncbi.nlm.nih.gov/11016642

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Isolation and characterization from porcine serum of a soluble sulfotransferase responsible for 6-O-sulfation of the galactose residue in 2'-fucosyllactose: implications in the synthesis of the ligand for L-selectin

Autor: Q K, Huynh, K, Shailubhai, H, Boddupalli, H H, Yu, K O, Broschat, G S, Jacob

Publikováno v: Glycoconjugate journal. 16(7)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::473d7ccd1f6560f1fbbbb3d1b463610f
https://pubmed.ncbi.nlm.nih.gov/10619708

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