Zobrazeno 1 - 10
of 1 038
pro vyhledávání: '"K Reilly"'
Autor:
Shubham Khetan, Susan Kales, Romy Kursawe, Alexandria Jillette, Jacob C. Ulirsch, Steven K. Reilly, Duygu Ucar, Ryan Tewhey, Michael L. Stitzel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Identifying causal variants at GWAS loci is important to understand disease mechanisms. Here the authors use massively parallel reporter assays to identify type 2 diabetes-associated variants that alter cis-regulatory activity, narrowing in on the ca
Externí odkaz:
https://doaj.org/article/7935194eff76489e8d239c6329e3802f
Autor:
Douglas K. Reilly, Emily J. McGlame, Elke Vandewyer, Annalise N. Robidoux, Caroline S. Muirhead, Haylea T. Northcott, William Joyce, Mark J. Alkema, Robert J. Gegear, Isabel Beets, Jagan Srinivasan
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Reilly et al identify a neuropeptide-neuropeptide receptor (NP/NPR) module that is active in male but not in hermaphrodite C. elegans. Using a neuropeptide rescue paradigm, they demonstrate that receptor expression within pre-motor neurons mediates c
Externí odkaz:
https://doaj.org/article/8262872adf0d4433971f18f2c5029f4e
Autor:
John P. Ray, Carl G. de Boer, Charles P. Fulco, Caleb A. Lareau, Masahiro Kanai, Jacob C. Ulirsch, Ryan Tewhey, Leif S. Ludwig, Steven K. Reilly, Drew T. Bergman, Jesse M. Engreitz, Robbyn Issner, Hilary K. Finucane, Eric S. Lander, Aviv Regev, Nir Hacohen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
While genome-wide association studies have yielded thousands of trait-associated loci, identifying causal variants remains challenging. Here, the authors perform seven genomics assays in various cell types to prioritize genetic variants in the TNFAIP
Externí odkaz:
https://doaj.org/article/1ebe14a757924ee7b684604e682e0db0
Autor:
Christopher D. Chute, Elizabeth M. DiLoreto, Ying K. Zhang, Douglas K. Reilly, Diego Rayes, Veronica L. Coyle, Hee June Choi, Mark J. Alkema, Frank C. Schroeder, Jagan Srinivasan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Inter-organismal signaling is essential for animals to navigate and survive in their natural environment, yet is unclear how these chemical communication channels may have evolved. Here, authors show that TYRA-2, an endogenous tyramine/octopamine rec
Externí odkaz:
https://doaj.org/article/75603164ccb9427b951dcb3ec92772a5
Autor:
Thobile B. Dlamini, Brian K. Reilly, Dave I. Thompson, Deron E. Burkepile, Judith M. Botha, Anthony G. Rebelo
Publikováno v:
Koedoe: African Protected Area Conservation and Science, Vol 62, Iss 1, Pp e1-e8 (2020)
The Kruger National Park’s (KNP) long-running experimental burn plots (EBPs) have a history of research projects, which improve the understanding of fire in savanna ecosystems. Using data from KNP’s aerial censuses (2005–2016) and in situ dung
Externí odkaz:
https://doaj.org/article/6b7da6e057e74e728663a67d353b1b71
Autor:
Esperanza Mantilla-Rivas, MD, Ishwarya Mamidi, BS, Alex Rokni, BS, Ashleigh Brennan, BS, Md Sohel Rana, MBBS, MPH, Agnes Goldrich, BS, Monica Manrique, MD, Monica Shah, MD, Brian K. Reilly, MD, Gary F. Rogers, MD, JD, LLM, MBA, MPH, Albert K. Oh, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 8, Iss 5, p e2824 (2020)
Background:. Patients born with a cleft lip and palate undergo multiple surgical procedures, increasing the infants’ exposure to anesthesia and potential risk of neurocognitive delays. In addition, these numerous procedures lead to greater use of h
Externí odkaz:
https://doaj.org/article/d93deba98ac049d3bd224c08b4bb29f8
Autor:
Lennon Gregor, Austin K. Reilly, Tomer A. Dickstein, Sumaira Mazhar, Stanley Bram, David Gene Morgan, Yaroslav Losovyj, Maren Pink, Barry D. Stein, Valentina G. Matveeva, Lyudmila M. Bronstein
Publikováno v:
ACS Omega, Vol 3, Iss 11, Pp 14717-14725 (2018)
Externí odkaz:
https://doaj.org/article/1a1d7b7ab19342acb74f771e82dcd672
Autor:
Jeffrey J. Jackson, Grant M. Shibuya, Buvana Ravishankar, Lavanya Adusumilli, Delia Bradford, Dirk G. Brockstedt, Cyril Bucher, Minna Bui, Cynthia Cho, Christoph Colas, Gene Cutler, Adrian Dukes, Xinping Han, Dennis X. Hu, Scott Jacobson, Paul D. Kassner, George E. Katibah, Michelle Yoo Min Ko, Urvi Kolhatkar, Paul R. Leger, Anqi Ma, Lisa Marshall, Jack Maung, Andrew A. Ng, Akinori Okano, Deepa Pookot, Daniel Poon, Chandru Ramana, Maureen K. Reilly, Omar Robles, Jacob B. Schwarz, Anton A. Shakhmin, Hunter P. Shunatona, Raashi Sreenivasan, Parcharee Tivitmahaisoon, Mengshu Xu, Thant Zaw, David J. Wustrow, Mikhail Zibinsky
Publikováno v:
Journal of Medicinal Chemistry. 65:12895-12924
General control nonderepressible 2 (GCN2) protein kinase is a cellular stress sensor within the tumor microenvironment (TME), whose signaling cascade has been proposed to contribute to immune escape in tumors. Herein, we report the discovery of cell-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ef2aa8a880d39b628fb4a035cd9808
https://doi.org/10.1021/acs.jmedchem.2c00736
https://doi.org/10.1021/acs.jmedchem.2c00736
Autor:
Nicole Benjamin-Fink, Brian K. Reilly
Publikováno v:
Global Ecology and Conservation, Vol 12, Iss C, Pp 46-58 (2017)
Wildlife translocations have historically assisted in re-establishing species in areas of extinction and are currently employed in over 50 countries. Ironically, they may also be responsible for the extinction of pure genetic lineages via hybridizati
Externí odkaz:
https://doaj.org/article/60010a661cfc46f4a15c34bb94c8c31c
Publikováno v:
Cureus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d45808b2965cd27801191a28d09897e0
https://doi.org/10.7759/cureus.37901
https://doi.org/10.7759/cureus.37901