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Profound hypotension in a tetraplegic patient following angiotensin-converting enzyme inhibitor lisinopril. Case report

Autor: K S Koch, James K. Schmitt, Meena Midha

Publikováno v: Spinal Cord. 32:871-874

We present the case of a 60 year old C6 complete tetraplegic patient who developed profound hypotension following initiation of the angiotensin-converting enzyme inhibitor lisinopril to control blood pressure. Other causes of hypotension, such as myo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67d5a35ec2e3a2a5ca71b0b7f0ac9ef
https://doi.org/10.1038/sc.1994.133

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Proliferation of Hepatocytes

Autor: Hyam L. Leffert, K. S. Koch

Publikováno v: Ciba Foundation Symposium 55-Hepatotrophic Factors

Hepatocyte proliferation may be controlled by reversible patterns of endocrine changes, monitored by the liver, involving known hormones and their receptors. A two-programme model of related interactions among nutrients, specific lipoproteins, and hi

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https://doi.org/10.1002/9780470720363.ch4

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Application of green fluorescent protein-protein A fusion protein to western blotting

Autor: T, Aoki, K S, Koch, H L, Leffert, H, Watabe

Publikováno v: Methods in enzymology. 302

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4e2778235eb41fc96d1fa75de5cb1003
https://pubmed.ncbi.nlm.nih.gov/12876778

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Inactivation of plasmid reporter gene expression by one benzo(a)pyrene diol-epoxide DNA adduct in adult rat hepatocytes

Autor: K S, Koch, R G, Fletcher, M P, Grond, A I, Inyang, X P, Lu, D A, Brenner, H L, Leffert

Publikováno v: Cancer research. 53

Polycyclic aromatic hydrocarbons such as benzo(a)pyrene diol-epoxide (BPDE-I) cause hepatocellular carcinoma. To identify short-term carcinogen effects, we studied hepatocytes transfected with nonreplicating plasmids, adducted covalently with BPDE-I,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ef47d6ae20fd3ffa4c8d52f5080e6adc
https://pubmed.ncbi.nlm.nih.gov/8485714

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Induction of cyclin mRNA and cyclin-associated histone H1 kinase during liver regeneration

Autor: X P, Lu, K S, Koch, D J, Lew, V, Dulic, J, Pines, S I, Reed, T, Hunter, H L, Leffert

Publikováno v: The Journal of biological chemistry. 267(5)

Cyclins and cyclin-associated cdc kinases are key regulators of oocyte maturation (Maller, J. L. (1990) in The Biology and Medicine of Signal Transduction (Nishizuka, Y., Endo, M., and Tanaka, C., eds) pp. 323-328, Raven Press, New York), yeast cell

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https://pubmed.ncbi.nlm.nih.gov/1310673

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Cellular and molecular biology of hepatocyte growth, regeneration and gene expression

Autor: H L, Leffert, K S, Koch, X P, Lu, D A, Brenner, M, Karin, H F, Skelly, R A, Rippe, G, Fey, M, Chojkier

Publikováno v: Advances in second messenger and phosphoprotein research. 24

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4d32b6c2de41a089c2ed6840a1fa7ae4
https://pubmed.ncbi.nlm.nih.gov/2169815

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Mitogens and hepatocyte growth control in vivo and in vitro

Autor: K. S. Koch, X. P. Lu, D. A. Brenner, G. H. Fey, A. Martinez-Conde, H. L. Leffert

Publikováno v: In Vitro Cellular & Developmental Biology. 26:1202-1202

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::698e7349ac101d9ac6cdf288c3d863e3
https://doi.org/10.1007/bf02623700

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Hormonal control of rat liver regeneration

Autor: Hyam L. Leffert, K. S. Koch, B. Rubalcava, T. Moran

Publikováno v: Gastroenterology. 76:1470-1482

One problem of animal cell growth regulation which has generated tremendous controversy and speculation has been the search for “hepatotrophic” factors.’ Eagerly sought because of their postulated role in regulating liver regeneration-a rapid b

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https://doi.org/10.1016/0016-5085(79)90418-9

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Transforming Growth Factor-α Stimulates Proto-Oncogene c-junExpression and a Mitogenic Program in Primary Cultures of Adult Rat Hepatocytes

Autor: David A. Brenner, K. S. Koch, Hyam L. Leffert

Publikováno v: DNA. 8:279-285

Human transforming growth factor-alpha (TGF-alpha, MW 5547) initiates a mitogenic program in "quiescent" 11-to 13-day-old primary cultures of adult rat hepatocytes. Using validated growth reinitiation assays and chemically defined conditions (Koch an

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https://doi.org/10.1089/dna.1.1989.8.279

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GROWTH CONTROL OF DIFFERENTIATED FETAL RAT HEPATOCYTES IN PRIMARY MONOLAYER CULTURE

Autor: Hyam L. Leffert, K. S. Koch

Publikováno v: Journal of Cell Biology. 62:780-791

Serum-deficient ≤0.00003% vol/vol) conditioned medium (CM) obtained from primary cultures of fetal rat hepatocytes initiates DNA synthesis and mitosis in homologous quiescent cultures. CM similarly prepared from 3T3 fibroblast cultures is inactive.

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https://doi.org/10.1083/jcb.62.3.780

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