Zobrazeno 1 - 10
of 65
pro vyhledávání: '"K Momomura"'
Autor:
Yoshihiko Takahashi, Yoshio Yazaki, Takashi Kadowaki, Yasushi Kaburagi, Yasuo Akanuma, Kojiro Ueki, K Momomura, Kazuyuki Tobe, Toshimasa Yamauchi, Hiroyuki Tamemoto, Ritsuko Honda-Yamamoto
Publikováno v:
Endocrine Journal. 43:S33-S41
Insulin and insulin-like growth factor-1 (IGF-1) are two structurally related hormones which produce similar biological activities such as metabolic and growth promoting actions. Their receptors, insulin and IGF-1 receptors, also share similarities i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7402323563b3794cde154f69dc41b4a
https://doi.org/10.1507/endocrj.43.suppl_s33
https://doi.org/10.1507/endocrj.43.suppl_s33
Autor:
Takashi Kadowaki, Yasuo Akanuma, K Momomura, Kazuyuki Tobe, Yoshio Yazaki, Hiroshi Sakura, Ritsuko Yamamoto-Honda, Yasushi Kaburagi, Yoshikazu Tamori
Publikováno v:
Journal of Biological Chemistry. 268:16610-16622
We have studied the functions of the juxtamembrane domain (941-989) of the human insulin receptor by site-directed mutagenesis. Tyrosine phosphorylation of pp185 was impaired in Chinese hamster ovary cells expressing the receptors with the alteration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be86d45aa235c42f9e6a17379190186
https://doi.org/10.1016/s0021-9258(19)85463-7
https://doi.org/10.1016/s0021-9258(19)85463-7
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 263:E94-E101
Effects of fish oil feeding on glucose transport systems and cell size in rat adipocytes were examined and compared with those of safflower oil or carbohydrate feeding under isoenergy intake conditions. Glucose transport activity was assessed by meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8e79c65440ada5ee7dcde6cde774c9
https://doi.org/10.1152/ajpendo.1992.263.1.e94
https://doi.org/10.1152/ajpendo.1992.263.1.e94
Autor:
Toyohiro Tsukada, Masako Shimada, Nobuhiro Yamada, N Morisaki, T Gotoda, Kazuo Motoyoshi, K Momomura, H Shimano, Toshimori Inaba, Takashi Kadowaki
Publikováno v:
Journal of Biological Chemistry. 267:5693-5699
Vascular smooth muscle cells in atherosclerotic lesions are phenotypically different from those in the normal arterial wall, and no expression of macrophage colony stimulating factor (M-CSF) receptor encoded by the proto-oncogene c-fms has been demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf9b3a23d0f3017080300ae36496146
https://doi.org/10.1016/s0021-9258(18)42822-0
https://doi.org/10.1016/s0021-9258(18)42822-0
Autor:
Yasuo Akanuma, M Odawara, F Takaku, Masato Kasuga, Kazuyuki Tobe, Ritsuko Yamamoto-Honda, O Koshio, Yoshikazu Shibasaki, K Momomura, Takashi Kadowaki
Publikováno v:
Journal of Biological Chemistry. 265:14777-14783
Chinese hamster ovary (CHO) cell transfectants that expressed human insulin receptors whose glycine 996 was substituted by valine were studied. Receptor processing and insulin binding were unaffected by this mutation; however, this mutant insulin rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f46eb19298e7022d9c10ab708e7037
https://doi.org/10.1016/s0021-9258(18)77180-9
https://doi.org/10.1016/s0021-9258(18)77180-9
Autor:
K Momomura, Yuko Tashiro-Hashimoto, Masato Kasuga, Teruo Shiba, Takashi Kadowaki, Tetsuro Izumi, Kazuyuki Tobe
Publikováno v:
Diabetes Care. 13:317-326
Several studies suggest that the tyrosine-specific protein kinase activity of the β-subunit of the insulin receptor is necessary to mediate the biological effects of insulin. This conclusion leads to the hypothesis that the effect of insulin is medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff189dd7df09190789405f73a40921de
https://doi.org/10.2337/diacare.13.3.317
https://doi.org/10.2337/diacare.13.3.317
Autor:
Daisuke Kohda, Hiroshi Kataoka, K. Tamori, Fuyuhiko Inagaki, K Momomura, Hideki Hatanaka, Akira Isogai, Hironori Ishizaki, A Suzuki, Takashi Kadowaki, Koji Nagata, H. Nagasawa, Minoru Tanaka
Publikováno v:
Peptide Science — Present and Future ISBN: 0792352718
K. NAGATA1,2 , H. HATANAKA1 , D. KOHDA1 , H. ISHIZAKI3 , K. MOMOMURA4 , K. TAMORI4 , T. KADOWAKI4 , M. TANAKA2 , H. KATAOKA2 , H. NAGASAWA2 , A. ISOGAI2 , A. SUZUKI2 and F. INAGAKI1 1 Department of Molecular Physiology, The Tokyo Metropolitan Institu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::067c53e7aed2d85c129da901e7dc5514
https://doi.org/10.1007/0-306-46864-6_81
https://doi.org/10.1007/0-306-46864-6_81
Autor:
Takashi Kadowaki, Angus C. Maccuish, Yoshio Yazaki, Yoshihiko Takahashi, John D. Quin, Akifumi Ando, Yasuo Akanuma, Simeon I. Taylor, Naoya Koda, K Momomura, Hiroko Kadowaki, Yasushi Kaburagi, Yoshimitsu Fukushima
Publikováno v:
Biochemical and biophysical research communications. 237(3)
We identified four novel mutant alleles of the insulin receptor gene in three patients with genetic syndromes associated with insulin resistance. Two mutant alleles of the insulin receptor gene were identified in a patient with the Rabson-Mendenhall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38d7e02994e5638f3386238cd039d52
https://pubmed.ncbi.nlm.nih.gov/9299395
https://pubmed.ncbi.nlm.nih.gov/9299395
Autor:
Yoshihiko Takahashi, Yuji Taketani, Hiroko Kadowaki, Takashi Kadowaki, Yasuo Akanuma, T. Okai, Tihamer Orban, Yoshio Yazaki, Yasushi Fukushima, K Momomura
Publikováno v:
Diabetologia. 40(4)
We report a homozygous missense mutation at position 1092 (substitution of glutamine for arginine) in the tyrosine kinase domain of the insulin receptor in a patient with leprechaunism associated with severe insulin resistance and intrauterine growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be55822c479c06e19653d48f8f052a05
https://pubmed.ncbi.nlm.nih.gov/9112018
https://pubmed.ncbi.nlm.nih.gov/9112018
Autor:
Masato Kasuga, Yasuhiko Iwamoto, K Momomura, Masato Odawara, Yoshihiko Takahashi, C Matsumoto, Takuya Awata, Takashi Kadowaki
Publikováno v:
The Journal of clinical endocrinology and metabolism. 79(6)
We studied a woman with acanthosis nigricans and insulin resistance. The patient's Epstein-Barr virus-transformed lymphocytes revealed slightly decreased insulin binding and markedly decreased insulin-stimulated autophosphorylation of the insulin rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8e9887d2e969bd5c7c3a151318f631
https://pubmed.ncbi.nlm.nih.gov/7989492
https://pubmed.ncbi.nlm.nih.gov/7989492