Zobrazeno 1 - 10
of 38
pro vyhledávání: '"K Naga Mohan"'
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0235547 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0228156.].
Externí odkaz:
https://doaj.org/article/38687f5d5bc04583bb18e40132c0a7d0
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0228156 (2020)
Mutations conferring susceptibility to complex disorders also occur in healthy individuals but at significantly lower frequencies than in patients, indicating that these mutations are not completely penetrant. Therefore, it is important to estimate t
Externí odkaz:
https://doaj.org/article/1acd558ce51c40c6a4d3480b26e70f13
Autor:
Leonardo D'Aiuto, Marco Marzulli, K Naga Mohan, Ewa Borowczyk, Federica Saporiti, Andrew Vandemark, J Richard Chaillet
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9831 (2010)
Deletion analysis of mouse DNMT1, the primary maintenance methyltransferase in mammals, showed that most of the N-terminal regulatory domain (amino acid residues 412-1112) is required for its enzymatic activity. Although analysis of deletion mutants
Externí odkaz:
https://doaj.org/article/b880c0e449d04591b6ef2ad16edb8250
Publikováno v:
Stem Cell Research, Vol 71, Iss , Pp 103141- (2023)
DNMT1 overexpression is reported in disorders like schizophrenia, bipolar, epilepsy and multiple cancer types. Here, we used non-homologous recombination to generate R1Dnmt1WT-1, a mouse embryonic stem cell (ESC) line carrying a Dnmt1 cDNA transgene
Externí odkaz:
https://doaj.org/article/f493620c83d447b4999baf2e91c097d4
Autor:
K. Naga Mohan
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Epigenetic mechanisms underlie differentiation of pluripotent stem cells into different lineages that contain identical genomes but express different sets of cell type-specific genes. Because of high discordance rates in monozygotic twins, epigenetic
Externí odkaz:
https://doaj.org/article/ba4e1e890ac24ee98715ff6c40e0c1d3
Autor:
Sumana Choudhury, K. Naga Mohan
Publikováno v:
Stem Cell Research, Vol 56, Iss, Pp 102561-(2021)
DNMT1 Y495C is the most common mutation associated with hereditary sensory and autonomic neuropathy type 1E, and dementia. Here we employed non-homologous recombination and generated a mouse embryonic stem cell line carrying a transgene expressing DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::590c2f71f1b7bb08bb9c1c8103309029
http://www.sciencedirect.com/science/article/pii/S1873506121004086
http://www.sciencedirect.com/science/article/pii/S1873506121004086
Autor:
Poornima Kkani, G Prasad Rao, Vidhya Chitta Voina, C Ramasubramanian, Kavitha Gowdhaman, Sonal Saxena, K. Naga Mohan, Pranay Amruth Maroju, S. Ganesh Kumar, Trinath Jamma, Kiranmai Chennoju, Sumana Choudhury, Poonam Naik, Kumar Pranav Narayan
Publikováno v:
Genetics Research, Vol 2021 (2021)
A recent study showed the association of minor alleles of rs2228611 (T allele) and rs2114724 (T allele) of DNMT1 with schizophrenia (SZ) and suggested their effects on splicing of the transcripts. We performed a replication study using 310 controls a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1a6053a6aff9658b08662627963272
https://doaj.org/article/28798b94df534441895eee949185e1f1
https://doaj.org/article/28798b94df534441895eee949185e1f1
Autor:
Sonal, Saxena, Pranay Amruth, Maroju, Sumana, Choudhury, Vidhya Chitta, Voina, Poonam, Naik, Kavitha, Gowdhaman, Poornima, Kkani, Kiranmai, Chennoju, S, Ganesh Kumar, C, Ramasubramanian, G, Prasad Rao, Trinath, Jamma, Kumar Pranav, Narayan, K Naga, Mohan
Publikováno v:
Genetics Research
A recent study showed the association of minor alleles of rs2228611 (T allele) and rs2114724 (T allele) of DNMT1 with schizophrenia (SZ) and suggested their effects on splicing of the transcripts. We performed a replication study using 310 controls a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4d2f5a1f8af675f332304538df8d98f
https://pubmed.ncbi.nlm.nih.gov/33854407
https://pubmed.ncbi.nlm.nih.gov/33854407
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 6, p e0235547 (2020)
PLoS ONE, Vol 15, Iss 6, p e0235547 (2020)
Mutations conferring susceptibility to complex disorders also occur in healthy individuals but at significantly lower frequencies than in patients, indicating that these mutations are not completely penetrant. Therefore, it is important to estimate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489dafb6bc49a19dbdccc2f79e63bf30
https://pubmed.ncbi.nlm.nih.gov/31995602
https://pubmed.ncbi.nlm.nih.gov/31995602
Publikováno v:
Gene. 757
Overexpression of DNA Methyltransferase I (DNMT1) is considered as one of the etiological factors for schizophrenia (SZ). However, information on genes subjected to dysregulation because of DNMT1 overexpression is limited. To test whether a larger gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660d95ef6dafe67b3b78429ed7f9f907
https://pubmed.ncbi.nlm.nih.gov/32640307
https://pubmed.ncbi.nlm.nih.gov/32640307