Zobrazeno 1 - 10
of 134
pro vyhledávání: '"K Sandeep, Prabhu"'
Autor:
Sangshan Tian, Devendra Paudel, Fuhua Hao, Rabin Neupane, Rita Castro, Andrew D. Patterson, Amit K. Tiwari, K. Sandeep Prabhu, Vishal Singh
Publikováno v:
Cancer Reports, Vol 6, Iss 11, Pp n/a-n/a (2023)
Abstract Background and Aim There is an increased risk of colon cancer associated with inflammatory bowel disease (IBD). Dietary fibers (DFs) naturally present in vegetables and whole grains offer numerous beneficial effects on intestinal health. How
Externí odkaz:
https://doaj.org/article/a3dc61766c5a4a138597cc65de5fdcaf
Autor:
K. Sandeep Prabhu
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)
Some studies suggest that the trace element selenium protects against colorectal cancer (CRC). However, the contribution of selenoprotein P (SELENOP), a unique selenocysteine-containing protein, to sporadic colorectal carcinogenesis challenges this p
Externí odkaz:
https://doaj.org/article/f1fc87ac205a447ba0e36ebf84768a7e
Autor:
Fenghua Qian, Shaneice K. Nettleford, Jiayan Zhou, Brooke E. Arner, Molly A. Hall, Arati Sharma, Charyguly Annageldiyev, Randy M. Rossi, Diwakar B. Tukaramrao, Deborpita Sarkar, Shailaja Hegde, Ujjawal H. Gandhi, Emily R. Finch, Laura Goodfield, Michael D. Quickel, David F. Claxton, Robert F. Paulson, K. Sandeep Prabhu
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112794- (2023)
Summary: Relapse of acute myeloid leukemia (AML) remains a significant concern due to persistent leukemia-initiating stem cells (LICs) that are typically not targeted by most existing therapies. Using a murine AML model, human AML cell lines, and pat
Externí odkaz:
https://doaj.org/article/ce35a814bf814b97aa20a01a202f9e01
Autor:
Sougat Misra, Tai-Jung Lee, Aswathy Sebastian, John McGuigan, Chang Liao, Imhoi Koo, Andrew D. Patterson, Randall M. Rossi, Molly A. Hall, Istvan Albert, K. Sandeep Prabhu
Publikováno v:
Redox Biology, Vol 59, Iss , Pp 102571- (2023)
Macrophages play a pivotal role in mediating inflammation and subsequent resolution of inflammation. The availability of selenium as a micronutrient and the subsequent biosynthesis of selenoproteins, containing the 21st amino acid selenocysteine (Sec
Externí odkaz:
https://doaj.org/article/d714f723979e4fb58ae6ded34917a90e
Autor:
Shaneice K. Nettleford, Chang Liao, Sarah P. Short, Randall M. Rossi, Vishal Singh, K. Sandeep Prabhu
Publikováno v:
Antioxidants, Vol 12, Iss 4, p 850 (2023)
Selenoprotein W (Selenow) is a ~9 kDa selenoprotein suggested to play a beneficial role in resolving inflammation. However, the underlying mechanisms are poorly understood. SELENOW expression in the human GI tract using ScRNAseq Gut Cell Atlas and Ge
Externí odkaz:
https://doaj.org/article/29b0493220d140d8acfdeca529b77d8d
Autor:
Rachel L. Markley, Katherine H. Restori, Bhuvana Katkere, Sarah E. Sumner, McKayla J. Nicol, Anastasia Tyryshkina, Shaneice K. Nettleford, David R. Williamson, David E. Place, Kalyan K. Dewan, Ashley E. Shay, Bradley A. Carlson, Santhosh Girirajan, K. Sandeep Prabhu, Girish S. Kirimanjeswara
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The essential micronutrient Selenium (Se) is co-translationally incorporated as selenocysteine into proteins. Selenoproteins contain one or more selenocysteines and are vital for optimum immunity. Interestingly, many pathogenic bacteria utilize Se fo
Externí odkaz:
https://doaj.org/article/99bbee9a907a441aa3a38efdca6ca9f1
Autor:
Yaxian Kong, Bei Jia, Chenchen Zhao, David F. Claxton, Arati Sharma, Charyguly Annageldiyev, Joseph S. Fotos, Hui Zeng, Robert F. Paulson, K. Sandeep Prabhu, Hong Zheng
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-11 (2019)
Abstract Background Successful treatment for acute myeloid leukemia (AML) remains challenging. Inhibiting immune checkpoint to enhance anti-tumor response is an attractive strategy for effective leukemia therapeutics. CD73 is a recently recognized im
Externí odkaz:
https://doaj.org/article/0af86c29d57640ac8a9139d616b7bb2e
Autor:
Shaneice K. Nettleford, Luming Zhao, Fenghua Qian, Morgan Herold, Brooke Arner, Dhimant Desai, Shantu Amin, Na Xiong, Vishal Singh, Bradley A. Carlson, K. Sandeep Prabhu
Publikováno v:
Frontiers in Nutrition, Vol 7 (2020)
Enteropathogenic Escherichia coli (EPEC) leads to adverse colonic inflammation associated with poor resolution of inflammation and loss of epithelial integrity. Micronutrient trace element selenium (Se) is incorporated into selenoproteins as the 21st
Externí odkaz:
https://doaj.org/article/b25d7fd4c6cf4d26814b4c5c0fcb8106
Autor:
Yuan Tian, Bipin Rimal, Jordan E. Bisanz, Wei Gui, Trenton M. Wolfe, Imhoi Koo, Iain M. Murray, Shaneice K. Nettleford, Shigetoshi Yokoyama, Fangcong Dong, K. Sandeep Prabhu, Peter J. Turnbaugh, Seth T. Walk, Gary H. Perdew, Andrew D. Patterson
Background Exposure to persistent organic pollutants (POPs) and gastrointestinal microbial disruption positively corelate with a predisposition to factors including obesity, metabolic syndrome, and type 2 diabetes; however, it is unclear if and how t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd1a5cf32e02986aaa49844601cdf641
https://doi.org/10.21203/rs.3.rs-2781053/v1
https://doi.org/10.21203/rs.3.rs-2781053/v1
Autor:
K. Sandeep Prabhu, Robert F. Paulson, Jay Whelan, Mary J. Kennett, Laura L. Goodfield, Michael D. Quickel, Avinash K. Kudva, Emily R. Finch
Current therapies for treatment of myeloid leukemia do not eliminate leukemia stem cells (LSC), leading to disease relapse. In this study, we supplemented mice with eicosapentaenoic acid (EPA, C20:5), a polyunsaturated omega-3 fatty acid, at pharmaco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d782de0ae58dca19d72c7b489efe09
https://doi.org/10.1158/1940-6207.c.6544929
https://doi.org/10.1158/1940-6207.c.6544929