Zobrazeno 1 - 10
of 1 464
pro vyhledávání: '"K Pritchard"'
Autor:
J A Hol, M I Lopez-Yurda, H Van Tinteren, M Van Grotel, J Godzinski, G Vujanic, F Oldenburger, B De Camargo, G L Ramírez-Villar, C Bergeron, K Pritchard-Jones, N Graf, M M Van den Heuvel-Eibrink
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221373 (2019)
BackgroundTo enhance risk stratification for Wilms tumour (WT) in a pre-operative chemotherapy setting, we explored the prognostic significance and optimal age cutoffs in patients treated according to International Society of Paediatric Oncology Rena
Externí odkaz:
https://doaj.org/article/832b66d90e5e48309fa7573090bd810d
Autor:
Hanna M. Ollila, Eilon Sharon, Ling Lin, Nasa Sinnott-Armstrong, Aditya Ambati, Selina M. Yogeshwar, Ryan P. Hillary, Otto Jolanki, Juliette Faraco, Mali Einen, Guo Luo, Jing Zhang, Fang Han, Han Yan, Xiao Song Dong, Jing Li, Jun Zhang, Seung-Chul Hong, Tae Won Kim, Yves Dauvilliers, Lucie Barateau, Gert Jan Lammers, Rolf Fronczek, Geert Mayer, Joan Santamaria, Isabelle Arnulf, Stine Knudsen-Heier, May Kristin Lyamouri Bredahl, Per Medbøe Thorsby, Giuseppe Plazzi, Fabio Pizza, Monica Moresco, Catherine Crowe, Stephen K. Van den Eeden, Michel Lecendreux, Patrice Bourgin, Takashi Kanbayashi, Francisco J. Martínez-Orozco, Rosa Peraita-Adrados, Antonio Benetó, Jacques Montplaisir, Alex Desautels, Yu-Shu Huang, FinnGen, Poul Jennum, Sona Nevsimalova, David Kemlink, Alex Iranzo, Sebastiaan Overeem, Aleksandra Wierzbicka, Peter Geisler, Karel Sonka, Makoto Honda, Birgit Högl, Ambra Stefani, Fernando Morgadinho Coelho, Vilma Mantovani, Eva Feketeova, Mia Wadelius, Niclas Eriksson, Hans Smedje, Pär Hallberg, Per Egil Hesla, David Rye, Zerrin Pelin, Luigi Ferini-Strambi, Claudio L. Bassetti, Johannes Mathis, Ramin Khatami, Adi Aran, Sheela Nampoothiri, Tomas Olsson, Ingrid Kockum, Markku Partinen, Markus Perola, Birgitte R. Kornum, Sina Rueger, Juliane Winkelmann, Taku Miyagawa, Hiromi Toyoda, Seik-Soon Khor, Mihoko Shimada, Katsushi Tokunaga, Manuel Rivas, Jonathan K. Pritchard, Neil Risch, Zoltan Kutalik, Ruth O’Hara, Joachim Hallmayer, Chun Jimmie Ye, Emmanuel J. Mignot
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Narcolepsy type 1 (NT1) is caused by a loss of hypocretin/orexin transmission. Risk factors include pandemic 2009 H1N1 influenza A infection and immunization with Pandemrix®. Here, we dissect disease mechanisms and interactions with environ
Externí odkaz:
https://doaj.org/article/5ce5735744474cff8886bce42fe536b9
Autor:
Margaret L Antonio, Clemens L Weiß, Ziyue Gao, Susanna Sawyer, Victoria Oberreiter, Hannah M Moots, Jeffrey P Spence, Olivia Cheronet, Brina Zagorc, Elisa Praxmarer, Kadir Toykan Özdoğan, Lea Demetz, Pere Gelabert, Daniel Fernandes, Michaela Lucci, Timka Alihodžić, Selma Amrani, Pavel Avetisyan, Christèle Baillif-Ducros, Željka Bedić, Audrey Bertrand, Maja Bilić, Luca Bondioli, Paulina Borówka, Emmanuel Botte, Josip Burmaz, Domagoj Bužanić, Francesca Candilio, Mirna Cvetko, Daniela De Angelis, Ivan Drnić, Kristián Elschek, Mounir Fantar, Andrej Gaspari, Gabriella Gasperetti, Francesco Genchi, Snežana Golubović, Zuzana Hukeľová, Rimantas Jankauskas, Kristina Jelinčić Vučković, Gordana Jeremić, Iva Kaić, Kevin Kazek, Hamazasp Khachatryan, Anahit Khudaverdyan, Sylvia Kirchengast, Miomir Korać, Valérie Kozlowski, Mária Krošláková, Dora Kušan Špalj, Francesco La Pastina, Marie Laguardia, Sandra Legrand, Tino Leleković, Tamara Leskovar, Wiesław Lorkiewicz, Dženi Los, Ana Maria Silva, Rene Masaryk, Vinka Matijević, Yahia Mehdi Seddik Cherifi, Nicolas Meyer, Ilija Mikić, Nataša Miladinović-Radmilović, Branka Milošević Zakić, Lina Nacouzi, Magdalena Natuniewicz-Sekuła, Alessia Nava, Christine Neugebauer-Maresch, Jan Nováček, Anna Osterholtz, Julianne Paige, Lujana Paraman, Dominique Pieri, Karol Pieta, Stefan Pop-Lazić, Matej Ruttkay, Mirjana Sanader, Arkadiusz Sołtysiak, Alessandra Sperduti, Tijana Stankovic Pesterac, Maria Teschler-Nicola, Iwona Teul, Domagoj Tončinić, Julien Trapp, Dragana Vulović, Tomasz Waliszewski, Diethard Walter, Miloš Živanović, Mohamed el Mostefa Filah, Morana Čaušević-Bully, Mario Šlaus, Dušan Borić, Mario Novak, Alfredo Coppa, Ron Pinhasi, Jonathan K Pritchard
Publikováno v:
eLife, Vol 13 (2024)
Ancient DNA research in the past decade has revealed that European population structure changed dramatically in the prehistoric period (14,000–3000 years before present, YBP), reflecting the widespread introduction of Neolithic farmer and Bronze Ag
Externí odkaz:
https://doaj.org/article/6ced7b983ff645a087276733ba254719
Autor:
Taibo Li, Nicole Ferraro, Benjamin J. Strober, Francois Aguet, Silva Kasela, Marios Arvanitis, Bohan Ni, Laurens Wiel, Elliot Hershberg, Kristin Ardlie, Dan E. Arking, Rebecca L. Beer, Jennifer Brody, Thomas W. Blackwell, Clary Clish, Stacey Gabriel, Robert Gerszten, Xiuqing Guo, Namrata Gupta, W. Craig Johnson, Tuuli Lappalainen, Henry J. Lin, Yongmei Liu, Deborah A. Nickerson, George Papanicolaou, Jonathan K. Pritchard, Pankaj Qasba, Ali Shojaie, Josh Smith, Nona Sotoodehnia, Kent D. Taylor, Russell P. Tracy, David Van Den Berg, Matthew T. Wheeler, Stephen S. Rich, Jerome I. Rotter, Alexis Battle, Stephen B. Montgomery
Publikováno v:
Cell Genomics, Vol 3, Iss 10, Pp 100401- (2023)
Summary: Each human genome has tens of thousands of rare genetic variants; however, identifying impactful rare variants remains a major challenge. We demonstrate how use of personal multi-omics can enable identification of impactful rare variants by
Externí odkaz:
https://doaj.org/article/d2548cee9ef64b4fa282cb83949a4d84
Autor:
Adele Francis Xu, Rut Molinuevo, Elisa Fazzari, Harrison Tom, Zijian Zhang, Julien Menendez, Kerriann M Casey, Davide Ruggero, Lindsay Hinck, Jonathan K Pritchard, Maria Barna
Publikováno v:
eLife, Vol 12 (2023)
The formation of paralogs through gene duplication is a core evolutionary process. For paralogs that encode components of protein complexes such as the ribosome, a central question is whether they encode functionally distinct proteins or whether they
Externí odkaz:
https://doaj.org/article/f19b23963865426f832c929b214ae367
Autor:
Courtney J Smith, Nasa Sinnott-Armstrong, Anna Cichońska, Heli Julkunen, Eric B Fauman, Peter Würtz, Jonathan K Pritchard
Publikováno v:
eLife, Vol 11 (2022)
Pleiotropy and genetic correlation are widespread features in genome-wide association studies (GWAS), but they are often difficult to interpret at the molecular level. Here, we perform GWAS of 16 metabolites clustered at the intersection of amino aci
Externí odkaz:
https://doaj.org/article/93c24e8d6a9e4e24a0498f5ad88bc407
Publikováno v:
Behavior Analysis: Research and Practice. 23:143-149
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0122b70981d19895ba6360003f0a96d1
https://doi.org/10.1037/bar0000267
https://doi.org/10.1037/bar0000267
Publikováno v:
eLife, Vol 10 (2021)
Genome-wide association studies (GWAS) have been used to study the genetic basis of a wide variety of complex diseases and other traits. We describe UK Biobank GWAS results for three molecular traits—urate, IGF-1, and testosterone—with better-und
Externí odkaz:
https://doaj.org/article/43eeb998aead48d6bd888afbfdef1476
Publikováno v:
Molecular Systems Biology, Vol 14, Iss 12, Pp 1-16 (2018)
Abstract Powerful new technologies for perturbing genetic elements have recently expanded the study of genetic interactions in model systems ranging from yeast to human cell lines. However, technical artifacts can confound signal across genetic scree
Externí odkaz:
https://doaj.org/article/81888eb70d3649e9ae36b228858ed3bb
Autor:
James E. Voss, Raiees Andrabi, Laura E. McCoy, Natalia de Val, Roberta P. Fuller, Terrence Messmer, Ching-Yao Su, Devin Sok, Salar N. Khan, Fernando Garces, Laura K. Pritchard, Richard T. Wyatt, Andrew B. Ward, Max Crispin, Ian A. Wilson, Dennis R. Burton
Publikováno v:
Cell Reports, Vol 21, Iss 1, Pp 222-235 (2017)
Recent efforts toward HIV vaccine development include the design of immunogens that can engage B cell receptors with the potential to affinity mature into broadly neutralizing antibodies (bnAbs). V2-apex bnAbs, which bind a protein-glycan region on H
Externí odkaz:
https://doaj.org/article/8111a18ec8c54af6bd246490f600391f