Zobrazeno 1 - 3
of 3
pro vyhledávání: '"K M, Trotman"'
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 24:213-223
Multiple doses of arteether (ARTE) at 25 mg/kg cause CNS and anorectic toxicities in rats. The same dose of ARTE was used to study the toxicokinetics (TK) after multiple injections and the pharmacokinetics (PK) following single administration. Animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f842570b5a9bf0ed9bfe580f907f1dd
https://doi.org/10.1007/bf03190023
https://doi.org/10.1007/bf03190023
Publikováno v:
Transactions of the Royal Society of Tropical Medicine and Hygiene. 92:332-340
The pharmacokinetics, metabolism, protein binding, red blood cell (RBC) binding, stability in vitro, and acute and anorectic toxicity of artelinic acid (ARTL) were investigated in various animal species and human blood samples. Absorption and distrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45296c05774ce7d3d3294a9447ec33d5
https://doi.org/10.1016/s0035-9203(98)91033-1
https://doi.org/10.1016/s0035-9203(98)91033-1
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 26(4)
beta-Arteether (AE) is an endoperoxide sesquiterpene lactone derivative currently being developed for the treatment of severe, complicated malaria caused by multidrug-resistant Plasmodium falciparum. Studies were undertaken to determine which form(s)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25a9dfd3afc4fad9c194465af26b31f4
https://pubmed.ncbi.nlm.nih.gov/9531517
https://pubmed.ncbi.nlm.nih.gov/9531517