Zobrazeno 1 - 10
of 10
pro vyhledávání: '"K P, Crookston"'
Autor:
Morris A. Blajchman, Alexander P. Reiner, Laurence Cooper, R. A. Sacher, K. P. Crookston, Nancy M. Heddle
Publikováno v:
Transfusion. 40:801-812
A full-term 3.5-kg newborn of Northern European descent developed massive intravascular hemolysis after RBC and FFP transfusion during an emergency laparotomy for NEC. DATs were negative before and after transfusion. The patient’s RBCs did not exhi
Publikováno v:
Blood Coagulation & Fibrinolysis. 11:79-88
To better understand the regulation of tissue plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1) during liver transplantation, we used a computer model of the human circulatory system to simultaneously evaluate the effect of t
Publikováno v:
Biochemical Journal. 312:579-586
Human alpha 2-macroglobulin (alpha 2M) is a proteinase inhibitor and carrier of certain growth factors, including transforming growth factor beta 1 (TGF-beta 1). The constitutively synthesized homologue of human alpha 2M in the adult rat is alpha 1M.
Publikováno v:
Journal of Biological Chemistry. 269:30402-30406
Transforming growth factor beta 2 (TGF-beta 2) is less potent than TGF-beta 1 in some endothelial cell proliferation assays due to the greater tendency of TGF-beta 2 to bind alpha 2-macroglobulin (alpha 2M). Substitution of TGF-beta 1 residues 40-47
Autor:
Donna J. Webb, Beni B. Wolf, Jonathan LaMarre, K P Crookston, M. Beatriz S. Lopes, Harold L. Moses, Steven L. Gonias, M. Anthony Hayes
Publikováno v:
Annals of the New York Academy of Sciences. 737:273-290
Publikováno v:
Journal of Biological Chemistry. 269:1533-1540
alpha 2-Macroglobulin (alpha 2M) binds numerous cytokines; however, since binding affinities have not been determined, it is difficult to compare various alpha 2M-cytokine interactions or predict whether alpha 2M-cytokine complexes will form in the p
Publikováno v:
Biochemical Journal. 293:443-450
alpha 2-Macroglobulin (alpha 2M) undergoes a major conformational change when reacting with proteinases or primary amines. This conformational change has been referred to as the ‘slow’ to ‘fast’ transformation based on the increase in alpha 2
Publikováno v:
British journal of haematology. 100(3)
We report a case where a phenotypic test (an activity assay for activated protein C resistance) correctly indicated that the patient had an abnormality, whereas the initial genetic test (a PCR-based DNA assay used to detect the mutation in the FV gen
Autor:
S L, Gonias, J, LaMarre, K P, Crookston, D J, Webb, B B, Wolf, M B, Lopes, H L, Moses, M A, Hayes
Publikováno v:
Annals of the New York Academy of Sciences. 737
Publikováno v:
The Journal of biological chemistry. 269(2)
alpha 2-Macroglobulin (alpha 2M) binds numerous cytokines; however, since binding affinities have not been determined, it is difficult to compare various alpha 2M-cytokine interactions or predict whether alpha 2M-cytokine complexes will form in the p