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Efficacy of Acylfulvene Illudin analogues against a metastatic lung carcinoma MV522 xenograft nonresponsive to traditional anticancer agents: retention of activity against various mdr phenotypes and unusual cytotoxicity against ERCC2 and ERCC3 DNA helicase-deficient cells

Autor: M J, Kelner, T C, McMorris, L, Estes, R J, Starr, M, Rutherford, M, Montoya, K M, Samson, R, Taetle

Publikováno v: Cancer research. 55(21)

Four second-generation Illudin analogues were synthesized and tested for antitumor activity using a metastatic lung carcinoma xenograft model resistant to conventional antitumor agents. One analogue, the parent illudofulvene-derivative called Acylful

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8e69fe4785b36395e586cee0cfc0ce36
https://pubmed.ncbi.nlm.nih.gov/7585533

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