Zobrazeno 1 - 10
of 59
pro vyhledávání: '"K P, Hoyes"'
Autor:
Ian D. Morris, K. P. Hoyes
Publikováno v:
International Journal of Andrology. 19:199-204
Publikováno v:
Journal of experimentalclinical cancer research : CR. 20(4)
Clinical trials with autologous indium-114m-labelled lymphocytes have revealed significant anti-tumour effects in chronic lymphocytic leukaemia patients with highly resistant disease. Substitution of the lymphocyte vector with heat-damaged red blood
Autor:
B I, Lord, K P, Hoyes
Publikováno v:
Radiation research. 152
Preconception paternal irradiation has been implicated in a localized excess of childhood leukemia and non-Hodgkin's lymphoma close to a nuclear reprocessing plant. Other epidemiological studies, however, threw doubt on the validity of this hypothesi
Publikováno v:
Cancer research. 58(24)
An unusual clinical finding in ataxia-telangiectasia, a human disorder caused by mutations in atm, is exquisite sensitivity to gamma irradiation. By contrast, homozygous deletion of p53 is marked by radiation resistance in certain tissue compartments
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 39(5)
Localization of Auger-emitting radionuclides within spermatozoa could lead to the induction of transmissible genetic damage. We have quantified in vitro uptake of the widely used diagnostic Auger-emitters, (111)In and 99mTc, by ejaculated human sperm
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 37(2)
In an attempt to explain the deleterious effects of gonadal radionuclide localization, we examined the role of transferrin in testicular radionuclide uptake.In vivo testicular uptake and retention of the transferrin binding radionuclides 114mIn-citra
Publikováno v:
Nuclear Medicine Communications. 24:448-449
Publikováno v:
Radiation research. 139(2)
The cytotoxic and mutagenic consequences of systemic administration of 114mIn have been examined. Adult male rats were dosed intraperitoneally with 14.8 or 3.7 MBq/kg 114mIn. Approximately 0.25% of the injected radioactivity was localized within the
Publikováno v:
Radiation research. 138(1)
The effect of systemic administration of the radionuclide 114mIn on O6-alkylguanine-DNA-alkyltransferase (ATase) activity has been examined in rats. In response to 14.8 MBq/kg 114mIn injected intraperitoneally, hepatic ATase was induced maximally app
Publikováno v:
Advances in experimental medicine and biology. 356