Zobrazeno 1 - 10
of 19
pro vyhledávání: '"K R, Courtney"'
Publikováno v:
Molecular pharmacology. 42(3)
Voltage-clamp studies of myelinated nerve fibers that are designed to determine structural criteria regarding selective drug blocking of open and inactive states of the sodium channel are described. A series of phenothiazines were studied. It was sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c2179dccdced3bb0d38756de90cb39f
https://pubmed.ncbi.nlm.nih.gov/1328843
https://pubmed.ncbi.nlm.nih.gov/1328843
Publikováno v:
Proceedings of the Western Pharmacology Society. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a14ac7a80bc62f7bd7ffd6f078d0783d
https://pubmed.ncbi.nlm.nih.gov/1502219
https://pubmed.ncbi.nlm.nih.gov/1502219
Autor:
K R, Courtney
Publikováno v:
Proceedings of the Western Pharmacology Society. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e761c0c0fe7ffb091dfafb2a509139ed
https://pubmed.ncbi.nlm.nih.gov/1502218
https://pubmed.ncbi.nlm.nih.gov/1502218
Autor:
K R, Courtney
Publikováno v:
Molecular pharmacology. 37(6)
The influence that drug size has on the rate of recovery of sodium channels in heart tissue has been reexamined. A drug dimension that looks at the end-on view of the molecule provides a substantially better explanation for the size dependence of rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3acd7273dd247695352ac53b0096f6ca
https://pubmed.ncbi.nlm.nih.gov/1972773
https://pubmed.ncbi.nlm.nih.gov/1972773
Autor:
K R, Courtney, B C, Hill
Publikováno v:
Proceedings of the Western Pharmacology Society. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b8c94ea30e754b76c195ffb13a136801
https://pubmed.ncbi.nlm.nih.gov/2177191
https://pubmed.ncbi.nlm.nih.gov/2177191
Autor:
K. R. Courtney
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 255:H1554-H1557
Lidocaine blocks sodium channels during depolarizations. The rate of recovery (repriming) of drug-blocked channels between depolarizations is slowed by both membrane depolarization and by acidification. This modulation of recovery kinetics was studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d9292c10bdab36dfbad9d983a4514a
https://doi.org/10.1152/ajpheart.1988.255.6.h1554
https://doi.org/10.1152/ajpheart.1988.255.6.h1554
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 207(2)
Voltage clamp experiments were carried out on Rana catesbiana nodes of Ranvier in order to test predictions regarding the relationship between local anesthetic lipid solubility and the rate of development of and recovery from frequency-dependent incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cb98678f43bbd8154cdf6cf5a9a62018
https://pubmed.ncbi.nlm.nih.gov/712641
https://pubmed.ncbi.nlm.nih.gov/712641
Publikováno v:
Anesthesiology. 48(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ced546de6661cd1bdb01be20b9572106
https://pubmed.ncbi.nlm.nih.gov/306789
https://pubmed.ncbi.nlm.nih.gov/306789
Autor:
K R, Courtney
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 213(1)
Different local anesthetic drug structures differ significantly in their capabilities for producing frequency (f)-dependent sodium channel block. Voltage-clamped frog myelinated nerve preparations have been utilized in order to investigate structure-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b5339e812b09725b5cc5de22cb1aa87
https://pubmed.ncbi.nlm.nih.gov/6965720
https://pubmed.ncbi.nlm.nih.gov/6965720
Autor:
K R, Courtney
Publikováno v:
Proceedings of the Western Pharmacology Society. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12f66c8cde699f9035eeb1328278cbf8
https://pubmed.ncbi.nlm.nih.gov/7403128
https://pubmed.ncbi.nlm.nih.gov/7403128