Zobrazeno 1 - 10
of 444
pro vyhledávání: '"K R, Rajashankar"'
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22995 (2011)
The assembly of pili on the cell wall of Gram-positive bacteria requires transpeptidase enzymes called sortases. In Streptococcus agalactiae, the PI-1 pilus island of strain 2603V/R encodes two pilus-specific sortases (SrtC1 and SrtC2) and three pili
Externí odkaz:
https://doaj.org/article/5bb32936facf406895e5c0b0898d3005
Autor:
Eckhard Hofmann, K. R. Rajashankar, Albrecht Bufe, Wolfgang Weber, Sandra Werner, Christian Betzel, Kirsten Gehlhar
Publikováno v:
International Archives of Allergy and Immunology. 140:285-294
Background: Allergens induce the formation of specific immunoglobulin (Ig)E and harbor at least two IgE-binding regions (epitopes) to facilitate crosslinking of basophilic or mast-cell-bound specific IgE antibodies. Studies mapping linear epitopes ha
Publikováno v:
Cellular and Molecular Life Sciences (CMLS). 56:384-397
Snake venom oligomeric neurotoxins offer several unique examples of modulation of phospholipase A2 (PLA2) activity generated by molecular evolution. This phenomenon was found in evolutionary younger snakes and is probably common for representatives o
Autor:
F. de la Torre-Martínez, Christian Betzel, Miki Abo, Françoise André, Makoto Hattori, T. Hansson, Michel Laviolette, Philippe Moingeon, Philippe Harzic, Masaki Fujimura, Julia Horn, S. Ahlstedt, Redwan Moqbel, Conny Höflich, Marie-Noëlle Couret, Volker Wahn, Yuko Waseda, Toshiyuki Yamamoto, Thierry Batard, J. Magnusson, Henri Chabre, Fook Tim Chew, M.P. Borres, J. Ring, M.D. Ibáñez, Alexandre Hrabina, Kirsten Gehlhar, Shiho Furusho, I. Münster, Wolfgang Weber, Johsuke Hara, Claudine Ferland, K. R. Rajashankar, Bertrand Villet, Masahide Yasui, C. Traidl-Hoffmann, M. Boquete, Hans-Dieter Volk, U. Bengtsson, Yoriko Herai, Francis Davoine, Hanae Wada, L. Hulthén, A.I. Tabar, Robert Bunk, Takashi Sone, Tsukasa Uno, Eckhard Hofmann, Tadashi Yoshida, Kazuo Kasahara, Yoshitaka Oribe, Albrecht Bufe, Joo Eun Lee, Dominique Faccenda, Sandra Werner, Aki Hirano, Noriyuki Ohkura, Jamila Chakir, Kathrin Schmolke, Darryl J. Adamko, Koji Takahashi, P. Lemoine, F. Rodriguez, C.G.B. Peterson, Ilka Schulze, H. Behrendt, Shigeharu Myou, Sock Yong Goh, Xue Zhi Bi, Anna-Maria Dittrich, Claude André, J. van Odijk
Publikováno v:
International Archives of Allergy and Immunology. 140:361-363
Publikováno v:
Biopolymers. 42:373-382
An N-alpha-protected model pentapeptide containing two consecutive Delta Phe residues, Boc-Leu-Delta Phe-Delta Phe-Ala-Phe-NHMe, has been synthesized by solution methods and fully characterized. H-1-nmr studies provided evidence for the occurrence of
Autor:
Ratan Mani Jain, K. R. Rajashankar, Tapas K. Mal, Suryanarayanarao Ramakumar, Virander S. Chauhan
Publikováno v:
Angewandte Chemie International Edition in English. 35:765-768
Secondary structural motifs found in peptides are also generated in model compounds containing α, β-didehydrophenylalanine residues (ΔPhe). A short peptide containing two ΔPhe units, Boc-Val-ΔPhe-Leu-Phe-Ala-ΔPhe-Leu-OMe, was found to assume a
Publikováno v:
Biopolymers. 35:141-147
alpha,beta-Dehydro amino acid residues are known to constrain the peptide backbone to the beta-bend conformation. A pentapeptide containing only one alpha,beta-dehydrophenylalanine (delta Phe) residue has been synthesized and crystallized, and its so
Publikováno v:
Angewandte Chemie International Edition in English. 33:970-973
Neither a helical structure nor a spiral β-bend ribbon structure, but a flat β-bend ribbon is formed by the title compound. Peptides with 2,3-didehydroamino acid esters (α,β-didehydroamino acid esters) such as dehydrophenylalanine (ΔPhe) are of
Publikováno v:
ChemInform. 27
Autor:
Tej P. Singh, Dessislava Georgieva, Nicolay Genov, Markus Perbandt, Christian Betzel, Annemarie Fuchs, Narayana Kalkura, K. R. Rajashankar, Inn-Ho Tsai, Sankaran Banumathi
Publikováno v:
Acta crystallographica. Section D, Biological crystallography. 59(Pt 10)
The presynaptic viperotoxin F is the major lethal component of the venom of Vipera russelli formosensis (Taiwan viper). It is a heterodimer of two highly homologous (65% identity) but oppositely charged subunits: a basic and neurotoxic PLA(2) (RV-4)