Zobrazeno 1 - 3
of 3
pro vyhledávání: '"K R, Bley"'
Publikováno v:
British journal of pharmacology. 149(1)
The current study examined the utility of the recently described prostacyclin (prostanoid IP) receptor antagonist RO1138452 (2-(4-(4-isopropoxybenzyl)-phenylamino) imidazoline) as a tool for classifying prostanoid receptors.pA(2) values were determin
Publikováno v:
British journal of pharmacology. 124(3)
1. Prostanoid receptor-mediated sensitization, or excitation, of sensory nerve fibres contributes to the generation of hyperalgesia. To characterize the prostanoid receptors present on sensory neurones, biochemical assays were performed on primary cu
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 272(3)
Epibatidine has been reported to be a potent, nonopioid analgesic. In this study we further characterized its receptor interactions and its analgesic properties. Radioligand binding assays demonstrated that epibatidine has high affinity for nicotinic