Zobrazeno 1 - 10
of 61
pro vyhledávání: '"K S, Channer"'
Publikováno v:
QJM. 99:127-133
Vasopressin is a peptide synthesized in the hypothalamus whose primary role is in fluid homeostasis. It has recently gained interest as a potential agent in the treatment of cardiorespiratory arrest. Initial human studies have shown benefits with vas
Publikováno v:
British Journal of Haematology. 111:974-979
Autor:
K. S. Channer, Richard P. Steeds
Publikováno v:
British Journal of Clinical Pharmacology. 46:335-341
The ‘acute coronary syndromes’ represent a spectrum of disease, from Q-wave myocardial infarction to unstable angina, in which the common pathogenic feature is the rupture of an atherosclerotic plaque, followed by platelet aggregation and thrombu
Autor:
Richard P. Steeds, K S Channer
Publikováno v:
QJM. 90:427-430
A positive family history is an established risk factor for ischaemic heart disease, but the size of the contribution relative to classical risks is open to debate. The literature suggests that inherited factors are important in the development of pr
Publikováno v:
European Heart Journal. 17:394-398
In this study we compared different dietary constituents and their effect on the angina threshold. We compared carbohydrate-rich, fat-rich and balanced liquid diets on effort tolerance in 14 patients of mean (range) 61 (41-73) years of age with chron
Autor:
T Downes, K S Channer
Publikováno v:
Postgraduate Medical Journal. 79:151-153
Ethics is about judgment, which is rarely black and white. This paper highlights some of the ethical dilemmas that face practising clinicians in their everyday life and restates how useful the General Medical Council guidance is to make appropriate d
Publikováno v:
British Journal of Anaesthesia. 72:267-271
We have compared changes in haemodynamic variables before and during transurethral resection of the prostate in 22 patients under general or spinal anaesthesia. In the general anaesthetic group there was a significant decrease in cardiac output (mean
Publikováno v:
Clinical endocrinology. 74(5)
There is a high prevalence of low testosterone and dyslipidaemia in men with type 2 diabetes. The androgen receptor CAG repeat polymorphism (AR CAG) affects receptor transcriptional activity (the shorter repeats the more sensitive AR) and is associat
Autor:
K. S. Channer
Publikováno v:
British Journal of Clinical Pharmacology. 32:267-273
1. Atrial fibrillation is an inefficient cardiac rhythm associated with impaired exercise tolerance, exertional dyspnoea, palpitation and a substantial risk of thromboembolism. 2. The first decision in management is to consider cardioversion which ca
Publikováno v:
Postgraduate Medical Journal. 67:659-662
Summary Twenty-eight patients with atrial fibrillation of less than 1 month's duration were given a single intravenous bolus of flecainide (2 mg/kg). Nineteen patients (68%) were successfully converted to sinus rhythm. Of the 19 patients with atrial