Zobrazeno 1 - 10
of 38
pro vyhledávání: '"K Naga, Mohan"'
Publikováno v:
Stem Cell Research, Vol 71, Iss , Pp 103141- (2023)
DNMT1 overexpression is reported in disorders like schizophrenia, bipolar, epilepsy and multiple cancer types. Here, we used non-homologous recombination to generate R1Dnmt1WT-1, a mouse embryonic stem cell (ESC) line carrying a Dnmt1 cDNA transgene
Externí odkaz:
https://doaj.org/article/f493620c83d447b4999baf2e91c097d4
Autor:
Sumana Choudhury, K. Naga Mohan
Publikováno v:
Stem Cell Research, Vol 56, Iss , Pp 102561- (2021)
DNMT1 Y495C is the most common mutation associated with hereditary sensory and autonomic neuropathy type 1E, and dementia. Here we employed non-homologous recombination and generated a mouse embryonic stem cell line carrying a transgene expressing DN
Externí odkaz:
https://doaj.org/article/205a3af9726848a68fbb5c2b69de0fec
Autor:
Sonal Saxena, Pranay Amruth Maroju, Sumana Choudhury, Vidhya Chitta Voina, Poonam Naik, Kavitha Gowdhaman, Poornima Kkani, Kiranmai Chennoju, S. Ganesh Kumar, C. Ramasubramanian, G. Prasad Rao, Trinath Jamma, Kumar Pranav Narayan, K. Naga Mohan
Publikováno v:
Genetics Research, Vol 2021 (2021)
A recent study showed the association of minor alleles of rs2228611 (T allele) and rs2114724 (T allele) of DNMT1 with schizophrenia (SZ) and suggested their effects on splicing of the transcripts. We performed a replication study using 310 controls a
Externí odkaz:
https://doaj.org/article/28798b94df534441895eee949185e1f1
Publikováno v:
Data in Brief, Vol 32, Iss , Pp 106242- (2020)
Defects in epigenetic mechanisms are well-recognized in multiple neurodevelopmental disorders including Schizophrenia (SZ). In addition to aberrant epigenetic marks, dysregulated epigenetic machinery was also identified among the contributory factors
Externí odkaz:
https://doaj.org/article/7603f1be052846f4a78e6060cc55c5f7
Publikováno v:
MethodsX, Vol 7, Iss , Pp 101073- (2020)
Investigation on the effects of disease-associated mutations on neurodevelopment is an essential approach to understand the molecular basis of neurological disorders and can be achieved by generating suitable animal models. However, some of the mutat
Externí odkaz:
https://doaj.org/article/ef6b32d957d34b529b9f7f653a674d10
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0235547 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0228156.].
Externí odkaz:
https://doaj.org/article/38687f5d5bc04583bb18e40132c0a7d0
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0228156 (2020)
Mutations conferring susceptibility to complex disorders also occur in healthy individuals but at significantly lower frequencies than in patients, indicating that these mutations are not completely penetrant. Therefore, it is important to estimate t
Externí odkaz:
https://doaj.org/article/1acd558ce51c40c6a4d3480b26e70f13
Autor:
K. Naga Mohan
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Epigenetic mechanisms underlie differentiation of pluripotent stem cells into different lineages that contain identical genomes but express different sets of cell type-specific genes. Because of high discordance rates in monozygotic twins, epigenetic
Externí odkaz:
https://doaj.org/article/ba4e1e890ac24ee98715ff6c40e0c1d3
Autor:
Poornima Kkani, G Prasad Rao, Vidhya Chitta Voina, C Ramasubramanian, Kavitha Gowdhaman, Sonal Saxena, K. Naga Mohan, Pranay Amruth Maroju, S. Ganesh Kumar, Trinath Jamma, Kiranmai Chennoju, Sumana Choudhury, Poonam Naik, Kumar Pranav Narayan
Publikováno v:
Genetics Research, Vol 2021 (2021)
A recent study showed the association of minor alleles of rs2228611 (T allele) and rs2114724 (T allele) of DNMT1 with schizophrenia (SZ) and suggested their effects on splicing of the transcripts. We performed a replication study using 310 controls a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1a6053a6aff9658b08662627963272
https://doaj.org/article/28798b94df534441895eee949185e1f1
https://doaj.org/article/28798b94df534441895eee949185e1f1
Autor:
Sonal, Saxena, Pranay Amruth, Maroju, Sumana, Choudhury, Vidhya Chitta, Voina, Poonam, Naik, Kavitha, Gowdhaman, Poornima, Kkani, Kiranmai, Chennoju, S, Ganesh Kumar, C, Ramasubramanian, G, Prasad Rao, Trinath, Jamma, Kumar Pranav, Narayan, K Naga, Mohan
Publikováno v:
Genetics Research
A recent study showed the association of minor alleles of rs2228611 (T allele) and rs2114724 (T allele) of DNMT1 with schizophrenia (SZ) and suggested their effects on splicing of the transcripts. We performed a replication study using 310 controls a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4d2f5a1f8af675f332304538df8d98f
https://pubmed.ncbi.nlm.nih.gov/33854407
https://pubmed.ncbi.nlm.nih.gov/33854407