Zobrazeno 1 - 10
of 46
pro vyhledávání: '"K M Zsebo"'
Publikováno v:
Blood. 82:445-455
We have examined the effects of administration of stem cell-factor (SCF) on the number and distribution of pluripotent hematopoietic stem cells (PHSC) in normal mice. Using the competitive repopulation assay we found that in vivo administration of SC
Publikováno v:
Blood. 82:436-444
Stem cell factor (SCF) acts in synergy with other growth factors such as erythropoietin (Epo), granulocyte-macrophage colony-stimulating factor (GM-CSF), or interleukin-3 (IL-3), to stimulate the growth of primitive hematopoietic cells. Because of th
Publikováno v:
The Journal of Immunology. 150:556-562
We examined whether three cytokines that promote mouse mast cell development, the c-kit ligand stem cell factor (SCF), IL-3, or IL-4, also can directly stimulate or modulate mouse peritoneal mast cell (PMC) mediator release. Challenge of purified PMC
Autor:
F G, Schuening, F R, Appelbaum, H J, Deeg, M, Sullivan-Pepe, T C, Graham, R, Hackman, K M, Zsebo, R, Storb
Publikováno v:
Blood. 81:20-26
The effects of recombinant canine stem cell factor (rcSCF) on hematopoiesis were studied in normal dogs and in dogs given otherwise lethal total body irradiation (TBI) without marrow transplant. Results were compared with previous and concurrent data
Autor:
A M, Irani, G, Nilsson, U, Miettinen, S S, Craig, L K, Ashman, T, Ishizaka, K M, Zsebo, L B, Schwartz
Publikováno v:
Blood. 80:3009-3021
We have previously shown the development in vitro of tryptase+ human mast cells from fetal liver cells cocultured with murine 3T3 fibroblasts. In this study, recombinant human stem cell factor (rhuSCF), the ligand for the c-kit proto-oncogene product
Autor:
R G, Andrews, W I, Bensinger, G H, Knitter, S H, Bartelmez, K, Longin, I D, Bernstein, F R, Appelbaum, K M, Zsebo
Publikováno v:
Blood. 80:2715-2720
Recombinant human stem cell factor (SCF), the ligand for c-kit, has been shown to stimulate increased numbers of hematopoietic progenitor cells of multiple types to circulate in the blood of baboons, but it was not known if the cells stimulated to ci
Publikováno v:
Blood. 80:1679-1684
Human kit ligand (KL), also known as stem cell factor (SCF), steel factor, or mast cell growth factor, is a recently identified hematopoietic growth factor whose receptor is the product of the c-kit proto-oncogene. Alternative splicing of the pre-mRN
Publikováno v:
Blood. 80:374-381
Human stem cell factor (SCF) acts in the presence of other growth factors to stimulate the growth of primitive hematopoietic progenitor cells. These effects are performed by activation of the SCF receptor, c- kit. Because of the potential use of SCF
Publikováno v:
Blood. 80:60-67
Stem cell factor (SCF) acts in concert with lineage-specific growth factors to stimulate the growth of hematopoietic colonies. To determine if neoplastic human hematopoietic cells would also respond to SCF, we cultured marrow mononuclear cells from 2
Autor:
M Takagi, T Nakahata, T Kubo, M Shiohara, K Koike, A Miyajima, K Arai, S Nishikawa, K M Zsebo, A Komiyama
Publikováno v:
The Journal of Immunology. 148:3446-3453
The proliferative capacity of mouse connective tissue-type mast cells (CTMC) was analyzed by using a newly discovered c-kit ligand, termed stem cell factor (SCF). More than 90% of CTMC in the peritoneal cavity responded to recombinant rat SCF (rrSCF)