Zobrazeno 1 - 10
of 16
pro vyhledávání: '"K R, Hightower"'
Publikováno v:
Photochemistry and photobiology. 69(5)
A preliminary study was undertaken to establish whether low-dose UV irradiation (UVB) affects calcium cell signaling in rabbit lens epithelia. In a suspension of lens epithelial cells (line NN1003A), changes in intracellular Ca2+ were measured by Fur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c68985b9fda4fc87da38c2fe3d635b8c
https://pubmed.ncbi.nlm.nih.gov/10333767
https://pubmed.ncbi.nlm.nih.gov/10333767
Autor:
K R, Hightower, J P, McCready
Publikováno v:
Investigative ophthalmologyvisual science. 32(2)
Selenite (Se) cataract in rabbit lenses was investigated in vitro to define target sites of Se that might be involved in calcium elevation and lens opacification. Experiments in which the anterior or the posterior surface of the lens was exposed to S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6880f163e0547fe0bfa3b63360c921a1
https://pubmed.ncbi.nlm.nih.gov/1825204
https://pubmed.ncbi.nlm.nih.gov/1825204
Autor:
K R, Hightower
Publikováno v:
Investigative ophthalmologyvisual science. 24(10)
Biosynthesis of lens proteins, as assessed by the incorporation of 14C-histidine, was investigated in young rabbit lenses cultured under conditions designed to specifically elevate lens calcium. While such lenses rarely were obtained without small de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::51702077c218558de39aaabf149106da
https://pubmed.ncbi.nlm.nih.gov/6618804
https://pubmed.ncbi.nlm.nih.gov/6618804
Autor:
K R, Hightower, S E, Harrison
Publikováno v:
Investigative ophthalmologyvisual science. 28(8)
Results were obtained which demonstrate that calcium accumulation in the rabbit lens may suppress glycolysis, not only by its inhibitory effect on cation transport but by its direct effect on glycolytic enzymes. In lenses cultured in calcium-enriched
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66c5cd8df9f4224752d561a8b8436085
https://pubmed.ncbi.nlm.nih.gov/3610559
https://pubmed.ncbi.nlm.nih.gov/3610559
Publikováno v:
Investigative ophthalmologyvisual science. 24(9)
The present study was designed to examine the possible role of calcium in the opacification of x-ray-induced cataract in rabbit. The results demonstrate that the concentration of calcium in x-rayed lenses, just prior to lens hydration (7.5 weeks post
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d6007ef5238095c2013a9a4c192e23b
https://pubmed.ncbi.nlm.nih.gov/6224754
https://pubmed.ncbi.nlm.nih.gov/6224754
Autor:
K R, Hightower, J P, McCready
Publikováno v:
Investigative ophthalmologyvisual science. 30(1)
Selenium toxicity was investigated in cultured rabbit lenses to provide further information about the role of Ca++ in Se cataract. At a dose of 0.1 mM for 20 hr, Se induces a 10% change in Na levels within 6 hr, a 30% increase after 20 hr, and a thre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::23f996f4718f0ba91b811d6cdd8ceb56
https://pubmed.ncbi.nlm.nih.gov/2912910
https://pubmed.ncbi.nlm.nih.gov/2912910
Publikováno v:
Investigative ophthalmologyvisual science. 26(7)
Calcium-sensitive microelectrodes have been employed to determine that the free, intracellular concentration of calcium in the lens is approximately 30 microM. Additionally, active extrusion of intracellular calcium has been demonstrated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::51e9819b6c592205c4645ca68efe2986
https://pubmed.ncbi.nlm.nih.gov/2409051
https://pubmed.ncbi.nlm.nih.gov/2409051
Publikováno v:
Investigative ophthalmologyvisual science. 28(10)
The purpose of this experiment was to assess the roles of free, intracellular calcium and calcium-dependent neutral protease (calpain II, EC.34.22.17) in selenite nuclear cataract. Free calcium ion concentrations within lens nuclear fibers during sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84f6626e0f451284389f266460128c73
https://pubmed.ncbi.nlm.nih.gov/2820891
https://pubmed.ncbi.nlm.nih.gov/2820891
Publikováno v:
Investigative ophthalmologyvisual science. 30(8)
Parallel studies of the ionic balance and membrane permeability characteristics of normal human lenses were carried out in three countries (USA, England and Italy). Similar age-related changes were found in each laboratory. The lens membrane potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4012f73c1eaa73310bdd13f446a93679
https://pubmed.ncbi.nlm.nih.gov/2759800
https://pubmed.ncbi.nlm.nih.gov/2759800
Publikováno v:
Investigative ophthalmologyvisual science. 19(9)
Evidence based on the following three observations suggests the existence of a calcium transport system in the mammalian lens: calcium levels in the lens are lower than that measured in the aqueous humor; calcium efflux is temperature-dependent and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c778cac09f92f3e4d84830ce20fd0420
https://pubmed.ncbi.nlm.nih.gov/6447674
https://pubmed.ncbi.nlm.nih.gov/6447674