Zobrazeno 1 - 10
of 16
pro vyhledávání: '"K S Spirin"'
Publikováno v:
Cornea. 17:309-314
Purpose To characterize the expression of fibrillins, microfibril components, in human corneas with pseudophakic/aphakic (PBK/ABK) bullous keratopathy. Methods Normal and PBK/ABK corneas were stained by immunofluorescence for fibrillin-1 and -2. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7429a0ae3bbb9c685863989409abbc5
https://doi.org/10.1097/00003226-199805000-00012
https://doi.org/10.1097/00003226-199805000-00012
Autor:
Adrian F. Gombart, A Tobler, M A Israel, M. Shiohara, John D Norton, H P Koeffler, K S Spirin, Akira Ishiguro
Publikováno v:
Blood. 87:5225-5231
Id proteins are helix-loop-helix (HLH) transcriptional factors that lack the basic DNA binding domain. The Id proteins have been reported generally to function as inhibitors of cell differentiation, and their gene expression is often downregulated du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4832530802d65619235314af0681233
https://doi.org/10.1182/blood.v87.12.5225.bloodjournal87125225
https://doi.org/10.1182/blood.v87.12.5225.bloodjournal87125225
Autor:
M Rigolet, Akira Ishiguro, John D. Norton, Andreas Tobler, Toshikazu Shimbo, H. P. Koeffler, M Shiohara, K S Spirin
Publikováno v:
Leukemia Research. 19:989-996
Helix-loop-helix (HLH) transcription factors are involved in cellular growth and differentiation. The Id (inhibitor of DNA binding and differentiation) HLH proteins, in a dominantly negative fashion, regulate transcriptional activities of basic HLH p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed53e8817db7191400623d9c199dbc4
https://doi.org/10.1016/0145-2126(95)00084-4
https://doi.org/10.1016/0145-2126(95)00084-4
Publikováno v:
Journal of Biological Chemistry. 270:19181-19187
WAF1 binds to cyclin-Cdk complexes and inhibits their activity, causing cell cycle arrest. Previous studies have shown that expression of WAF1 is induced through the p53-dependent pathway; WAF1 is induced in cells with functional p53 but not in cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0145bd47ce6ab0d85ba5dba59c7dce
https://doi.org/10.1074/jbc.270.32.19181
https://doi.org/10.1074/jbc.270.32.19181
Autor:
M, Saghizadeh, D J, Brown, R, Castellon, M, Chwa, G H, Huang, J Y, Ljubimova, S, Rosenberg, K S, Spirin, R B, Stolitenko, W, Adachi, S, Kinoshita, G, Murphy, L J, Windsor, M C, Kenney, A V, Ljubimov
Publikováno v:
The American journal of pathology. 158(2)
We have previously described decreased immunostaining of nidogen-1/entactin; laminin chains alpha1, alpha5, beta1,gamma1; and epithelial integrin alpha3beta1 in human diabetic retinopathy (DR) corneas. Here, using 142 human corneas, we tested whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb01d861dfb4d182ecafbe634c58cc03
https://pubmed.ncbi.nlm.nih.gov/11159210
https://pubmed.ncbi.nlm.nih.gov/11159210
Autor:
K S, Spirin, A V, Ljubimov, R, Castellon, O, Wiedoeft, M, Marano, D, Sheppard, M C, Kenney, D J, Brown
Publikováno v:
Investigative ophthalmologyvisual science. 40(13)
To validate the use of polymerase chain reaction (PCR)-amplified full-length cDNA as a substitute for mRNA in nucleic acid array and gene expression analysis.Total RNA was isolated from age-matched normal autopsy corneas and pseudophakic bullous kera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8b226fd0b85322f1f06f43ed7d920db5
https://pubmed.ncbi.nlm.nih.gov/10586931
https://pubmed.ncbi.nlm.nih.gov/10586931
Autor:
A V, Ljubimov, M, Saghizadeh, K S, Spirin, H L, Khin, S L, Lewin, L, Zardi, M A, Bourdon, M C, Kenney
Publikováno v:
Investigative ophthalmologyvisual science. 39(7)
To characterize the expression patterns of tenascin-C (TN-C) splice variants in normal corneas and in those affected by pseudophakic-aphakic bullous keratopathy (PBK-ABK).Alternatively spliced variants of TN-C mRNA from normal and age-matched human c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::704d7f8bce87e36eb66a6b47eab58106
https://pubmed.ncbi.nlm.nih.gov/9620072
https://pubmed.ncbi.nlm.nih.gov/9620072
Publikováno v:
Cornea. 17(3)
To characterize the expression of fibrillins, microfibril components, in human corneas with pseudophakic/aphakic (PBK/ABK) bullous keratopathy.Normal and PBK/ABK corneas were stained by immunofluorescence for fibrillin-1 and -2. The expression of fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b68d3bd6ba55057aba8164bf514e6430
https://pubmed.ncbi.nlm.nih.gov/9603388
https://pubmed.ncbi.nlm.nih.gov/9603388
Publikováno v:
International Journal of Oncology.
Cell cycle regulators have recently been implicated in oncogenic transformation of cells, including the cyclins active in the G1 phase of the cell cycle and their respective cyclin-dependent kinases (CDK) whose activities are regulated by a set of in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327d37a3598ec91c6d83870cb7a1c2b8
https://doi.org/10.3892/ijo.11.4.737
https://doi.org/10.3892/ijo.11.4.737
Autor:
Seisho Takeuchi, Carl W. Miller, Norihiko Kawamata, H P Koeffler, Yoshihiro Hatta, Koike M, Hiroya Asou, K S Spirin, J F Simpson, W. Verbeek
Publikováno v:
International Journal of Oncology.
Recently, a novel candidate tumor suppressor gene, DPC 4/SMAD 4, has been implicated in the development of pancreatic cancers. Its location at human chromosome 18q21 prompted us to investigate this gene in a large series of primary tumors located out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::745428c9ac31097cc476be1e38d69a2b
https://doi.org/10.3892/ijo.10.2.257
https://doi.org/10.3892/ijo.10.2.257