Zobrazeno 1 - 8
of 8
pro vyhledávání: '"K M Felsenstein"'
Autor:
Jian Wang, Donna M. Barten, J Lubinski, R Krishna, J J Anderson, K M Felsenstein, S B Hansel, A Thakur, D W Boulton, K S Santone, Ming Yao, Ming Zheng, J M Pursley, Oliver P. Flint
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 39(7)
BMS-299897 is a gamma-secretase inhibitor that was effective in reducing amyloid beta-peptide (A beta) in transgenic mice and guinea pigs. Therefore, pharmacokinetic and drug metabolism studies were conducted in animals to support its clinical develo
Publikováno v:
Journal of neuroscience research. 38(1)
Phorbol esters (PDBu) stimulate α-secretase cleavage and secretion of the Alzheimer amyloid precursor protein (APP). To determine whether any cytoplasmic residues or sequence motifs mediate the PDBu effect on APP processing, this region of APP was a
Publikováno v:
The Journal of biological chemistry. 269(4)
The beta-amyloid precursor protein (beta-APP) is a membrane spanning glycoprotein. The small beta-protein domain within the precursor is presumed to be the source of amyloid found in plaques characteristic of Alzheimer's disease. The amino terminus o
Autor:
K M Felsenstein, Stephen P. Goff
Publikováno v:
Journal of virology. 66(11)
The gag-pol polyprotein of the murine and feline leukemia viruses is expressed by translational readthrough of a UAG terminator codon at the 3' end of the gag gene. To explore the cis-acting sequence requirements for the readthrough event in vivo, we
Autor:
S W Emmons, K M Felsenstein
Publikováno v:
Molecular and Cellular Biology. 8:875-883
Several members of a repetitive DNA family in the nematode Caenorhabditis elegans have been shown to express ARS and centromeric function in Saccharomyces cerevisiae. The repetitive family, denoted CeRep3, consists of dispersed repeated elements abou
Autor:
K M Felsenstein, Stephen P. Goff
Publikováno v:
Journal of Virology. 62:2179-2182
A mutant of Moloney murine leukemia virus was generated in which the UAG termination codon at the 3' end of the gag gene was changed to a CAG codon encoding glutamine. Cells carrying the mutant provirus constitutively express the gag-pol fusion prote
Autor:
K M, Felsenstein, S W, Emmons
Publikováno v:
Molecular and Cellular Biology. 8:875-883
Several members of a repetitive DNA family in the nematode Caenorhabditis elegans have been shown to express ARS and centromeric function in Saccharomyces cerevisiae. The repetitive family, denoted CeRep3, consists of dispersed repeated elements abou
Autor:
K M, Felsenstein
Publikováno v:
BioTechniques. 6(9)