Zobrazeno 1 - 7
of 7
pro vyhledávání: '"K S, Keefe"'
Autor:
L, Cheng, K Y, Hostetler, S, Chaidhawangul, M F, Gardner, J R, Beadle, K S, Keefe, G, Bergeron-Lynn, G M, Severson, K A, Soules, A J, Mueller, W R, Freeman
Publikováno v:
Investigative ophthalmologyvisual science. 41(6)
To evaluate the intraocular safety and antiviral treatment efficacy of the sustained lipid prodrug of ganciclovir, 1-O-hexadecylpropanediol-3-phospho-ganciclovir (HDP-P-GCV), as an intravitreal injectable drug system for viral retinitis.HDP-P-GCV was
Autor:
L, Cheng, K Y, Hostetler, M F, Gardner, C P, Avila, G, Bergeron-Lynn, K S, Keefe, J R, Beadle, C A, Wiley, W R, Freeman
Publikováno v:
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 15(4)
This study was conducted to evaluate the vitreous clarity and intraocular therapeutic index of three preparations ofthe carboxymethyl ester of 1-O-octadecyl-sn-glycerol-3-phosphonoformate (ODG-PFA-O-Me), a long acting lipid derivative of foscarnet wi
Autor:
L, Cheng, K Y, Hostetler, M F, Gardner, C P, Avila, G, Bergeron-Lynn, K S, Keefe, C A, Wiley, W R, Freeman
Publikováno v:
Investigative ophthalmologyvisual science. 40(7)
To determine intraocular toxicity and efficacy of the lipid prodrug of foscarnet, 1-O-octadecyl-sn-glycerol-3-phosphonoformate (ODG-PFA), as a long-acting, nontoxic intravitreous injectable drug delivery system for cytomegalovirus (CMV) retinitis.ODG
Publikováno v:
Ophthalmic surgery and lasers. 29(11)
We describe a case of focal cytomegalovirus iritis in a patient with acquired immunodeficiency syndrome (AIDS) who had CMV retinitis. The autopsy showed histologic evidence of focal iritis in the left eye. This iritis was characterized by infiltratio
Publikováno v:
Current eye research. 17(6)
To characterize the anterior segment effects of cidofovir, using an animal model.Cidofovir drops, at concentrations of 0.04%, 0.4% and 4%, were instilled in eyes of guinea pigs once daily for 10 days. Fellow eyes (controls) received normal saline. Th
Publikováno v:
Investigative ophthalmologyvisual science. 39(7)
Cidofovir (HPMPC) is a potent long-acting anticytomegalovirus agent. In humans, its dose-limiting intravitreal toxicity results in the lowering of intraocular pressure (IOP). The purpose of the present study was to determine the effects of HPMPC and
Publikováno v:
Ophthalmology. 104(5)
This study was performed to determine the prognostic significance of the presence of loops defined as periodic acid-Schiff-positive fibrovascular septa that completely surround lobules of tumor cells in cases of uveal melanoma.The presence of loops w