Zobrazeno 1 - 6
of 6
pro vyhledávání: '"K R, Schibler"'
Publikováno v:
Acta Paediatrica. 91:9-16
To determine whether an imbalance of dendritic cell subsets might contribute to diminished adaptive host responses observed in newborn infants. It was hypothesized that the proportion of lymphoid dendritic cells would be greater than that of myeloid
Publikováno v:
Blood. 78:1241-1246
Very high concentrations of erythropoietin (epo), in clonogenic cultures, result in reduced production of neutrophils, and fetal progenitors are more sensitive to this effect of epo than are those of adults. However, the significance of this observat
Publikováno v:
Blood. 77:2129-2134
We assessed the effect of interleukin-9 (IL-9) on clonogenic maturation and cell-cycle status of hematopoietic progenitors of fetal (umbilical cord blood) and adult (bone marrow) origin. As a single agent IL-9 supported, in a concentration-dependent
Publikováno v:
Blood. 89(11)
Interleukin-10 (IL-10) downmodulates phagocytic immune responses and accentuates humoral responses. Human neonates exhibit broad immune deficits that parallel actions of IL-10. We postulated that IL-10 production would be diminished in neonatal blood
Autor:
K R, Schibler, Y, Li, R K, Ohls, N C, Nye, M C, Durham, W, White, K W, Liechty, T, Le, R D, Christensen
Publikováno v:
Blood. 84(11)
Hematopoietic progenitors obtained from the bone marrow of healthy adults fail to undergo clonogenic maturation in vitro if a source of hematopoietic growth factors is not included in the culture dishes. In contrast, a fraction of similarly purified
Publikováno v:
Blood. 82(8)
We postulated that defective generation of granulocyte colony-stimulating factor (G-CSF) by cells of newborn infants might underlie their deficiencies in upregulating neutrophil production and function during bacterial infection. To test this, we iso