Zobrazeno 1 - 8
of 8
pro vyhledávání: '"K R, Irvine"'
Autor:
Richard Terrill, David L. Bartlett, Michael Gnant, K. R. Irvine, L. A. Noll, Markus Puhlmann, H R Alexander
Publikováno v:
Scopus-Elsevier
Background: Several approaches to gene therapy for cancer have yielded promising results in rodent models. The translation of these results to the clinical realm has been delayed by the lack of tumor models in large animals. We investigated the patte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec65eba581007844df9ecbb3548a9b5
https://pubmed.ncbi.nlm.nih.gov/10528025
https://pubmed.ncbi.nlm.nih.gov/10528025
Autor:
K R, Irvine, M R, Parkhurst, E P, Shulman, J P, Tupesis, M, Custer, C E, Touloukian, P F, Robbins, A G, Yafal, P, Greenhalgh, R P, Sutmuller, R, Offringa, S A, Rosenberg, N P, Restifo
Publikováno v:
Cancer research. 59(11)
To study the induction of anti-"self" CD8+ T-cell reactivity against the tumor antigen gp100, we used a mouse transgenic for a chimeric HLA-A*0201/H-2 Kb molecule (A2/Kb). We immunized the mice with a recombinant vaccinia virus encoding a form of gp1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ddca7a821209667985ee7f70ee002ce8
https://pubmed.ncbi.nlm.nih.gov/10363968
https://pubmed.ncbi.nlm.nih.gov/10363968
Publikováno v:
Molecular Approaches to Tumor Immunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95a842f3ddc36f3e16b5a73dc93b25b0
https://doi.org/10.1142/9789812817259_0011
https://doi.org/10.1142/9789812817259_0011
Autor:
S, Gurunathan, K R, Irvine, C Y, Wu, J I, Cohen, E, Thomas, C, Prussin, N P, Restifo, R A, Seder
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(9)
CD40/CD40 ligand interactions have a central role in the induction of both humoral and cellular immunity. In this study, we examined whether a plasmid expressing CD40 ligand/trimer (CD40LT) could enhance immune responses in vivo. BALB/c mice were inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2c378fe2b19f2e117430eb6874951a6
https://pubmed.ncbi.nlm.nih.gov/9794383
https://pubmed.ncbi.nlm.nih.gov/9794383
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 154(9)
P815A is a naturally occurring tumor rejection Ag of the methylcholanthrene-induced murine mastocytoma P815. The gene encoding the Ag P815A, designated P1A, is identical to that encoded in the normal genome of the DBA/2 mouse. A recombinant vaccinia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4698043ec79dc23ede69592c3edd2c70
https://pubmed.ncbi.nlm.nih.gov/7722317
https://pubmed.ncbi.nlm.nih.gov/7722317
Autor:
N P, Restifo, I, Bacík, K R, Irvine, J W, Yewdell, B J, McCabe, R W, Anderson, L C, Eisenlohr, S A, Rosenberg, J R, Bennink
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 154(9)
CD8+ T lymphocytes (TCD8+) play an important role in cellular immune responses. TCD8+ recognize MHC class I molecules complexed to peptides of 8 to 10 residues derived largely from cytosolic proteins. Proteins are generally thought to be fragmented i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::375002e8ae715c766d51e91c85c6c85a
https://pubmed.ncbi.nlm.nih.gov/7722298
https://pubmed.ncbi.nlm.nih.gov/7722298
Autor:
B J, McCabe, K R, Irvine, M I, Nishimura, J C, Yang, P J, Spiess, E P, Shulman, S A, Rosenberg, N P, Restifo
Publikováno v:
Cancer research. 55(8)
Anticancer vaccine strategies can now target intracellular antigens that are involved in the process of malignant transformation, such as oncogene products or mutated tumor suppressor genes. Fragments of these antigens, generally 8-10 amino acids in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d6bf29f92e5486a1d9899092e0bf8d21
https://pubmed.ncbi.nlm.nih.gov/7536130
https://pubmed.ncbi.nlm.nih.gov/7536130
Publikováno v:
Folia biologica. 40(1-2)
Activated CD8+ T cells (TCD8+) can directly recognize malignant cells because processed fragments of tumour associated antigens (TAA), 8-10 amino acids in length and complexed with MHC class I molecules, are displayed on tumour cell surfaces. Tumour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84be433762b4dcb9bd6d509ced86629d
https://pubmed.ncbi.nlm.nih.gov/7958066
https://pubmed.ncbi.nlm.nih.gov/7958066