Výsledky vyhledávání - "K R Bruckdorfer"

Akademický článek

Platelet lipid composition and platelet aggregation in human liver disease

Autor: J S Owen, R A Hutton, R C Day, K R Bruckdorfer, N McIntyre

Publikováno v: Journal of Lipid Research, Vol 22, Iss 3, Pp 423-430 (1981)

Abnormal plasma lipoproteins in patients with liver disease are associated with an increase in erythrocyte cholesterol concentration and a raised erythrocyte cholesterol/phospholipid molar ratio. We hypothesized that their platelets would also have a

Externí odkaz: https://doaj.org/article/9f3565f484e6412897e47bc78e346bc8

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Akademický článek

Decreased erythrocyte membrane fluidity and altered lipid composition in human liver disease.

Autor: J S Owen, K R Bruckdorfer, R C Day, N McIntyre

Publikováno v: Journal of Lipid Research, Vol 23, Iss 1, Pp 124-132 (1982)

Abnormal plasma lipoproteins in patients with liver disease are associated with characteristic changes in erythrocyte membrane lipid composition. The membranes are enriched in cholesterol and phosphatidylcholine and both the cholesterol/phospholipid

Externí odkaz: https://doaj.org/article/fd022421cf4743b483adabc757e365b4

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Akademický článek

Re-evaluation of lipogenesis from dietary glucose carbon in liver and carcass of mice.

Autor: N Baker, D B Learn, K R Bruckdorfer

Publikováno v: Journal of Lipid Research, Vol 19, Iss 7, Pp 879-893 (1978)

We have estimated rates of fatty acid synthesis from glucose carbon and from all 2-carbon units in liver and carcass of mice using [U-14C] glucose and 3H2O under four different nutritional states. The liver synthesized only a small fraction (2–9%)

Externí odkaz: https://doaj.org/article/0ef111b6aae44d74a9767749cdce1106

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Akademický článek

Binding of apoE-rich high density lipoprotein particles by saturable sites on human blood platelets inhibits agonist-induced platelet aggregation.

Autor: K Desai, K R Bruckdorfer, R A Hutton, J S Owen

Publikováno v: Journal of Lipid Research, Vol 30, Iss 6, Pp 831-840 (1989)

High density lipoproteins (HDL, d 1.063-1.21 g/ml) are reported to stimulate, to have no effect on, or to inhibit agonist-induced platelet aggregation. We have hypothesized that these conflicting reports might be explained by opposing effects of indi

Externí odkaz: https://doaj.org/article/02f6169308324054a1619fa27480a1d7

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Stimulation of progesterone production in human granulosa-lutein cells by lipoproteins: evidence for cholesterol-independent actions of high-density lipoproteins

Autor: K R Bruckdorfer, J Ragoobir, A E Michael, D R E Abayasekara

Publikováno v: Journal of Endocrinology. 173:103-111

Low-density lipoproteins (LDL) have been consistently reported to stimulate ovarian steroidogenesis, apparently by the provision of cholesterol as a steroidogenic substrate. Recent studies suggest that high-density lipoproteins (HDL) can also deliver

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a91fb90e2058ca1a6de7825fe82aca5
https://doi.org/10.1677/joe.0.1730103

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Modulation of vascular tone by low density lipoproteins: effects on L-arginine transport and nitric oxide synthesis

Autor: S Chirico, Jeremy D. Pearson, M T Jay, Giovanni E. Mann, David S. Leake, M. Jacobs, Richard C.M. Siow, K R Bruckdorfer

Publikováno v: Experimental Physiology. 82:349-360

Low density lipoprotein (LDL) plays an important role in atherogenesis. Focal accumulation within the arterial intima of excess amounts of cholesterol-rich LDL leads to the migration and recruitment of monocytes, which then differentiate into macroph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f9148ee78cd563476b2f8487dbd242
https://doi.org/10.1113/expphysiol.1997.sp004030

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Time-course studies by synchrotron X-ray solution scattering of the structure of human low-density lipoprotein during Cu2+-induced oxidation in relation to changes in lipid composition

Autor: K R Bruckdorfer, P.H.E. Groot, Stephen J. Perkins, Adam S. Nealis, D F Meyer, K. E. Suckling, C H MacPhee

Publikováno v: Biochemical Journal. 319:217-227

Low-density lipoproteins (LDLs) in plasma are constructed from a single molecule of apolipoprotein B-100 (apoB) (M(r) 512,000) in association with lipid [approximate M(r) (2-3) x 10(6)]. LDL oxidation is an important process in the development of ath

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134c4ad42e4fd9870d372550641f8604
https://doi.org/10.1042/bj3190217

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