Zobrazeno 1 - 10
of 28
pro vyhledávání: '"K N, Kashkin"'
Autor:
K. N. Kashkin
Publikováno v:
Russian Journal of Bioorganic Chemistry. 48:1230-1239
Abstract— Previously we demonstrated the tumor-specific activity of several human native and chimeric promoters. Here we have analyzed the DNA sequences of experimentally tested tumor-specific promoters for the presence of recognition matrices of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ed06d7d587940e8b9c334bfcbcedc1c
https://doi.org/10.1134/s1068162022060127
https://doi.org/10.1134/s1068162022060127
Autor:
K. N. Kashkin
This study supplements earlier received experimental data using modern databases. Previously tumor-specific activity of several human native and chimeric promoters was demonstrated. Here we compared tumor-specific promoters with promoters of housekee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b933de3620acc08b96dd79ff66dfe81e
https://doi.org/10.1101/2021.11.11.468214
https://doi.org/10.1101/2021.11.11.468214
Publikováno v:
BioTechniques. 63:107-116
Gene therapy is a fast-developing field of molecular medicine. New, effective, and cancer-specific promoters are in high demand by researchers seeking to treat cancer through expression of therapeutic genes. Here, we created a combinatorial library o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac679f1f006eb7d5879f34a0905486f6
https://doi.org/10.2144/000114586
https://doi.org/10.2144/000114586
Autor:
E. P. Kopantzev, K. N. Kashkin, Igor P. Chernov, E. A. Stukacheva, L. G. Kondratyeva, D. A. Dydich, E. D. Sverdlov
Publikováno v:
Molecular Genetics, Microbiology and Virology. 32:137-140
We have cloned the promoter of the human PCNA gene that codes for a proliferating cell-nuclear antigen. Two promoter DNA fragments were cloned of 1416 and 389 bp in length. Expression of luc and PDX1 genes under the control of the PCNA promoter was d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f5fff054dc53cb3e89f8c6fd997c843
https://doi.org/10.3103/s089141681703003x
https://doi.org/10.3103/s089141681703003x
Autor:
K. N. Kashkin, Eugene D. Sverdlov
Publikováno v:
Russian Journal of Bioorganic Chemistry. 42:473-478
The minireview is dedicated to recently described enhancer RNAs (eRNAs), which are products of enhancer transcription. Features and putative functions of eRNAs are considered. The potential of eRNAs as therapeutic targets is discussed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5a39864ffd459a432db6bf102c99213
https://doi.org/10.1134/s1068162016050083
https://doi.org/10.1134/s1068162016050083
Autor:
K. N. Kashkin, E. D. Sverdlov
Publikováno v:
Molecular Biology. 49:810-817
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3bce249b3ef6225760440dc1a312a98
https://doi.org/10.1134/s0026893315060114
https://doi.org/10.1134/s0026893315060114
Autor:
Eugene D. Sverdlov, K. N. Kashkin
Publikováno v:
Молекулярная биология. 49:905-914
This review is devoted to the mechanisms of transcriptional pause and poised state of RNA polymerase II. Features of poised promoters and chromatin are considered in brief. Role of regulated transcriptional pause as discrete and important stage in re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::513f1408f9fe74ca2ed62341bf128826
https://doi.org/10.7868/s0026898415060117
https://doi.org/10.7868/s0026898415060117
Autor:
Eugene D. Sverdlov, Galina S. Monastyrskaya, Natalya Uspenskaya, E. P. Kopantzev, E. A. Stukacheva, Igor P. Chernov, K. N. Kashkin
Publikováno v:
Journal of Cellular Biochemistry. 116:299-309
Violation of proliferation control is a common feature of cancer cells. We put forward the hypothesis that promoters of genes involved in the control of cell proliferation should possess intrinsic cancer specific activity. We cloned promoter regions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::897ec2e049234a28fe713c1f0aa335bc
https://doi.org/10.1002/jcb.24968
https://doi.org/10.1002/jcb.24968
Autor:
Ivan S. Yevshin, Yu. V. Kondrakhin, Ruslan N. Sharipov, A. V. Komelkov, Ulyana A. Boyarskikh, Fedor A. Kolpakov, Maksim L. Filipenko, E. M. Tchevkina, M. A. Sukoyan, K. N. Kashkin, E. A. Musatkina
Publikováno v:
Molecular Biology. 45:600-607
The goal of the present study was to define gene expression signatures that predict a chemosensitivity of nonsmall cell lung cancer (NSCLC) to cisplatin and paclitaxel. To generate a set of candidate genes likely to be predictive, current knowledge o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d337a3c56ba8694c0366d13a5d05315b
https://doi.org/10.1134/s0026893311030034
https://doi.org/10.1134/s0026893311030034
Autor:
I. B. Zborovskaya, Alexander G. Tonevitsky, K. N. Kashkin, Ya. A. Kainov, I. A. Favorskaya, Eugene D. Sverdlov, M. V. Zinovyeva, D. A. Sakharov, E. A. Musatkina, Tatyana V. Vinogradova, E. A. Tonevitsky, A. V. Komelkov, Vasily N. Aushev, E. P. Kopantsev
Publikováno v:
Doklady Biochemistry and Biophysics. 438:147-150
ISSN 16076729, Doklady Biochemistry and Biophysics, 2011, Vol. 438, pp. 147–150. © Pleiades Publishing, Ltd., 2011.Original Russian Text © K.N. Kashkin, E.A. Musatkina, A.V. Komelkov, E.A. Tonevitsky, D.A. Sakharov, T.V. Vinogradova, E.P. Kopants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16a77974be2f3368d28db1367f7799a
https://doi.org/10.1134/s1607672911030112
https://doi.org/10.1134/s1607672911030112