Zobrazeno 1 - 10
of 22
pro vyhledávání: '"K S, Giacoletto"'
Autor:
P A Morton, X T Fu, J A Stewart, K S Giacoletto, S L White, C E Leysath, R J Evans, J J Shieh, R W Karr
Publikováno v:
The Journal of Immunology. 156:1047-1054
CTLA-4 expressed on activated T cells binds to CD80 (B7-1) and CD86 (B7-2) molecules present on APC with high avidity and appears to deliver a negative regulatory signal to the T cell. We have investigated the kinetics of CTLA-4 binding to CD80 and C
Autor:
R. J. Evans, R.W. Karr, Thomas J. Girard, K. S. Giacoletto, John L. Trotter, Anne H. Cross, Robin F. Lin, Richard M. Keeling
Publikováno v:
Journal of Clinical Investigation. 95:2783-2789
T cell activation involves not only recognition of antigen presented by the MHC, but also nonspecific interactions termed "costimulation." The costimulatory molecules B7-1 and B7-2 are ligands on antigen-presenting cells for the CD28 and CTLA-4 recep
Publikováno v:
The Journal of Immunology. 154:137-150
The intracellular trafficking, proteolysis, and dissociation of invariant chain (li) associated with nascent class II molecules was examined in B-lymphoblastoid cells. Metabolic labeling and Percoll gradient centrifugation was used to assess the kine
Publikováno v:
The Journal of Immunology. 152:1082-1093
Although studies on fixed APCs have demonstrated that peptide can bind to cell surface class II molecules, the mechanisms by which peptide-class II complexes are formed in viable cells is largely unexplored. To explore the possibility that peptide lo
Autor:
Vivian L. Braciale, K S Giacoletto, N R Nygard, J Gorka, D W McCourt, W T Schaiff, L R Brown, C Bono, Mary Beth Graham, M Kabeer
Publikováno v:
The Journal of Experimental Medicine
The A/Japan/57 influenza hemagglutin (HA) peptide HA 128-145, when bound by human histocompatibility leukocyte antigen-DRw11 cells, is recognized by the human CD4+ T cell clone V1. A rabbit antiserum has been raised against HA 128-145 which recognize
Autor:
P A, Morton, X T, Fu, J A, Stewart, K S, Giacoletto, S L, White, C E, Leysath, R J, Evans, J J, Shieh, R W, Karr
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(3)
CTLA-4 expressed on activated T cells binds to CD80 (B7-1) and CD86 (B7-2) molecules present on APC with high avidity and appears to deliver a negative regulatory signal to the T cell. We have investigated the kinetics of CTLA-4 binding to CD80 and C
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 154(1)
The intracellular trafficking, proteolysis, and dissociation of invariant chain (li) associated with nascent class II molecules was examined in B-lymphoblastoid cells. Metabolic labeling and Percoll gradient centrifugation was used to assess the kine
Publikováno v:
Journal of Neuroimmunology
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(3)
Although studies on fixed APCs have demonstrated that peptide can bind to cell surface class II molecules, the mechanisms by which peptide-class II complexes are formed in viable cells is largely unexplored. To explore the possibility that peptide lo
Autor:
Andrea J. Sant, J Gorka, Vito Quaranta, Chris Bono, D M O'Sullivan, K S Giacoletto, Benjamin D. Schwartz
Publikováno v:
The Journal of Experimental Medicine
The human class II-associated chondroitin sulfate proteoglycan (CSPG) was analyzed biochemically and immunologically to determine a possible relationship with the human invariant chain (gamma 1) and its related components. The CSPG was purified by a