Zobrazeno 1 - 10
of 112
pro vyhledávání: '"K Peppel"'
Publikováno v:
The Journal of Immunology. 151:5699-5703
We previously reported that a chimeric protein consisting of the human p55 TNF receptor covalently linked to a murine IgG1 Fc heavy chain acts as an efficient TNF inhibitor, as a result of its high binding affinity for native TNF trimers of both muri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b34a277e97f63b5cb89404b8893c84d2
https://doi.org/10.4049/jimmunol.151.10.5699
https://doi.org/10.4049/jimmunol.151.10.5699
Publikováno v:
The Journal of Experimental Medicine
Using a multistep polymerase chain reaction method, we have produced a construct in which a cDNA sequence encoding the extracellular domain of the human 55-kD tumor necrosis factor (TNF) receptor is attached to a sequence encoding the Fc portion and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae50ae697f6098ab5618ac40c5e0ba5
https://doi.org/10.1084/jem.174.6.1483
https://doi.org/10.1084/jem.174.6.1483
Autor:
K Peppel, Corrado Baglioni
Publikováno v:
Journal of Biological Chemistry. 266:6663-6666
The pathway of degradation of human interferon-beta (IFN-beta) mRNA was examined in murine C127 cells that carry an expression vector for this mRNA. The IFN-beta mRNA decayed with a half-life of approximately 45 min in actinomycin D-treated cells and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00740a2a4591c0af86e3f9821027699f
https://doi.org/10.1016/s0021-9258(20)89546-5
https://doi.org/10.1016/s0021-9258(20)89546-5
Publikováno v:
The Journal of Experimental Medicine
Different vectors were constructed that expressed the human interferon-beta (IFN-beta) mRNA constitutively and contained various deletions in the 3' untranslated region (UTR). AU-rich sequences in the 3' UTR were specifically deleted in two vectors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba571c4ab1977e21ed1da3a0895a0145
https://doi.org/10.1084/jem.173.2.349
https://doi.org/10.1084/jem.173.2.349
Publikováno v:
Investigative ophthalmologyvisual science. 42(8)
Drainage of aqueous humor from the human eye appears dependent on intracellular volume of trabecular meshwork (TM) cells, the predominant cell type of the human outflow pathway. Thus, the modulation of water and solute flux across the plasma membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6416303ecccca4f8662aa44283b9cc8e
https://pubmed.ncbi.nlm.nih.gov/11431445
https://pubmed.ncbi.nlm.nih.gov/11431445
Akademický článek
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Publikováno v:
Journal of immunological methods. 169(1)
We have exploited the extremely high binding specificity of the 55 kDa human tumor necrosis factor (TNF) receptor in an assay designed to detect TNF with sensitivity limited only by limits in the detection of 131 I. Bivalent derivatives of the 55 kDa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a905503d268cac1f3f53fa3756a44b
https://pubmed.ncbi.nlm.nih.gov/8133076
https://pubmed.ncbi.nlm.nih.gov/8133076
Publikováno v:
European cytokine network. 3(6)
Tumor necrosis factor (TNF) is a protein hormone which mediates diverse inflammatory conditions, but which also may be involved in physiologic processes. To detect the expression of TNF as it might occur in normal tissues we developed a transgenic mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47e7a00c29c94018160d82b04c6fdb16
https://pubmed.ncbi.nlm.nih.gov/1296801
https://pubmed.ncbi.nlm.nih.gov/1296801
Autor:
K, Peppel, C, Baglioni
Publikováno v:
BioTechniques. 9(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f69333ee331dcae9b8d4118669ceec44
https://pubmed.ncbi.nlm.nih.gov/1702975
https://pubmed.ncbi.nlm.nih.gov/1702975
Akademický článek
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