Zobrazeno 1 - 10
of 13
pro vyhledávání: '"K S, Kilgore"'
Publikováno v:
The Journal of Immunology. 155:1434-1441
Although TNF-alpha and several products of the activated complement system (e.g., C3b, iC3b, and C5a) are known to modulate endothelial cell function in vitro, relatively little is known about the potential modulatory role of the membrane attack comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0c4c2b566a185307ab0fc688964a2e0
https://doi.org/10.4049/jimmunol.155.3.1434
https://doi.org/10.4049/jimmunol.155.3.1434
Publikováno v:
The Journal of Immunology. 150:1055-1064
The purpose of this study was to determine if recombinant human soluble CR1 (sCR1) could prevent tissue damage associated with the activation of human complement. Directly mediated human complement-dependent myocardial injury was induced in the rabbi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cf5ace5715aac1a21975dca602c3693
https://doi.org/10.4049/jimmunol.150.3.1055
https://doi.org/10.4049/jimmunol.150.3.1055
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(3)
Glycosaminoglycans, including heparin, have been demonstrated both in vitro and in vivo to protect the ischemic myocardium against reperfusion injury. In the present study, we sought to determine whether the cardioprotective effects of heparin admini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b2a28d4b4518a18c535a77a491d2bdf2
https://pubmed.ncbi.nlm.nih.gov/10454476
https://pubmed.ncbi.nlm.nih.gov/10454476
Publikováno v:
Inflammation. 22(6)
A variety of inflammatory diseases are accompanied by activation of the complement system. We examined the role of the membrane attack complex (MAC) in mediating neutrophil adhesion to endothelial cells. To assemble the MAC in endothelial cell monola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e96ec3431c36f3a2b6706b5d6ea34b7
https://pubmed.ncbi.nlm.nih.gov/9824773
https://pubmed.ncbi.nlm.nih.gov/9824773
Autor:
K S, Kilgore, K L, Powers, M M, Imlay, A, Malani, D I, Allen, J T, Beyer, M B, Anderson, J S, Warren
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 286(1)
We examined the protective effects of GM2941, a sulfated glycomimetic of the complex carbohydrate sialyl Lewis(x), in a model of pulmonary granuloma development. This study was based on the rationale that formation of glucan-induced lung granulomas i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7344947afe5c60cc4f4d94b3ea3e0733
https://pubmed.ncbi.nlm.nih.gov/9655889
https://pubmed.ncbi.nlm.nih.gov/9655889
Autor:
K S, Kilgore, K B, Naylor, E J, Tanhehco, J L, Park, E A, Booth, R A, Washington, B R, Lucchesi
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 285(3)
Pentosan polysulfate (PPS) is a highly sulfated semisynthetic polysaccharide possessing a higher negative charge density and degree of sulfation than heparin. Like other glycosaminoglycans, the structural and chemical properties of PPS promote bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef39ece10bd7f5cc26ea514707e386e2
https://pubmed.ncbi.nlm.nih.gov/9618399
https://pubmed.ncbi.nlm.nih.gov/9618399
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 284(1)
One of the foremost mechanisms involved in the pathogenesis of myocardial reperfusion injury is the adhesion of neutrophils within the myocardium. The initial neutrophil-endothelial cell interactions are mediated by the selectin family of adhesion mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::02c5aaa157d7c927da46c7542311ae4f
https://pubmed.ncbi.nlm.nih.gov/9435207
https://pubmed.ncbi.nlm.nih.gov/9435207
Autor:
K S, Kilgore, E, Schmid, T P, Shanley, C M, Flory, V, Maheswari, N L, Tramontini, H, Cohen, P A, Ward, H P, Friedl, J S, Warren
Publikováno v:
The American journal of pathology. 150(6)
Activation of the complement cascade and subsequent assembly of the membrane attack complex (MAC) occur in a number of pathophysiological settings. When formed on the surface of endothelial cells in sublytic concentrations, the MAC can induce a numbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1122363f8f6995eb0d4fe377bb068fd4
https://pubmed.ncbi.nlm.nih.gov/9176395
https://pubmed.ncbi.nlm.nih.gov/9176395
Autor:
K S, Kilgore, M M, Imlay, J P, Szaflarski, F S, Silverstein, A N, Malani, V M, Evans, J S, Warren
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 76(2)
Monocyte chemoattractant protein-1 (MCP-1), which is required for full development of glucan-induced granulomas, in the rat, is expressed in the walls of blood vessels at sites of glucan embolization. Early (1 hour) vessel wall expression of MCP-1 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3cc76f4ffc72d25227f2f45be798c1fd
https://pubmed.ncbi.nlm.nih.gov/9042155
https://pubmed.ncbi.nlm.nih.gov/9042155
Publikováno v:
The American journal of pathology. 149(3)
Cell surface assembly of the membrane attack complex (MAC) of complement occurs in a variety of pathophysiological settings. Depending upon the density and size distribution of pores formed by the MAC and the functional integrity of membrane regulato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91cb06ce61caf4ee7f827445904f9515
https://pubmed.ncbi.nlm.nih.gov/8780399
https://pubmed.ncbi.nlm.nih.gov/8780399