Zobrazeno 1 - 10
of 19
pro vyhledávání: '"K P, Flora"'
Publikováno v:
Drug Development and Industrial Pharmacy. 22:475-494
Due to the high mortality rate, the therapy of cancer has been and still is under vigorous investigation. Traditional approaches to new drug development have led to the discovery of several chemotherapeutic agents, which are now routinely used in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb81acdac4a18f4499754247287d85c9
https://doi.org/10.3109/03639049609108353
https://doi.org/10.3109/03639049609108353
Autor:
K. P. Flora, Anthony E. Pegg, Henry S. Friedman, B. R. Vishnuvajjala, Dolan Me, Michael R. Grever, Robert C. Moschel
Publikováno v:
Cancer Chemotherapy and Pharmacology. 35:121-126
O6-Benzylguanine effectively inactivates the DNA-repair protein O6-alkylguanine-DNA alkyltransferase in tumor cells and has been shown to increase the cytotoxicity of chloroethylnitrosoureas. This study was undertaken to ascertain the optimal vehicle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6333bf50c5ff59401ca6758d46cf23a8
https://doi.org/10.1007/bf00686633
https://doi.org/10.1007/bf00686633
Autor:
Seiji Kageyama, Hideya Hayashi, K P Flora, B L Hoesterey, Barry D. Anderson, Hiroaki Mitsuya, Yoshiaki Kiso
Publikováno v:
Antimicrobial agents and chemotherapy. 38(5)
KNI-272 represents a peptide-based protease inhibitor having potent antiretroviral activity against human immunodeficiency virus (HIV) in vitro. The structure contains allophenylnorstatine [(2S,3S)-3-amino-2-hydroxy-4-phenylbutyric acid] with a hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e70dd4621339e109beb08ebfebe4c6aa
https://pubmed.ncbi.nlm.nih.gov/8067746
https://pubmed.ncbi.nlm.nih.gov/8067746
Publikováno v:
Journal of the National Cancer Institute. Monographs. (15)
Taxol, a unique diterpene anticancer compound derived from the bark of the Taxus brevifolia (Pacific yew) tree, induces cytotoxicity by a novel mechanism of action. An antimicrotubule agent, Taxol promotes the formation and stabilization of the tubul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ded408f16ae21a749910fd8ccd723e5
https://pubmed.ncbi.nlm.nih.gov/7912520
https://pubmed.ncbi.nlm.nih.gov/7912520
Autor:
M L, Kleinberg, M E, Duafala, C, Nacov, K P, Flora, J, Hines, K, Davis, A, McDaniel, D, Scott
Publikováno v:
American journal of hospital pharmacy. 47(2)
The stability of heroin hydrochloride in various drug-administration devices was studied. Heroin hydrochloride was supplied as the bulk powder by the National Institute on Drug Abuse and in the formulated dosage form by Evans Medical, Ltd. Stability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf27b992ab088369b415a14b97c2e6b6
https://pubmed.ncbi.nlm.nih.gov/2309730
https://pubmed.ncbi.nlm.nih.gov/2309730
Autor:
M E, Duafala, M L, Kleinberg, C, Nacov, K P, Flora, J, Hines, K, Davis, A, McDaniel, D, Scott
Publikováno v:
American journal of hospital pharmacy. 47(1)
The stability of morphine sulfate in one brand of polyvinyl chloride (PVC) container, one brand of glass syringe, and two brands of disposable infusion devices was determined. Solutions of morphine sulfate 2 and 15 mg/mL were used to fill the PVC con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b05b01b8644e18bb35a99559eb14e02
https://pubmed.ncbi.nlm.nih.gov/2301422
https://pubmed.ncbi.nlm.nih.gov/2301422
Publikováno v:
American Journal of Health-System Pharmacy. 41:1156-1159
The stability of azacitidine in four infusion fluids was studied. Azacitidine was reconstituted and diluted to final concentrations of 0.2 mg/ml and 2.0 mg/ml in glass bottles and plastic i.v. bags containing 0.9% sodium chloride injection, 5% dextro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d6c1018bc955dc064176f39a890ecb4
https://doi.org/10.1093/ajhp/41.6.1156
https://doi.org/10.1093/ajhp/41.6.1156
Autor:
G, Ahluwalia, D A, Cooney, H, Mitsuya, A, Fridland, K P, Flora, Z, Hao, M, Dalal, S, Broder, D G, Johns
Publikováno v:
Biochemical Pharmacology. 36:3797-3800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639b4a41d69feae1dc10c64367f3ed0b
https://doi.org/10.1016/0006-2952(87)90440-0
https://doi.org/10.1016/0006-2952(87)90440-0
Publikováno v:
American Journal of Health-System Pharmacy. 44:124-130
The stability of cisplatin, iproplatin, carboplatin, and tetraplatin in common intravenous solutions was studied. Admixtures of each drug in each of the following vehicles were prepared in glass containers: 0.9% sodium chloride injection, 5% dextrose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81ec4c3c8fe7dcd363429dae5a48ab06
https://doi.org/10.1093/ajhp/44.1.124
https://doi.org/10.1093/ajhp/44.1.124
Publikováno v:
American journal of hospital pharmacy. 46(10)
The stability of pibenzimol hydrochloride was evaluated after reconstitution, after addition to several intravenous fluids, and after filtration. Vials containing pibenzimol hydrochloride 50 mg were reconstituted with 2.5 mL of 0.9% sodium chloride i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b80359b9602184ac24c3b3bf89981144
https://pubmed.ncbi.nlm.nih.gov/2479268
https://pubmed.ncbi.nlm.nih.gov/2479268