Zobrazeno 1 - 10
of 26
pro vyhledávání: '"K M, Weidner"'
Publikováno v:
Clinical and Experimental Metastasis. 17:641-648
Interactions of tumor cells with the endothelium and tissue stroma are considered to be critical steps in metastasis formation and progression of cancer. To identify cellular receptors that mediate the binding of tumor cells to endothelium, a murine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22147e70944d10dee2e91c7177b09ab8
https://doi.org/10.1023/a:1006790912877
https://doi.org/10.1023/a:1006790912877
Publikováno v:
Journal of Biological Chemistry. 269:21936-21939
Scatter factor/hepatocyte growth factor (SF/HGF) has various biological effects upon different cells, i.e. induces increased motility and proliferation as well as invasiveness and morphogenesis. The signals given to epithelial cells by SF/HGF are all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3fa02ffc77e20ccec9fb5bf7a5d700a
https://doi.org/10.1016/s0021-9258(17)31736-2
https://doi.org/10.1016/s0021-9258(17)31736-2
Publikováno v:
The Journal of Cell Biology
Scatter factor/hepatocyte growth factor (SF/HGF) has potent motogenic, mitogenic, and morphogenetic activities on epithelial cells in vitro. The cell surface receptor for this factor was recently identified: it is the product of the c-met protooncoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dfe47b54289ac9119dc2ef4f10966f5
https://doi.org/10.1083/jcb.123.1.223
https://doi.org/10.1083/jcb.123.1.223
Publikováno v:
The Journal of Cell Biology
Depending on the target cells and culture conditions, scatter factor/hepatocyte growth factor (SF/HGF) mediates several distinct activities, i.e., cell motility, proliferation, invasiveness, tubular morphogenesis, angiogenesis, or cytotoxicity. A sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2712ea5d311d574a63965788038a8a
https://doi.org/10.1083/jcb.121.1.145
https://doi.org/10.1083/jcb.121.1.145
Publikováno v:
Journal of Biological Chemistry. 267:10281-10288
Anti-metatype antibodies have been described as antibodies which recognize ligand-induced conformational changes in the antibody variable region. Additionally, anti-metatype antibodies, produced by multiple immunizations with liganded high affinity m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c51628499f6d15801c8c98f7a82394ae
https://doi.org/10.1016/s0021-9258(19)50015-1
https://doi.org/10.1016/s0021-9258(19)50015-1
Autor:
K M Weidner, Edward W. Voss
Publikováno v:
Molecular Immunology. 29:303-312
Immunizations of high affinity anti-fluorescein monoclonal antibody 4-4-20 affinity labeled with fluorescein 5-isothiocyanate into a rabbit elicited antibodies specific for the liganded conformation of 4-4-20 (termed "anti-metatype" antibodies). Reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76e1b828090bf2a8e984f409b59f0da
https://doi.org/10.1016/0161-5890(92)90016-q
https://doi.org/10.1016/0161-5890(92)90016-q
Autor:
K M Weidner, Edward W. Voss
Publikováno v:
Journal of Biological Chemistry. 266:2513-2519
High affinity murine anti-fluorescein monoclonal antibody (Mab) 4-4-20 (K alpha = 1.3 x 10(10) M-1; IgG2a; kappa), affinity labeled with fluorescein isothiocyanate (I), served as the immunogen to elicit a xenogenic (rabbit) polyclonal "anti-metatype"
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f9ebb78179cca62b655a087a9cd86fc
https://doi.org/10.1016/s0021-9258(18)52274-2
https://doi.org/10.1016/s0021-9258(18)52274-2
Autor:
M W Pantoliano, L K Denzin, Edward W. Voss, K D Hardman, K M Weidner, L S Johnson, E D Asel, William D. Bedzyk
Publikováno v:
Journal of Biological Chemistry. 265:18615-18620
Single-chain antibody of the (NH2) VL-linker-VH (COOH) design, was constructed based on prototype high affinity anti-fluorescein monoclonal antibody (mAb) 4-4-20. Purified single-chain antibody (SCA) 4-4-20/212 was studied relative to Ig mAb 4-4-20 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3906b846984338c3dc628a86156e7eaf
https://doi.org/10.1016/s0021-9258(17)44796-x
https://doi.org/10.1016/s0021-9258(17)44796-x
Publikováno v:
Clinicalexperimental metastasis. 17(8)
Interactions of tumor cells with the endothelium and tissue stroma are considered to be critical steps in metastasis formation and progression of cancer. To identify cellular receptors that mediate the binding of tumor cells to endothelium, a murine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47d0b947e5eb2f11a406fc0bcaca821a
https://pubmed.ncbi.nlm.nih.gov/10919708
https://pubmed.ncbi.nlm.nih.gov/10919708
The Met tyrosine kinase receptor is a widely expressed molecule which mediates pleiotropic cellular responses following activation by its ligand, hepatocyte growth factor/scatter factor (HGF/SF). In this communication we demonstrate that significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2cd657b7ee06627aac258afc02f98d
https://europepmc.org/articles/PMC231806/
https://europepmc.org/articles/PMC231806/
