Detection of mutations in SF3B1, EIF1AX and GNAQ in primary orbital melanoma by candidate gene analysis

Autor: Anna M. Rose, Rong Luo, Utsav K. Radia, Helen Kalirai, Sophie Thornton, Philip J. Luthert, Channa N. Jayasena, David H. Verity, Sarah E. Coupland, Geoffrey E. Rose

Publikováno v: BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)

Abstract Background Ocular melanoma is a rare but often deadly malignancy that arises in the uvea (commonest primary site), conjunctiva or the orbit. Primary orbital melanoma (POM) is exceedingly rare, with approximately 60 cases reported to date. De

Externí odkaz: https://doaj.org/article/ad7ad059663d44e9ac74b5a5b0894764

Reduced Testicular Steroidogenesis and Increased Semen Oxidative Stress in Male Partners as Novel Markers of Recurrent Miscarriage

Autor: Utsav K Radia, Maria Osagie, Wayne Vessey, Waljit S. Dhillo, Lesley Regan, Anastasia Dimakopoulou, Monica Figueiredo, Rajendra Rai, Channa N. Jayasena, Larissa Franklin Revill

Publikováno v: Clinical Chemistry. 65:161-169

BACKGROUND Recurrent pregnancy loss, (RPL) affecting 1%–2% of couples, is defined as ≥3 consecutive pregnancy losses before 20-week' gestation. Women with RPL are routinely screened for etiological factors, but routine screening of male partners

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac1fc075b34eb571ec037d3e3871656
https://doi.org/10.1373/clinchem.2018.289348

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Animal Models of Diabetes-Related Male Hypogonadism

Autor: Metab Algefari, Utsav K Radia, Nick Oliver, Anastasia Dimakopoulou, Channa N. Jayasena, Waljit S. Dhillo, Suks Minhas

Publikováno v: Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 10 (2019)

Hypogonadism is the clinical syndrome associated with low testosterone secretion in men. Hypogonadism affects ~37–57% men with diabetes mellitus (1). Male reproduction is orchestrated by the hypothalamo-pituitary-gonadal (HPG) axis, which regulates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f6145e746fa1d5c6f5b03f5f8bd059
https://pubmed.ncbi.nlm.nih.gov/31620084

Author Correction: Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses

Autor: M Datoo, Thomas A. Rawlinson, C Brown-O’Sullivan, Hodgson Shc., C White, B Oguti, Eleanor Berrie, N Moya, S Felle, H Sanders, Adam J. Ritchie, M M Hou, J Drake, E Brunt, D Rajapaksa, S Provstgaard-Morys, G Gorini, Elizabeth Nuthall, J Burbage, C Munro, L Bates, J A Tree, E Y Jones, R Makinson, O E Muhanna, N Borthwick, Andreas C. Themistocleous, I Rudiansyah, Emary Krw., A Batten, D Jenkin, D J Smith, I Vichos, N Douglas, Susanna Dunachie, Hazel Morrison, S Marinou, P Osborne, A Szigeti, Bassam Hallis, Alexander J. Mentzer, Christina Dold, T Brenner, K Parker, E H Arbe-Barnes, G Meddaugh, S Lipworth, J Towner, N Turner, E Hamilton, C Downing, L Gracie, C J Cunningham, P Matthews, H Humphries, Y Peng, N Tran, I Satti, N Byard, Shuo Feng, Ciaran Gilbride, R E Drury, K Radia, D Bellamy, R Tarrant, E Howe, Daniel J. Phillips, L Cifuentes, X L Yao, Elizabeth R. Allen, L Allen, B Hanumunthadu, K Godwin, E Francis, K Sanders, H Parracho, R Kailath, N Baker, J McGlashan, S Rhead, F Jackson, S Tonks, A Ali, S Murphy, Larwood Jpj., L Tinh, T Wrin, A Linder, Irina Chelysheva, Catherine M. Green, Elizabeth J. Kelly, C Datta, B Khozoee, H Roberts, Miles W. Carroll, P M Folegatti, C V Arancibia-Cárcamo, Julian C. Knight, E Marlow, P C Proud, A Truby, Crocker Wem., Hannah Robinson, J Keen, E J Penn, L Loew, Elizabeth A. Clutterbuck, D Zizi, N Owino, E Boland, J McEwan, N G Marchevsky, E Morey, Brian Angus, M P Peralta Alvarez, P Mweu, A Killen, E A Lees, Amy Boyd, Watson Mee., A Tomic, M E Wand, T B King, S Jauregui, C W Larkworthy, S Salvador, I J Taylor, D Pulido, Fay L. Nugent, M Patrick-Smith, A T Worth, Merryn Voysey, S A Harris, T M Thomas, A Shea, Teresa Lambe, L Blackwell, R Halkerston, Katie J. Ewer, D O’Connor, L Kingham-Page, P Brown, R Fisher, S J Morris, B Huang, Michelle Fuskova, D O’Donnell, A Lelliott, E R Pabon, J Kinch, M Thomas, H Garlant, M N Ramasamy, Daniel B. Wright, K Mansatta, K Taylor, F Cappuccini, D Kerr, Jordan R. Barrett, E Schofield, Yrene Themistocleous, R Varughese, A Beveridge, M R English, D Pipini, Sandra Belij-Rammerstorfer, S Camara, F Ramos Lopez, N Howell, J Frater, J Aboagye, X Liu, A Noé, L Silva-Reyes, Huw Davies, F R Donnellan, Alison M. Lawrie, Andrew J. Pollard, E Bolam, C Sedik, Hill Avs., Simon Kerridge, R te Water Naude, Alexandra J. Spencer, C Petropoulos, Maria Moore, K Jeffery, C Oliveria, K Pfafferott, G Gupta, Catherine C. Smith, A M Lias, G Morshead, D DiTirro, N Mirtorabi, H Ratcliffe, M J Elmore, R Lopez Ramon, S Jackson, K Jones, Y Li, Stephen Taylor, M Madhavan, I Shaik, Yama F Mujadidi, J Alderson, I Baleanu, Matthew D. Snape, M Bittaye, P J O’Reilly, R White, K O’Brien, Breeze E. Cavell, J Muller, Kelly M. Thomas, M Cao, S Field, S Roche, R Tanner, D M Kelly, R Anslow, L King, Annina B. Schmid, P Iveson, Ian D. Poulton, R Song, C L Blundell, R Beckley, T Demissie, Jack Mellors, K J Ford, Sarah E. Silk, J Furze, D Harrison, K R Buttigieg, Amy Flaxman, J Chadwick, J A Henry, R Morgans, L McInroy, G Screaton, V Olchawski, S Liu, L Khan, R Morter, P Galian-Rubio, T C Hart, G Hodges, Abdessamad Tahiri-Alaoui, J Perring, S Hawkins, Emma Plested, S Koleva, B E Damratoski, L Walker, Lisa Stockdale, P Baker, G Mallett, Angela M. Minassian, E Stafford, M K Verheul, M Carr, D Knott, Nick J. Edwards, J Fowler, Sarah C. Gilbert, A Thompson, Hannah Sharpe, Andrew Gorringe, Marta Ulaszewska, Christine S. Rollier, C P Conlon, R Colin-Jones, C Turner, Eleanor Barnes, E Mukhopadhyay, S Bibi, E M Bijker, R Cooper, D T Skelly, N S Coombes, J L Marshall, Tao Dong, Jennifer Hill, C Di Maso, K Beadon, Alexander D. Douglas, Cho J-S., Sean C. Elias, Parvinder K. Aley, S Leung, Paul Klenerman, I Cabrera Puig, K R Bewley, E Clark, S Kelly, P Williams, J Hamlyn, Megan Baker, C F Da Silva, R Drake-Brockman

Publikováno v: Nature Medicine. 27:1113-1113

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22b817d0db14346f513b67f40ab92038
https://doi.org/10.1038/s41591-021-01372-z