Zobrazeno 1 - 10
of 18
pro vyhledávání: '"K M, Pisters"'
Autor:
S. Effendi, Lisa W. Le, J. Law, M. Chan, H. Albaba, K. M. Pisters, P. A. Bradbury, S. Gill, Natasha B. Leighl, J. Rothenstein, Tong Zhang, U. Zurawska, Dianne Zawisza, M. Trinkaus, S. Arif, Tracey L. Stockley, Donna M. Graham, Andrea S. Fung, M. Sawczak, Eric X. Chen
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 157
Introduction MEK inhibition is a potential therapeutic strategy in non-small cell lung cancer (NSCLC). This phase I study evaluates the MEK inhibitor binimetinib plus carboplatin and pemetrexed in stage IV non-squamous NSCLC patients (NCT02185690). M
Autor:
S. Effendie, M. Sawczak, U. Zurawska, Natasha B. Leighl, M. Trinkaus, K. M. Pisters, M. Chan, Jeffrey Rothenstein, Donna M. Graham, Dianne Zawisza, Eric Chen, S. Arif, P. A. Bradbury
Publikováno v:
Journal of Thoracic Oncology. 13:S481-S482
Publikováno v:
American Journal of Clinical Oncology. 18:303-306
This study determined the maximum tolerated dose (MTD) of ifosfamide that could be given with high-dose cisplatin to non-small cell lung cancer (NSCLC) patients previously treated with non-platin-containing chemotherapy and to assess the efficacy of
Autor:
S A, Laurie, D G, Pfister, M G, Kris, W P, Tong, G, Chronowski, K M, Pisters, R T, Heelan, F M, Sirotnak
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(3)
The antifolate edatrexate has shown moderate activity against cancers of the head and neck and non-small cell lung cancer, as has cisplatin. Edatrexate demonstrates synergy with cisplatin in transplanted tumor models. This Phase I study was designed
Publikováno v:
Chest surgery clinics of North America. 11(1)
This article reviews changes in the roles of surgeons, medical oncologists, and radiation oncologists that have occurred over the past 20 years. A gradual evolution will certainly continue over the next several decades in the multidisciplinary quest
Autor:
K M, Pisters, R J, Ginsberg, D J, Giroux, J B, Putnam, M G, Kris, D H, Johnson, J R, Roberts, J, Mault, J J, Crowley, P A, Bunn
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 119(3)
This phase II trial assessed the feasibility, as measured by response rate, toxicity, resectability rate, and surgical morbidity and mortality rates, of perioperative paclitaxel and carboplatin chemotherapy in patients with early-stage non-small cell
Autor:
K K, Ng, M G, Kris, R J, Ginsberg, R T, Heelan, K M, Pisters, V A, Miller, S C, Grant, M, Bains, V, Rusch, K E, Rosenzweig, N, Martini
Publikováno v:
Cancer. 86(7)
Cisplatin-based induction chemotherapy before surgery or irradiation has improved the survival of patients with Stage III nonsmall cell lung carcinoma (NSCLC). Encouraged by earlier results with preoperative MVP (cisplatin [120 mg/m(2) or 25 mg/m(2)/
Autor:
K M, Pisters, M G, Kris, P A, Bunn, D H, Johnson, J C, Ruckdeschel, J J, Crowley, R J, Ginsberg
Publikováno v:
Seminars in oncology. 24(4 Suppl 12)
In this feasibility study, a 3-hour infusion of 225 mg/m2 paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ) was combined with carboplatin dosed to an area under the concentration-time curve of 6 to treat patients with stage T2N0, T1-2N1
Publikováno v:
Seminars in oncology. 24(4 Suppl 12)
Chemotherapy has been rarely considered an important treatment modality for brain metastases. Based on the hypothesis that the lack of efficacy of chemotherapy, rather than the blood-brain barrier itself, may be the major hindrance to the successful
Autor:
K M, Pisters, L B, Tyson, W, Tong, M, Fleisher, V A, Miller, S C, Grant, D G, Pfister, J R, Rigas, C L, Densmore, G, Krol, R T, Heelan, F M, Sirotnak, J R, Bertino, M G, Kris
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 2(11)
Our objective was to determine the maximum tolerated dose and toxicity of i.v. edatrexate with p.o. leucovorin. Thirty-one adults with advanced solid tumors received edatrexate as a 2-h infusion, once a week for 3 weeks, recycled every 28 days. p.o.