Výsledky vyhledávání - "K M, Vignali"

Profound enhancement of T cell activation mediated by the interaction between the TCR and the D3 domain of CD4

Autor: D A, Vignali, K M, Vignali

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 162(3)

CD4 plays an important role in the activation and development of CD4+ T cells. This is mediated via its bivalent interaction with MHC class II molecules and the TCR:CD3 complex through p56lck. Recent studies have implicated a third site of interactio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b48560dadd60a0391a338cefabc26957
https://pubmed.ncbi.nlm.nih.gov/9973399

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Immunoregulation of Th cells by naturally processed peptide antagonists

Autor: R T, Carson, D D, Desai, K M, Vignali, D A, Vignali

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 162(1)

Th cells recognize protein Ags as short peptides bound to MHC class II molecules. Altered peptide ligands can antagonize (inhibit) T cell responses to stimulatory peptides. Peptides generated by APC may contain peptide flanking residues (PFR), which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9accb9247f9d0412c7a7661c2462ab7e
https://pubmed.ncbi.nlm.nih.gov/9886362

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